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ACTN1 ACTN1 MYO1E MYO1E MYO19 MYO19 Myh4 Myh4 MYO10 MYO10 MYO18A MYO18A FLNA FLNA MYO9A MYO9A EVL EVL CNN3 CNN3 SYNE2 SYNE2 MYH10 MYH10 MYO16 MYO16 ACTN2 ACTN2 Myo5b Myo5b MYO1H MYO1H PFN3 PFN3 MYO9B MYO9B SPTB SPTB LOC101787807 LOC101787807 CAPZA3 CAPZA3 SHROOM1 SHROOM1 MYO7A MYO7A ARPC4 ARPC4 MACF1 MACF1 ARPC1B ARPC1B MYO1G MYO1G ACTR2 ACTR2 MYH8 MYH8 PLEC PLEC ENSCPOP00000023557 ENSCPOP00000023557 MYH1 MYH1 ACTN4 ACTN4 MYO5A MYO5A FLNB FLNB VASP VASP CNN1 CNN1 PFN4 PFN4 SPTBN4 SPTBN4 DMD DMD MYH11 MYH11 PLS3 PLS3 Cfl1 Cfl1 FSCN1 FSCN1 MYO1F MYO1F CAPZA2 CAPZA2 MYO5C MYO5C MYH7 MYH7 FSCN2 FSCN2 FSCN3 FSCN3 DSTN DSTN DST DST PHACTR3 PHACTR3 CLMN CLMN Myh2 Myh2 MYH7B MYH7B ARPC3 ARPC3 MYO15A MYO15A MYH15 MYH15 ACTN3 ACTN3 LCP1 LCP1 ARPC1A ARPC1A UTRN UTRN MYH9 MYH9 MYH14 MYH14 PHACTR1 PHACTR1 PLS1 PLS1 MYO3B MYO3B MYO1C MYO1C MYO1B MYO1B MYH6 MYH6 Tmsb4x Tmsb4x LOC106027361 LOC106027361 PHACTR4 PHACTR4 ENSCPOP00000032565 ENSCPOP00000032565 CAPZA1 CAPZA1 ENSCPOP00000032955 ENSCPOP00000032955 MYO1A MYO1A XIRP2 XIRP2 SPTBN2 SPTBN2 PHACTR2 PHACTR2 H0VPD8_CAVPO H0VPD8_CAVPO SHROOM3 SHROOM3 CAPZB CAPZB MYO6 MYO6 CNN2 CNN2 MYO18B MYO18B MYH3 MYH3 ARPC2 ARPC2 CFL2 CFL2 PFN1 PFN1 PFN2 PFN2 MYH13 MYH13 SPTBN1 SPTBN1 FLNC FLNC MYO1D MYO1D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACTN1Actinin alpha 1. (914 aa)
MYO1EMyosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1108 aa)
MYO19Myosin XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (957 aa)
Myh4Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1882 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2051 aa)
MYO18AMyosin XVIIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2083 aa)
FLNAFilamin A. (2645 aa)
MYO9AMyosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2603 aa)
EVLEnah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (420 aa)
CNN3Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (310 aa)
SYNE2Spectrin repeat containing nuclear envelope protein 2. (6922 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1974 aa)
MYO16Myosin XVI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1797 aa)
ACTN2Actinin alpha 2. (894 aa)
Myo5bUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1803 aa)
MYO1HMyosin IH; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1038 aa)
PFN3Profilin; Belongs to the profilin family. (137 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1930 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2358 aa)
LOC101787807Profilin; Belongs to the profilin family. (153 aa)
CAPZA3F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (263 aa)
SHROOM1Shroom family member 1. (678 aa)
MYO7AMyosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2203 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (176 aa)
MACF1Microtubule actin crosslinking factor 1. (7286 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
MYO1GMyosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1018 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
MYH8Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
PLECPlectin. (4689 aa)
ENSCPOP00000023557Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (657 aa)
MYH1Myosin heavy chain 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1884 aa)
ACTN4Actinin alpha 4. (911 aa)
MYO5AMyosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1877 aa)
FLNBFilamin B. (2602 aa)
VASPVasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (376 aa)
CNN1Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (256 aa)
PFN4Profilin; Belongs to the profilin family. (129 aa)
SPTBN4Spectrin beta chain; Belongs to the spectrin family. (2530 aa)
DMDDystrophin. (3613 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1982 aa)
PLS3Plastin 3. (637 aa)
Cfl1Cofilin 1; Belongs to the actin-binding proteins ADF family. (218 aa)
FSCN1Fascin. (493 aa)
MYO1FMyosin IF; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1098 aa)
CAPZA2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (279 aa)
MYO5CMyosin VC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1698 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1949 aa)
FSCN2Fascin. (492 aa)
FSCN3Fascin. (498 aa)
DSTNDestrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (164 aa)
DSTDystonin. (5380 aa)
PHACTR3Phosphatase and actin regulator. (506 aa)
CLMNCalmin. (974 aa)
Myh2Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1942 aa)
MYH7BMyosin heavy chain 7B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1941 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
MYO15AMyosin XVA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3221 aa)
MYH15Myosin heavy chain 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1926 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (889 aa)
LCP1Lymphocyte cytosolic protein 1. (627 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
UTRNUtrophin. (3432 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2034 aa)
PHACTR1Phosphatase and actin regulator. (649 aa)
PLS1Plastin 1. (630 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1306 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1078 aa)
MYO1BMyosin IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1136 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
Tmsb4xThymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa)
LOC106027361Uncharacterized protein. (1433 aa)
PHACTR4Phosphatase and actin regulator. (713 aa)
ENSCPOP00000032565Uncharacterized protein. (1114 aa)
CAPZA1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
ENSCPOP00000032955Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (43 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
XIRP2Xin actin binding repeat containing 2. (3296 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2386 aa)
PHACTR2Phosphatase and actin regulator. (635 aa)
H0VPD8_CAVPOUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (749 aa)
SHROOM3Shroom family member 3. (1837 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (301 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1294 aa)
CNN2Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (306 aa)
MYO18BMyosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2559 aa)
MYH3Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
PFN1Profilin; Belongs to the profilin family. (140 aa)
PFN2Profilin; Belongs to the profilin family. (140 aa)
MYH13Myosin heavy chain 13; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2364 aa)
FLNCFilamin C. (2726 aa)
MYO1DMyosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1006 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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