STRINGSTRING
LIMD1 LIMD1 PSMB1 PSMB1 PSMB6 PSMB6 CUL2 CUL2 PSMB9 PSMB9 CITED2 CITED2 EGLN2 EGLN2 PSMD13 PSMD13 PSMC4 PSMC4 HIF1A HIF1A EP300 EP300 Rps27a Rps27a PSMD6 PSMD6 PSMB7 PSMB7 PSMC6 PSMC6 PSMD11 PSMD11 HIF1AN HIF1AN PSMD8 PSMD8 PSMD7 PSMD7 PSMC5 PSMC5 PSME4 PSME4 PSMA8 PSMA8 EGLN3 EGLN3 PSMA5 PSMA5 PSMF1 PSMF1 PSMB5 PSMB5 PSMA7 PSMA7 EPAS1 EPAS1 Psmd10 Psmd10 PSMD3 PSMD3 PSMB4 PSMB4 PSMA1 PSMA1 HIF3A HIF3A PSMC2 PSMC2 H0VWS1_CAVPO H0VWS1_CAVPO EPO EPO Egln1 Egln1 AJUBA AJUBA Psmd9 Psmd9 PSMA4 PSMA4 Elob Elob Vhl Vhl PSMB3 PSMB3 PSMB11 PSMB11 PSMD5 PSMD5 H0WAD6_CAVPO H0WAD6_CAVPO PSMB10 PSMB10 H0WDT2_CAVPO H0WDT2_CAVPO UBE2D1 UBE2D1 PSMD1 PSMD1 PSMA3 PSMA3 ENSCPOP00000023065 ENSCPOP00000023065 PSME1 PSME1 ENSCPOP00000023919 ENSCPOP00000023919 PSMC3 PSMC3 PSMD2 PSMD2 RBX1 RBX1 UBE2D3 UBE2D3 PSMD14 PSMD14 PSMD4 PSMD4 WTIP WTIP PSMD12 PSMD12 PSMB2 PSMB2 PSMA6 PSMA6 UBB UBB ELOC ELOC PSMC1 PSMC1 ENSCPOP00000031632 ENSCPOP00000031632 PSME2 PSME2 Ubc Ubc Psma2 Psma2 UBE2D2 UBE2D2 PSME3 PSME3 ENSCPOP00000032781 ENSCPOP00000032781 PSMB8 PSMB8 HIGD1A HIGD1A UBA52 UBA52
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LIMD1LIM domains containing 1. (646 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMB6Proteasome subunit beta. (239 aa)
CUL2Cullin 2; Belongs to the cullin family. (745 aa)
PSMB9Proteasome subunit beta. (219 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (269 aa)
EGLN2Egl-9 family hypoxia inducible factor 2. (410 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (315 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (828 aa)
EP300E1A binding protein p300. (2425 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
HIF1ANHypoxia inducible factor 1 subunit alpha inhibitor. (334 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSME4Proteasome activator subunit 4. (1827 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
EGLN3Egl-9 family hypoxia inducible factor 3. (239 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMA7Proteasome endopeptidase complex. (248 aa)
EPAS1Endothelial PAS domain protein 1. (833 aa)
Psmd10ANK_REP_REGION domain-containing protein. (232 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (263 aa)
PSMA1Proteasome subunit alpha type. (270 aa)
HIF3AHypoxia inducible factor 3 subunit alpha. (667 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (458 aa)
H0VWS1_CAVPOANK_REP_REGION domain-containing protein. (213 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
Egln1Fe2OG dioxygenase domain-containing protein. (127 aa)
AJUBAAjuba LIM protein. (546 aa)
Psmd9PDZ domain-containing protein. (223 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
ElobUbiquitin-like domain-containing protein. (118 aa)
VhlUncharacterized protein. (182 aa)
PSMB3Proteasome subunit beta. (207 aa)
PSMB11Proteasome subunit beta. (297 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
PSMB10Proteasome subunit beta. (273 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (139 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
ENSCPOP00000023065ANK_REP_REGION domain-containing protein. (179 aa)
PSME1Proteasome activator subunit 1. (249 aa)
ENSCPOP00000023919Uncharacterized protein. (118 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
RBX1Ring-box 1. (108 aa)
UBE2D3Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (377 aa)
WTIPWT1 interacting protein. (268 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
ELOCElongin C; Belongs to the SKP1 family. (112 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
PSME2Proteasome activator subunit 2. (239 aa)
UbcUncharacterized protein. (159 aa)
Psma2Proteasome subunit alpha type. (234 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
PSME3Proteasome activator subunit 3. (254 aa)
ENSCPOP00000032781UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
PSMB8Proteasome subunit beta. (273 aa)
HIGD1AHIG1 hypoxia inducible domain family member 1A. (95 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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