STRINGSTRING
MAMLD1 MAMLD1 YWHAZ YWHAZ AKT1 AKT1 HEYL HEYL IKZF3 IKZF3 ENSCPOP00000027243 ENSCPOP00000027243 HEY1 HEY1 WWP2 WWP2 ELF3 ELF3 TACC3 TACC3 PBX3 PBX3 PSENEN PSENEN ENSCPOP00000029508 ENSCPOP00000029508 UBB UBB ENSCPOP00000031632 ENSCPOP00000031632 Ubc Ubc JAG1 JAG1 EGFR EGFR LOC100730084 LOC100730084 UBA52 UBA52 Notch4 Notch4 EGF EGF DTX4 DTX4 PSEN2 PSEN2 POFUT1 POFUT1 TMED2 TMED2 NBEA NBEA APH1B APH1B MIB1 MIB1 EP300 EP300 Rps27a Rps27a PBX1 PBX1 APH1A APH1A NEURL1 NEURL1 LRBA LRBA JAG2 JAG2 MAML2 MAML2 POGLUT1 POGLUT1 CNTN1 CNTN1 IKZF4 IKZF4 H0VFY3_CAVPO H0VFY3_CAVPO ADAM10 ADAM10 YBX1 YBX1 DLL4 DLL4 DNER DNER H0VKD6_CAVPO H0VKD6_CAVPO NOTCH1 NOTCH1 IKZF2 IKZF2 ITCH ITCH MOV10 MOV10 NCSTN NCSTN NOTCH2 NOTCH2 DLK1 DLK1 MFNG MFNG H0VXJ3_CAVPO H0VXJ3_CAVPO NOTCH3 NOTCH3 DLL1 DLL1 PBX2 PBX2 H0WAD6_CAVPO H0WAD6_CAVPO HEY2 HEY2 RFNG RFNG H0WDT2_CAVPO H0WDT2_CAVPO HES1 HES1 EHF EHF Dtx2 Dtx2 IKZF1 IKZF1 HES5 HES5 ENSCPOP00000024615 ENSCPOP00000024615 PSEN1 PSEN1 NEURL1B NEURL1B DLGAP5 DLGAP5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAMLD1Mastermind like domain containing 1. (714 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
IKZF3IKAROS family zinc finger 3. (510 aa)
ENSCPOP00000027243Uncharacterized protein. (519 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
WWP2E3 ubiquitin-protein ligase. (870 aa)
ELF3E74 like ETS transcription factor 3. (372 aa)
TACC3TACC_C domain-containing protein. (783 aa)
PBX3PBX homeobox 3. (434 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
ENSCPOP00000029508C-type lectin domain-containing protein. (264 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
UbcUncharacterized protein. (159 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
EGFRReceptor protein-tyrosine kinase. (1214 aa)
LOC100730084Beta-1,3-N-acetylglucosaminyltransferase. (373 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
Notch4Uncharacterized protein. (1988 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1194 aa)
DTX4Deltex E3 ubiquitin ligase 4. (620 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
POFUT1Protein O-fucosyltransferase 1. (392 aa)
TMED2Transmembrane p24 trafficking protein 2. (208 aa)
NBEANeurobeachin. (2866 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (963 aa)
EP300E1A binding protein p300. (2425 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
PBX1PBX homeobox 1. (430 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
LRBALPS responsive beige-like anchor protein. (2861 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1095 aa)
MAML2Mastermind like transcriptional coactivator 2. (958 aa)
POGLUT1Protein O-glucosyltransferase 1. (392 aa)
CNTN1Contactin 1. (1018 aa)
IKZF4IKAROS family zinc finger 4. (653 aa)
H0VFY3_CAVPOUncharacterized protein. (674 aa)
ADAM10ADAM metallopeptidase domain 10. (679 aa)
YBX1YB1. (324 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
DNERDelta/notch like EGF repeat containing. (741 aa)
H0VKD6_CAVPOUncharacterized protein. (184 aa)
NOTCH1Notch receptor 1. (2472 aa)
IKZF2IKAROS family zinc finger 2. (531 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
MOV10Mov10 RISC complex RNA helicase. (1063 aa)
NCSTNNicastrin. (709 aa)
NOTCH2Notch receptor 2. (2455 aa)
DLK1Delta like non-canonical Notch ligand 1. (362 aa)
MFNGMFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (199 aa)
H0VXJ3_CAVPOUncharacterized protein. (345 aa)
NOTCH3Notch receptor 3. (2141 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (607 aa)
PBX2PBX homeobox 2. (430 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (333 aa)
RFNGBeta-1,3-N-acetylglucosaminyltransferase. (320 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
HES1Hes family bHLH transcription factor 1. (279 aa)
EHFETS homologous factor. (300 aa)
Dtx2Uncharacterized protein. (619 aa)
IKZF1IKAROS family zinc finger 1. (511 aa)
HES5Hes family bHLH transcription factor 5. (164 aa)
ENSCPOP00000024615Bromo domain-containing protein. (84 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
NEURL1BNeuralized E3 ubiquitin protein ligase 1B. (315 aa)
DLGAP5DLG associated protein 5. (815 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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