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| | Rps27a | Ubiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa) |
| | GSDMD | Gasdermin D. (481 aa) |
| | MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | FNBP4 | Formin binding protein 4. (1044 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | Usp18 | USP domain-containing protein; Belongs to the peptidase C19 family. (158 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (377 aa) |
| | CD180 | CD180 molecule. (645 aa) |
| | IRAK2 | Interleukin 1 receptor associated kinase 2. (606 aa) |
| | LGMN | Legumain. (436 aa) |
| | PPP4R1 | Protein phosphatase 4 regulatory subunit 1. (942 aa) |
| | LRRC71 | Leucine rich repeat containing 71. (548 aa) |
| | VWC2 | Von Willebrand factor C domain containing 2. (315 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (679 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa) |
| | NFKB2 | Nuclear factor kappa B subunit 2. (854 aa) |
| | APOB | Apolipoprotein B. (4479 aa) |
| | TLR6 | Toll like receptor 6; Belongs to the Toll-like receptor family. (796 aa) |
| | CNPY4 | Canopy FGF signaling regulator 4. (250 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (308 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | RIPK2 | Receptor interacting serine/threonine kinase 2. (442 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (684 aa) |
| | DUSP7 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa) |
| | LOC100731744 | NACHT domain-containing protein. (1402 aa) |
| | SFTPD | Surfactant protein D. (347 aa) |
| | PIK3R4 | Phosphoinositide-3-kinase regulatory subunit 4. (1354 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (967 aa) |
| | ALPK1 | Alpha kinase 1. (1117 aa) |
| | LOC100734047 | Uncharacterized protein. (567 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa) |
| | CTSB | Cathepsin B; Belongs to the peptidase C1 family. (340 aa) |
| | ELK1 | ETS transcription factor ELK1. (422 aa) |
| | CTSV | Cathepsin V; Belongs to the peptidase C1 family. (333 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (739 aa) |
| | CTSS | Cathepsin S; Belongs to the peptidase C1 family. (268 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (594 aa) |
| | NLRC5 | NLR family CARD domain containing 5. (1831 aa) |
| | LRRC74A | Leucine rich repeat containing 74A. (465 aa) |
| | LRRC34 | Leucine rich repeat containing 34. (448 aa) |
| | LY86 | Lymphocyte antigen 86. (162 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (325 aa) |
| | LOC106026468 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (174 aa) |
| | NFKBIB | NFKB inhibitor beta. (355 aa) |
| | MAPK15 | Mitogen-activated protein kinase. (539 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (588 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (461 aa) |
| | LRRC45 | Leucine rich repeat containing 45. (669 aa) |
| | PPP4R4 | Protein phosphatase 4 regulatory subunit 4. (832 aa) |
| | UBE2V1 | Ubiquitin conjugating enzyme E2 V1. (145 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (386 aa) |
| | BPIFC | BPI fold containing family C. (508 aa) |
| | EEA1 | Early endosome antigen 1. (1377 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (665 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1370 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase. (835 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (837 aa) |
| | RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1097 aa) |
| | TANK | TRAF family member associated NFKB activator. (419 aa) |
| | TLR10 | Toll like receptor 10; Belongs to the Toll-like receptor family. (777 aa) |
| | LRRC14 | Leucine rich repeat containing 14. (493 aa) |
| | GSDME | Gasdermin E. (498 aa) |
| | CASP10 | Caspase 10; Belongs to the peptidase C14A family. (474 aa) |
| | LOC100727376 | C-type lectin domain-containing protein. (240 aa) |
| | CNPY3 | Canopy FGF signaling regulator 3. (274 aa) |
| | IRF3 | Interferon regulatory factor 3. (389 aa) |
| | MAPKAPK2 | MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (383 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (459 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (549 aa) |
| | ECSIT | ECSIT signalling integrator. (431 aa) |
| | TIRAP | TIR domain containing adaptor protein. (221 aa) |
| | H0W160_CAVPO | Uncharacterized protein. (589 aa) |
| | SARM1 | Sterile alpha and TIR motif containing 1. (752 aa) |
| | N4BP1 | NEDD4 binding protein 1. (886 aa) |
| | TLR8 | Toll like receptor 8; Belongs to the Toll-like receptor family. (1035 aa) |
| | VRK3 | VRK serine/threonine kinase 3. (402 aa) |
| | BIRC7 | Baculoviral IAP repeat containing 7. (272 aa) |
| | KHNYN | KH and NYN domain containing. (657 aa) |
| | CD14 | CD14 molecule. (395 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (797 aa) |
| | H0WAD6_CAVPO | Ubiquitin-like domain-containing protein. (111 aa) |
| | TLR2 | Toll like receptor 2; Belongs to the Toll-like receptor family. (782 aa) |
| | H0WAS6_CAVPO | Uncharacterized protein. (214 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (416 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (507 aa) |
| | APP | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (770 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (253 aa) |
| | H0WDT2_CAVPO | Ubiquitin-like domain-containing protein. (127 aa) |
| | UBE2D1 | Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (139 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | MAPKAPK3 | MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (380 aa) |
| | LOC100718750 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (133 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (565 aa) |
| | RBSN | Rabenosyn, RAB effector. (789 aa) |
| | LBP | Lipopolysaccharide binding protein. (480 aa) |
| | SFTPA1 | Pulmonary surfactant-associated protein A; In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air- liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages; Belongs to the SFTPA family. (247 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | RPS6KA2 | Ribosomal protein S6 kinase. (733 aa) |
| | RPS6KA3 | Ribosomal protein S6 kinase. (740 aa) |
| | RPS6KA1 | Ribosomal protein S6 kinase. (744 aa) |
| | ENSCPOP00000023362 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) |
| | USP14 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (493 aa) |
| | Hmgb1 | annotation not available (215 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (385 aa) |
| | DUSP6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | NKIRAS1 | NFKB inhibitor interacting Ras like 1. (192 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (873 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (696 aa) |
| | SIGIRR | Single Ig and TIR domain containing. (408 aa) |
| | FOSL2 | FOS like 2, AP-1 transcription factor subunit. (325 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | CD36 | CD36 molecule; Belongs to the CD36 family. (472 aa) |
| | LOC100724130 | TIR domain-containing protein. (1029 aa) |
| | Atf7 | Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (411 aa) |
| | IRF7 | Interferon regulatory factor 7. (441 aa) |
| | TLR3 | Toll-like receptor 3; Belongs to the Toll-like receptor family. (905 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | DUSP4 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (393 aa) |
| | S100B | Protein S100; Belongs to the S-100 family. (92 aa) |
| | TIFA | TRAF interacting protein with forkhead associated domain. (185 aa) |
| | ENSCPOP00000027005 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (83 aa) |
| | S100A1 | Protein S100; Belongs to the S-100 family. (94 aa) |
| | Ticam2 | TIR domain-containing protein. (228 aa) |
| | LRRC74B | Leucine rich repeat containing 74B. (380 aa) |
| | HSP90B1 | Heat shock protein 90 beta family member 1. (807 aa) |
| | LY96 | Lymphocyte antigen 96. (159 aa) |
| | TLR1 | Toll like receptor 1; Belongs to the Toll-like receptor family. (818 aa) |
| | TLR7 | Toll like receptor 7. (1049 aa) |
| | NLRX1 | NLR family member X1. (976 aa) |
| | ENSCPOP00000029546 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (140 aa) |
| | UBB | Polyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa) |
| | PELI3 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (445 aa) |
| | CTSK | Cathepsin K; Belongs to the peptidase C1 family. (329 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (481 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa) |
| | ATF1 | Activating transcription factor 1. (269 aa) |
| | MAP3K20 | Mitogen-activated protein kinase kinase kinase 20. (711 aa) |
| | ENSCPOP00000030838 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (133 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | NKIRAS2 | NFKB inhibitor interacting Ras like 2. (191 aa) |
| | Dusp3 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa) |
| | UNC93A | Unc-93 homolog A. (428 aa) |
| | ENSCPOP00000031632 | Ubiquitin-like domain-containing protein. (141 aa) |
| | Ubc | Uncharacterized protein. (159 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (749 aa) |
| | ENSCPOP00000032088 | Uncharacterized protein. (191 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (707 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1018 aa) |
| | PELI2 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (420 aa) |
| | PTPN4 | Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (914 aa) |
| | UNC93B1 | Unc-93 homolog B1, TLR signaling regulator. (614 aa) |
| | TONSL | Tonsoku like, DNA repair protein. (1395 aa) |
| | UBE2D2 | Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | MAPK10 | Mitogen-activated protein kinase 10. (434 aa) |
