STRINGSTRING
WWC1 WWC1 WWC3 WWC3 SYTL1 SYTL1 DOCK4 DOCK4 UNC13D UNC13D RPGRIP1L RPGRIP1L PLA2G4E PLA2G4E PIK3CD PIK3CD ITSN2 ITSN2 ITCH ITCH PKN3 PKN3 ASCC3 ASCC3 RASA2 RASA2 WWP1 WWP1 CPNE3 CPNE3 SYT14 SYT14 SYTL2 SYTL2 PLCD3 PLCD3 RIMS2 RIMS2 UNC13C UNC13C RASA3 RASA3 RASA1 RASA1 ESYT1 ESYT1 PRKCA PRKCA PLCD4 PLCD4 LOC106024982 LOC106024982 DOCK1 DOCK1 RPH3A RPH3A UNC13A UNC13A PRKCE PRKCE BCR BCR LOC100734527 LOC100734527 PLCG1 PLCG1 PKN1 PKN1 SYT3 SYT3 H0W0D7_CAVPO H0W0D7_CAVPO SYT12 SYT12 Aida Aida H0VB67_CAVPO H0VB67_CAVPO SYT13 SYT13 ESYT3 ESYT3 PLCL2 PLCL2 DNAJC6 DNAJC6 CPNE9 CPNE9 CPNE8 CPNE8 HECW2 HECW2 SYT5 SYT5 PCLO PCLO ESYT2 ESYT2 PIK3C2A PIK3C2A FER1L6 FER1L6 SMURF1 SMURF1 HECW1 HECW1 OTOF OTOF RAB11FIP2 RAB11FIP2 SYT17 SYT17 TNS3 TNS3 BAIAP3 BAIAP3 Rasa4b Rasa4b SYT7 SYT7 PLCD1 PLCD1 CAPN6 CAPN6 NEDD4 NEDD4 ITSN1 ITSN1 PIK3CB PIK3CB DOCK9 DOCK9 SYDE2 SYDE2 RIMS3 RIMS3 SYT1 SYT1 PLCG2 PLCG2 WWC2 WWC2 SEC63 SEC63 Prkch Prkch RPGRIP1 RPGRIP1 C2CD5 C2CD5 C2CD2 C2CD2 SYNGAP1 SYNGAP1 RASAL3 RASAL3 SYT2 SYT2 PRKCB PRKCB CPNE6 CPNE6 CPNE4 CPNE4 SYTL4 SYTL4 CAPN5 CAPN5 SYTL3 SYTL3 SYT9 SYT9 PIK3C3 PIK3C3 PLCH1 PLCH1 SYT11 SYT11 MCTP1 MCTP1 CC2D1B CC2D1B FER1L5 FER1L5 MCTP2 MCTP2 DOCK10 DOCK10 DOCK11 DOCK11 PIK3C2B PIK3C2B DOCK3 DOCK3 Rab11fip1 Rab11fip1 PRF1 PRF1 LOC101788042 LOC101788042 DOCK2 DOCK2 DOCK8 DOCK8 PLCB2 PLCB2 PLCB4 PLCB4 C2CD4D C2CD4D RASAL2 RASAL2 TNS1 TNS1 CC2D1A CC2D1A DAB2IP DAB2IP WWP2 WWP2 PIK3CG PIK3CG PRKCQ PRKCQ Rims1 Rims1 SYT6 SYT6 DOCK7 DOCK7 PLCH2 PLCH2 PKN2 PKN2 ABR ABR PRKCD PRKCD INPP4B INPP4B SYTL5 SYTL5 INPP4A INPP4A GAK GAK SMURF2 SMURF2 SYT4 SYT4 MYOF MYOF PLCE1 PLCE1 NEDD4L NEDD4L PRKCG PRKCG ENSCPOP00000024042 ENSCPOP00000024042 PLCB1 PLCB1 PLA2G4A PLA2G4A UNC13B UNC13B TOLLIP TOLLIP SYT8 SYT8 DOCK5 DOCK5 PLCB3 PLCB3 CPNE7 CPNE7 C2CD4C C2CD4C RAB11FIP5 RAB11FIP5 CPNE5 CPNE5 CPNE1 CPNE1 DOCK6 DOCK6 CEP120 CEP120 CPNE2 CPNE2 TNS2 TNS2 DOC2B DOC2B PTEN PTEN DOC2A DOC2A RASAL1 RASAL1 LOC100721187 LOC100721187 PLA2G4D PLA2G4D PLA2G4F PLA2G4F C2CD2L C2CD2L PIK3CA PIK3CA PLCZ1 PLCZ1 SNRNP200 SNRNP200 SYT10 SYT10 CC2D2A CC2D2A UVRAG UVRAG DYSF DYSF RIMS4 RIMS4 C2CD3 C2CD3 TC2N TC2N PLCL1 PLCL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WWC1WW and C2 domain containing 1. (1107 aa)
WWC3WWC family member 3. (1090 aa)
SYTL1Synaptotagmin like 1. (558 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1970 aa)
UNC13DUnc-13 homolog D. (1100 aa)
RPGRIP1LRPGRIP1 like. (1260 aa)
PLA2G4EPhospholipase A2. (805 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
ITSN2Intersectin 2. (1684 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
PKN3Protein kinase N3. (881 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3. (2185 aa)
RASA2RAS p21 protein activator 2. (850 aa)
WWP1E3 ubiquitin-protein ligase. (912 aa)
CPNE3Copine 3. (523 aa)
SYT14Synaptotagmin 14. (587 aa)
SYTL2Synaptotagmin like 2. (923 aa)
PLCD3Phosphoinositide phospholipase C. (785 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1410 aa)
UNC13CUnc-13 homolog C. (2198 aa)
RASA3RAS p21 protein activator 3. (833 aa)
RASA1RAS p21 protein activator 1. (1024 aa)
ESYT1Extended synaptotagmin 1. (1092 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa)
PLCD4Phosphoinositide phospholipase C. (762 aa)
LOC106024982Phospholipase A2. (795 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1865 aa)
RPH3ARabphilin 3A. (667 aa)
UNC13AUnc-13 homolog A. (1650 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
BCRBCR activator of RhoGEF and GTPase. (1227 aa)
LOC100734527Double C2-like domain-containing protein. (399 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1235 aa)
PKN1Protein kinase N1. (946 aa)
SYT3Synaptotagmin 3. (587 aa)
H0W0D7_CAVPOAida_C2 domain-containing protein. (248 aa)
SYT12Synaptotagmin 12. (421 aa)
AidaUncharacterized protein. (306 aa)
H0VB67_CAVPOPhosphatidylinositol 3-kinase catalytic subunit type 3. (651 aa)
SYT13Synaptotagmin 13. (373 aa)
ESYT3Extended synaptotagmin 3. (884 aa)
PLCL2Phosphoinositide phospholipase C. (1009 aa)
DNAJC6DnaJ heat shock protein family (Hsp40) member C6. (901 aa)
CPNE9Copine family member 9. (553 aa)
CPNE8Copine 8. (516 aa)
HECW2HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2. (1566 aa)
SYT5Synaptotagmin 5. (386 aa)
PCLOPiccolo presynaptic cytomatrix protein. (3548 aa)
ESYT2Extended synaptotagmin 2. (763 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1404 aa)
FER1L6Fer-1 like family member 6. (1862 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1579 aa)
OTOFOtoferlin. (1980 aa)
RAB11FIP2RAB11 family interacting protein 2. (523 aa)
SYT17Synaptotagmin 17. (474 aa)
TNS3Tensin 3. (1562 aa)
BAIAP3BAI1 associated protein 3. (1152 aa)
Rasa4bUncharacterized protein. (802 aa)
SYT7Synaptotagmin 7. (556 aa)
PLCD1Phosphoinositide phospholipase C. (755 aa)
CAPN6Calpain 6; Belongs to the peptidase C2 family. (641 aa)
NEDD4E3 ubiquitin-protein ligase. (896 aa)
ITSN1Intersectin 1. (1657 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1018 aa)
DOCK9Dedicator of cytokinesis 9; Belongs to the DOCK family. (2052 aa)
SYDE2Synapse defective Rho GTPase homolog 2. (1196 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
SYT1Synaptotagmin 1. (422 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1270 aa)
WWC2WW and C2 domain containing 2. (1151 aa)
SEC63SEC63 homolog, protein translocation regulator. (742 aa)
PrkchUncharacterized protein. (543 aa)
RPGRIP1RPGR interacting protein 1. (1117 aa)
C2CD5C2 calcium dependent domain containing 5. (1035 aa)
C2CD2C2 calcium dependent domain containing 2. (690 aa)
SYNGAP1Synaptic Ras GTPase activating protein 1. (1284 aa)
RASAL3RAS protein activator like 3. (1024 aa)
SYT2Synaptotagmin 2. (421 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (643 aa)
CPNE6Copine 6. (557 aa)
CPNE4Copine 4. (557 aa)
SYTL4Synaptotagmin like 4. (671 aa)
CAPN5Calpain 5; Belongs to the peptidase C2 family. (618 aa)
SYTL3Synaptotagmin like 3. (608 aa)
SYT9Synaptotagmin 9. (487 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
PLCH1Phosphoinositide phospholipase C. (1665 aa)
SYT11Synaptotagmin 11. (431 aa)
MCTP1Multiple C2 and transmembrane domain containing 1. (763 aa)
CC2D1BCoiled-coil and C2 domain containing 1B. (850 aa)
FER1L5Fer-1 like family member 5. (2020 aa)
MCTP2Multiple C2 and transmembrane domain containing 2. (865 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2198 aa)
DOCK11Dedicator of cytokinesis 11; Belongs to the DOCK family. (2074 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1633 aa)
DOCK3Dedicator of cytokinesis 3; Belongs to the DOCK family. (2001 aa)
Rab11fip1Uncharacterized protein. (638 aa)
PRF1Perforin 1. (554 aa)
LOC101788042C2 domain-containing protein. (110 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1843 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2074 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
C2CD4DC2 calcium dependent domain containing 4D. (339 aa)
RASAL2RAS protein activator like 2. (1280 aa)
TNS1Tensin 1. (1593 aa)
CC2D1ACoiled-coil and C2 domain containing 1A. (947 aa)
DAB2IPDAB2 interacting protein. (1193 aa)
WWP2E3 ubiquitin-protein ligase. (870 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1092 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (705 aa)
Rims1C2 domain-containing protein. (219 aa)
SYT6Synaptotagmin 6. (512 aa)
DOCK7Dedicator of cytokinesis 7; Belongs to the DOCK family. (2006 aa)
PLCH2Phosphoinositide phospholipase C. (1461 aa)
PKN2Protein kinase N2. (982 aa)
ABRABR activator of RhoGEF and GTPase. (859 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
INPP4BInositol polyphosphate-4-phosphatase type II B. (939 aa)
SYTL5Synaptotagmin like 5. (715 aa)
INPP4AInositol polyphosphate-4-phosphatase type I A. (972 aa)
GAKCyclin G associated kinase. (1310 aa)
SMURF2E3 ubiquitin-protein ligase. (782 aa)
SYT4Synaptotagmin 4. (425 aa)
MYOFMyoferlin. (2033 aa)
PLCE1Phosphoinositide phospholipase C. (2282 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (992 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa)
ENSCPOP00000024042Uncharacterized protein. (143 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1217 aa)
PLA2G4APhospholipase A2. (749 aa)
UNC13BUnc-13 homolog B. (1959 aa)
TOLLIPToll interacting protein. (274 aa)
SYT8Synaptotagmin 8. (398 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1899 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1227 aa)
CPNE7Copine 7. (552 aa)
C2CD4CC2 calcium dependent domain containing 4C. (362 aa)
RAB11FIP5RAB11 family interacting protein 5. (636 aa)
CPNE5Copine 5. (593 aa)
CPNE1Copine 1. (537 aa)
DOCK6Dedicator of cytokinesis 6; Belongs to the DOCK family. (2063 aa)
CEP120Centrosomal protein 120. (952 aa)
CPNE2Copine 2. (548 aa)
TNS2Tensin 2. (1396 aa)
DOC2BDouble C2 domain beta. (340 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (355 aa)
DOC2ADouble C2-like domain-containing protein. (401 aa)
RASAL1RAS protein activator like 1. (801 aa)
LOC100721187Uncharacterized protein. (489 aa)
PLA2G4DPhospholipase A2. (790 aa)
PLA2G4FPhospholipase A2. (842 aa)
C2CD2LC2CD2 like. (701 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1044 aa)
PLCZ1Phosphoinositide phospholipase C. (601 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2136 aa)
SYT10Synaptotagmin 10. (521 aa)
CC2D2ACoiled-coil and C2 domain containing 2A. (1623 aa)
UVRAGUV radiation resistance associated. (698 aa)
DYSFDysferlin. (2103 aa)
RIMS4Regulating synaptic membrane exocytosis 4. (253 aa)
C2CD3C2 domain containing 3 centriole elongation regulator. (2326 aa)
TC2NTandem C2 domains, nuclear. (487 aa)
PLCL1Phosphoinositide phospholipase C. (1011 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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