72 items (Cavia porcellus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	INPP4B	Inositol polyphosphate-4-phosphatase type II B. (939 aa)
	PIK3C2A	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1404 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1018 aa)
	SASH3	SAM and SH3 domain containing 3. (380 aa)
	PIP5K1C	Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (689 aa)
	RUBCN	Rubicon autophagy regulator. (954 aa)
	PIP5K1A	Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (536 aa)
	MTMR3	Myotubularin related protein 3. (1221 aa)
	PIK3R6	Phosphoinositide-3-kinase regulatory subunit 6. (763 aa)
	PLEKHA3	Pleckstrin homology domain containing A3. (300 aa)
	PIP5K1B	Phosphatidylinositol-4-phosphate 5-kinase type 1 beta. (488 aa)
	PI4K2A	PI3K/PI4K domain-containing protein. (479 aa)
	RUNDC3B	RUN domain containing 3B. (400 aa)
	PLEKHA8	Pleckstrin homology domain containing A8. (519 aa)
	RAB5A	RAB5A, member RAS oncogene family. (214 aa)
	LOC100725517	Myotubularin phosphatase domain-containing protein. (355 aa)
	PIP4K2B	Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (362 aa)
	PIK3C2B	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1633 aa)
	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1. (365 aa)
	RUFY2	RUN and FYVE domain containing 2. (585 aa)
	PIK3CA	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1044 aa)
	RUFY3	RUN and FYVE domain containing 3. (628 aa)
	INPP5K	Inositol polyphosphate-5-phosphatase K. (461 aa)
	PTPN13	Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. (2480 aa)
	MTMR6	Myotubularin related protein 6. (620 aa)
	PIP4K2A	Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (398 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	H0VB67_CAVPO	Phosphatidylinositol 3-kinase catalytic subunit type 3. (651 aa)
	PLEKHA4	Pleckstrin homology domain containing A4. (777 aa)
	INSC	INSC spindle orientation adaptor protein. (532 aa)
	PIK3R5	Phosphoinositide-3-kinase regulatory subunit 5. (886 aa)
	MTMR14	Myotubularin related protein 14. (649 aa)
	PLEKHA6	Pleckstrin homology domain containing A6. (1174 aa)
	RUFY1	RUN and FYVE domain containing 1. (694 aa)
	INPP5J	Inositol polyphosphate-5-phosphatase J. (1015 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
	OCRL	OCRL inositol polyphosphate-5-phosphatase. (900 aa)
	BMX	Tyrosine-protein kinase. (655 aa)
	PIP4K2C	Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (419 aa)
	MFSD6L	Major facilitator superfamily domain containing 6 like. (584 aa)
	H0W027_CAVPO	Uncharacterized protein. (722 aa)
	H0W3F4_CAVPO	Myotubularin phosphatase domain-containing protein. (121 aa)
	SNX29	Sorting nexin 29. (787 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (355 aa)
	RUNDC3A	RUN domain containing 3A. (437 aa)
	SASH1	SAM and SH3 domain containing 1. (1232 aa)
	SYNJ1	Synaptojanin 1. (1607 aa)
	FAM102B	Family with sequence similarity 102 member B. (360 aa)
	PI4K2B	Phosphatidylinositol 4-kinase type 2 beta. (469 aa)
	MTMR9	Myotubularin related protein 9. (549 aa)
	PLEKHA7	Pleckstrin homology domain containing A7. (1252 aa)
	PLEKHA2	Pleckstrin homology domain containing A2. (425 aa)
	PSORS1C2	Psoriasis susceptibility 1 candidate 2. (138 aa)
	PLEKHA5	Pleckstrin homology domain containing A5. (1260 aa)
	INPP4A	Inositol polyphosphate-4-phosphatase type I A. (972 aa)
	MTM1	Myotubularin 1. (599 aa)
	PIP5KL1	Phosphatidylinositol-4-phosphate 5-kinase like 1. (423 aa)
	PLEKHM3	Pleckstrin homology domain containing M3. (759 aa)
	ENSCPOP00000030846	Uncharacterized protein. (170 aa)
	PLEKHA1	Pleckstrin homology domain containing A1. (402 aa)
	SAMD5	Sterile alpha motif domain containing 5. (171 aa)
	FAM102A	Family with sequence similarity 102 member A. (385 aa)
	SYNJ2	Synaptojanin 2. (1489 aa)
	LOC100734206	Uncharacterized protein. (461 aa)
	LOC101788042	C2 domain-containing protein. (110 aa)
	RAB14	RAB14, member RAS oncogene family. (215 aa)
	INPP5D	Inositol polyphosphate-5-phosphatase D. (1220 aa)
	ARF1	ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
	PIK3CG	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1092 aa)
	MFSD6	Major facilitator superfamily domain containing 6. (797 aa)
	RAB4A	RAB4A, member RAS oncogene family. (218 aa)
	INPPL1	Inositol polyphosphate phosphatase like 1. (1267 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARF1	H0VB67_CAVPO	ENSCPOP00000028546	ENSCPOP00000007134	ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.420
ARF1	OCRL	ENSCPOP00000028546	ENSCPOP00000012251	ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family.	OCRL inositol polyphosphate-5-phosphatase.	0.578
ARF1	PLEKHA3	ENSCPOP00000028546	ENSCPOP00000003525	ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family.	Pleckstrin homology domain containing A3.	0.675
ARF1	PLEKHA8	ENSCPOP00000028546	ENSCPOP00000004523	ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family.	Pleckstrin homology domain containing A8.	0.675
BMX	H0W027_CAVPO	ENSCPOP00000013551	ENSCPOP00000016311	Tyrosine-protein kinase.	Uncharacterized protein.	0.637
BMX	INPP5D	ENSCPOP00000013551	ENSCPOP00000029541	Tyrosine-protein kinase.	Inositol polyphosphate-5-phosphatase D.	0.455
BMX	INPPL1	ENSCPOP00000013551	ENSCPOP00000025833	Tyrosine-protein kinase.	Inositol polyphosphate phosphatase like 1.	0.679
BMX	LOC100734206	ENSCPOP00000013551	ENSCPOP00000030098	Tyrosine-protein kinase.	Uncharacterized protein.	0.637
BMX	PIK3CA	ENSCPOP00000013551	ENSCPOP00000005920	Tyrosine-protein kinase.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family.	0.759
BMX	PIK3CB	ENSCPOP00000013551	ENSCPOP00000000795	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.758
BMX	PIK3CD	ENSCPOP00000013551	ENSCPOP00000011659	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.786
BMX	PIK3CG	ENSCPOP00000013551	ENSCPOP00000027435	Tyrosine-protein kinase.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.	0.696
BMX	PIK3R1	ENSCPOP00000013551	ENSCPOP00000007043	Tyrosine-protein kinase.	Phosphoinositide-3-kinase regulatory subunit 1.	0.637
BMX	PIK3R5	ENSCPOP00000013551	ENSCPOP00000009005	Tyrosine-protein kinase.	Phosphoinositide-3-kinase regulatory subunit 5.	0.583
BMX	PTEN	ENSCPOP00000013551	ENSCPOP00000018437	Tyrosine-protein kinase.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.466
BMX	RUFY1	ENSCPOP00000013551	ENSCPOP00000010871	Tyrosine-protein kinase.	RUN and FYVE domain containing 1.	0.768
BMX	SASH3	ENSCPOP00000013551	ENSCPOP00000001133	Tyrosine-protein kinase.	SAM and SH3 domain containing 3.	0.457
ENSCPOP00000030846	H0VB67_CAVPO	ENSCPOP00000030846	ENSCPOP00000007134	Uncharacterized protein.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.420
ENSCPOP00000030846	OCRL	ENSCPOP00000030846	ENSCPOP00000012251	Uncharacterized protein.	OCRL inositol polyphosphate-5-phosphatase.	0.578
ENSCPOP00000030846	PLEKHA3	ENSCPOP00000030846	ENSCPOP00000003525	Uncharacterized protein.	Pleckstrin homology domain containing A3.	0.675