STRINGSTRING
Kcng2 Kcng2 KCNA2 KCNA2 KCNB1 KCNB1 KCNV2 KCNV2 GNG4 GNG4 KCNJ16 KCNJ16 ENSCPOP00000030509 ENSCPOP00000030509 ABCC9 ABCC9 Kcnj2 Kcnj2 GNGT2 GNGT2 KCND1 KCND1 ENSCPOP00000031524 ENSCPOP00000031524 KCNK2 KCNK2 KCNA7 KCNA7 Kcnj3 Kcnj3 GNG8 GNG8 KCNA4 KCNA4 KCNMA1 KCNMA1 KCNJ5 KCNJ5 Gng5 Gng5 KCNJ10 KCNJ10 KCNG4 KCNG4 GNG12 GNG12 KCNQ2 KCNQ2 GNB4 GNB4 GNG11 GNG11 GNG2 GNG2 KCNH8 KCNH8 Kcnk6 Kcnk6 KCNK16 KCNK16 GNG7 GNG7 KCNG1 KCNG1 KCNS1 KCNS1 KCNA6 KCNA6 KCNK13 KCNK13 GNG3 GNG3 KCNJ15 KCNJ15 KCNMB1 KCNMB1 GABBR1 GABBR1 HCN2 HCN2 KCNH7 KCNH7 HCN4 HCN4 KCNJ9 KCNJ9 H0WBW4_CAVPO H0WBW4_CAVPO KCNJ11 KCNJ11 KCNH4 KCNH4 GPR156 GPR156 KCNK4 KCNK4 KCNA5 KCNA5 HCN3 HCN3 KCNN1 KCNN1 KCNJ1 KCNJ1 KCNF1 KCNF1 KCNC3 KCNC3 KCNS2 KCNS2 GNB3 GNB3 KCNK9 KCNK9 KCNMB3 KCNMB3 KCNH2 KCNH2 KCNJ4 KCNJ4 GNB2 GNB2 KCNJ14 KCNJ14 KCNS3 KCNS3 KCNK3 KCNK3 Kcnj12 Kcnj12 KCNQ1 KCNQ1 KCNA3 KCNA3 KCNN3 KCNN3 HCN1 HCN1 Kcnj13 Kcnj13 Kcnmb2 Kcnmb2 Kcnk7 Kcnk7 GNB5 GNB5 PRR11 PRR11 KCNC4 KCNC4 KCNG3 KCNG3 KCND2 KCND2 KCNJ8 KCNJ8 KCNC1 KCNC1 KCNH3 KCNH3 KCNJ6 KCNJ6 GNG13 GNG13 KCNQ3 KCNQ3 GNGT1 GNGT1 GABBR2 GABBR2 GNB1 GNB1 KCNV1 KCNV1 H0V4J9_CAVPO H0V4J9_CAVPO KCNQ4 KCNQ4 KCNAB1 KCNAB1 KCNA1 KCNA1 KCNK18 KCNK18 KCNC2 KCNC2 KCNH1 KCNH1 KCNAB2 KCNAB2 KCNK10 KCNK10 KCNAB3 KCNAB3 ATPSCKMT ATPSCKMT KCNH5 KCNH5 KCNA10 KCNA10 KCND3 KCND3 KCNH6 KCNH6 ABCC8 ABCC8 KCNK1 KCNK1 KCNN4 KCNN4 ANTKMT ANTKMT KCNB2 KCNB2 KCNN2 KCNN2 KCNQ5 KCNQ5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Kcng2Ion_trans domain-containing protein; Belongs to the potassium channel family. (235 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (855 aa)
KCNV2Potassium voltage-gated channel modifier subfamily V member 2; Belongs to the potassium channel family. (558 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
KCNJ16Inwardly-rectifying potassium channel Kir5.1. (419 aa)
ENSCPOP00000030509Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ABCC9ATP binding cassette subfamily C member 9. (1546 aa)
Kcnj2Inward rectifier potassium channel 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Blocked b [...] (427 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
KCND1Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (651 aa)
ENSCPOP00000031524Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (100 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
KCNA7Potassium voltage-gated channel subfamily A member 7; Belongs to the potassium channel family. (469 aa)
Kcnj3IRK_C domain-containing protein. (194 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
KCNA4Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family. (622 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1133 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
Gng5G protein gamma domain-containing protein. (41 aa)
KCNJ10Potassium voltage-gated channel subfamily J member 10. (379 aa)
KCNG4Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family. (509 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
KCNQ2Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. (871 aa)
GNB4G protein subunit beta 4. (340 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
KCNH8Potassium voltage-gated channel subfamily H member 8. (1107 aa)
Kcnk6Potassium channel subfamily K member. (312 aa)
KCNK16Potassium two pore domain channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (300 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
KCNG1Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family. (515 aa)
KCNS1Potassium voltage-gated channel modifier subfamily S member 1; Belongs to the potassium channel family. (497 aa)
KCNA6Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family. (491 aa)
KCNK13Potassium two pore domain channel subfamily K member 13; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (405 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
KCNJ15ATP-sensitive inward rectifier potassium channel 15; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium (By similarity). (421 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (844 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (783 aa)
KCNH7Potassium voltage-gated channel subfamily H member 7. (1173 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1186 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (392 aa)
H0WBW4_CAVPOGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
KCNJ11ATP-sensitive inward rectifier potassium channel 11; This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Can form cardiac and smo [...] (390 aa)
KCNH4Potassium voltage-gated channel subfamily H member 4. (977 aa)
GPR156G protein-coupled receptor 156. (788 aa)
KCNK4Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (392 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (609 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (780 aa)
KCNN1Potassium calcium-activated channel subfamily N member 1. (558 aa)
KCNJ1Potassium voltage-gated channel subfamily J member 1. (376 aa)
KCNF1Potassium voltage-gated channel modifier subfamily F member 1; Belongs to the potassium channel family. (435 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (729 aa)
KCNS2Potassium voltage-gated channel modifier subfamily S member 2; Belongs to the potassium channel family. (445 aa)
GNB3G protein subunit beta 3. (340 aa)
KCNK9Potassium channel subfamily K member 9; pH-dependent, voltage-insensitive, background potassium channel protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (365 aa)
KCNMB3Potassium calcium-activated channel subfamily M regulatory beta subunit 3. (270 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (By similarity). (1144 aa)
KCNJ4Uncharacterized protein. (443 aa)
GNB2G protein subunit beta 2. (378 aa)
KCNJ14Inwardly-rectifying potassium channel Kir2.4. (439 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
KCNK3Potassium two pore domain channel subfamily K member 3. (270 aa)
Kcnj12Uncharacterized protein. (535 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] (671 aa)
KCNA3Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family. (528 aa)
KCNN3Potassium calcium-activated channel subfamily N member 3. (720 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (671 aa)
Kcnj13Inward rectifier potassium channel 13; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependen [...] (352 aa)
Kcnmb2KcnmB2_inactiv domain-containing protein. (235 aa)
Kcnk7Potassium channel subfamily K member. (315 aa)
GNB5G protein subunit beta 5. (406 aa)
PRR11Proline rich 11. (358 aa)
KCNC4Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (594 aa)
KCNG3Potassium voltage-gated channel modifier subfamily G member 3; Belongs to the potassium channel family. (417 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
KCNJ8Uncharacterized protein. (468 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
KCNH3Potassium voltage-gated channel subfamily H member 3. (1085 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (429 aa)
GNG13G protein subunit gamma 13. (67 aa)
KCNQ3Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. (860 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (820 aa)
GNB1Beta-transducin. (340 aa)
KCNV1Potassium voltage-gated channel modifier subfamily V member 1; Belongs to the potassium channel family. (502 aa)
H0V4J9_CAVPOUncharacterized protein. (291 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (699 aa)
KCNAB1Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (401 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
KCNK18Potassium two pore domain channel subfamily K member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (384 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (418 aa)
KCNH1Uncharacterized protein. (989 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (382 aa)
KCNK10Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (535 aa)
KCNAB3Potassium voltage-gated channel subfamily A regulatory beta subunit 3. (404 aa)
ATPSCKMTATP synthase c subunit lysine N-methyltransferase. (210 aa)
KCNH5Potassium voltage-gated channel subfamily H member 5. (989 aa)
KCNA10Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family. (511 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (654 aa)
KCNH6Potassium voltage-gated channel subfamily H member 6. (916 aa)
ABCC8ATP binding cassette subfamily C member 8. (1549 aa)
KCNK1Potassium channel subfamily K member 1; Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but also in kidney and in other tissues. Forms dimeric channels through which potassium ions pass in accordance with their electrochemical gradient. The channel is selective for K(+) ions at physiological potassium concentrations and at neutral pH, but becomes permeable to Na(+) at subphysiological K(+) levels and upon acidification of the extracellular medium. The homodimer has very low potassium [...] (336 aa)
KCNN4Intermediate-conductance calcium-activated potassium channel. (427 aa)
ANTKMTAdenine nucleotide translocase lysine methyltransferase. (232 aa)
KCNB2Potassium voltage-gated channel subfamily B member 2; Belongs to the potassium channel family. (911 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (842 aa)
KCNQ5Potassium voltage-gated channel subfamily Q member 5. (908 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: medium (42%) [HD]