STRINGSTRING
MAP3K20 MAP3K20 TRAF6 TRAF6 TAB3 TAB3 AAMP AAMP UBA52 UBA52 NOD1 NOD1 MAP3K7 MAP3K7 CASP2 CASP2 CASP12 CASP12 ENSCPOP00000027005 ENSCPOP00000027005 ENSCPOP00000029546 ENSCPOP00000029546 UBB UBB CASP8 CASP8 Rps27a Rps27a ENSCPOP00000030838 ENSCPOP00000030838 ENSCPOP00000031632 ENSCPOP00000031632 Ubc Ubc NOD2 NOD2 MAPK11 MAPK11 ENSCPOP00000023362 ENSCPOP00000023362 BIRC3 BIRC3 MAPK14 MAPK14 MAP2K6 MAP2K6 LOC100725217 LOC100725217 H0WDT2_CAVPO H0WDT2_CAVPO TAB1 TAB1 IKBKG IKBKG H0WAD6_CAVPO H0WAD6_CAVPO BIRC7 BIRC7 CASP10 CASP10 TAB2 TAB2 MAPK12 MAPK12 MAPK13 MAPK13 UBE2V1 UBE2V1 ITCH ITCH LOC106026468 LOC106026468 CASP9 CASP9 H0VK31_CAVPO H0VK31_CAVPO TNFAIP3 TNFAIP3 BIRC2 BIRC2 CYLD CYLD H0VET0_CAVPO H0VET0_CAVPO LOC100731744 LOC100731744 RIPK2 RIPK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (711 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (679 aa)
AAMPAngio associated migratory cell protein. (436 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (873 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
CASP12Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (400 aa)
ENSCPOP00000027005UBIQUITIN_CONJUGAT_2 domain-containing protein. (83 aa)
ENSCPOP00000029546UBIQUITIN_CONJUGAT_2 domain-containing protein. (140 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (481 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
ENSCPOP00000030838UBIQUITIN_CONJUGAT_2 domain-containing protein. (133 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
UbcUncharacterized protein. (159 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1018 aa)
MAPK11Mitogen-activated protein kinase. (385 aa)
ENSCPOP00000023362UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
BIRC3Baculoviral IAP repeat containing 3. (600 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
LOC100725217Uncharacterized protein; Belongs to the peptidase C14A family. (361 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (507 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (416 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
BIRC7Baculoviral IAP repeat containing 7. (272 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (474 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (665 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
UBE2V1Ubiquitin conjugating enzyme E2 V1. (145 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
LOC106026468UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (174 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (447 aa)
H0VK31_CAVPOUncharacterized protein; Belongs to the peptidase C14A family. (365 aa)
TNFAIP3TNF alpha induced protein 3. (789 aa)
BIRC2Baculoviral IAP repeat containing 2. (615 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
H0VET0_CAVPOUncharacterized protein; Belongs to the peptidase C14A family. (204 aa)
LOC100731744NACHT domain-containing protein. (1402 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (442 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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