STRINGSTRING
Mknk1 Mknk1 UBA52 UBA52 FNDC3A FNDC3A PPP2CB PPP2CB Rps27a Rps27a LOC100734047 LOC100734047 FNDC3B FNDC3B MAPK1 MAPK1 PTPN11 PTPN11 MKNK2 MKNK2 H0W160_CAVPO H0W160_CAVPO H0WAD6_CAVPO H0WAD6_CAVPO H0WDT2_CAVPO H0WDT2_CAVPO MAPK3 MAPK3 PPP2CA PPP2CA CBL CBL UBB UBB SPRY2 SPRY2 ENSCPOP00000031632 ENSCPOP00000031632 GRB2 GRB2 BRAF BRAF Ubc Ubc
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Mknk1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (421 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
FNDC3AFibronectin type III domain containing 3A. (1172 aa)
PPP2CBSerine/threonine-protein phosphatase. (308 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
LOC100734047Uncharacterized protein. (567 aa)
FNDC3BFibronectin type III domain containing 3B. (1101 aa)
MAPK1Mitogen-activated protein kinase. (325 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (588 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (465 aa)
H0W160_CAVPOUncharacterized protein. (589 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
CBLCbl proto-oncogene. (894 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
SPRY2Sprouty RTK signaling antagonist 2. (316 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (738 aa)
UbcUncharacterized protein. (159 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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