STRINGSTRING
BTRC BTRC ENSCPOP00000030888 ENSCPOP00000030888 PLK1 PLK1 CDC27 CDC27 Cdk1 Cdk1 ANAPC15 ANAPC15 ENSCPOP00000031632 ENSCPOP00000031632 SKP1 SKP1 UBE2E1 UBE2E1 CCNA2 CCNA2 MAD2L1 MAD2L1 Ubc Ubc FZR1 FZR1 BUB3 BUB3 CDC20B CDC20B CDC26 CDC26 ANAPC16 ANAPC16 ANAPC1 ANAPC1 ENSCPOP00000029129 ENSCPOP00000029129 ENSCPOP00000029251 ENSCPOP00000029251 ANAPC4 ANAPC4 UBE2S UBE2S ANAPC5 ANAPC5 FBXO43 FBXO43 UBA52 UBA52 FAM89B FAM89B CDC16 CDC16 UBB UBB CDC23 CDC23 CDK2 CDK2 ANAPC10 ANAPC10 ANAPC2 ANAPC2 Bub1b Bub1b FBXO5 FBXO5 CDC20 CDC20 Rps27a Rps27a Anapc11 Anapc11 TM7SF3 TM7SF3 ANAPC7 ANAPC7 H0VZC1_CAVPO H0VZC1_CAVPO CUL1 CUL1 H0WAD6_CAVPO H0WAD6_CAVPO H0WDT2_CAVPO H0WDT2_CAVPO UBE2D1 UBE2D1 CCNA1 CCNA1 UBE2C UBE2C FAM89A FAM89A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (582 aa)
ENSCPOP00000030888Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (238 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
CDC27Cell division cycle 27. (825 aa)
Cdk1Protein kinase domain-containing protein. (240 aa)
ANAPC15Anaphase promoting complex subunit 15. (134 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
SKP1S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...] (162 aa)
UBE2E1Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (429 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
UbcUncharacterized protein. (159 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
BUB3BUB3 mitotic checkpoint protein. (326 aa)
CDC20BCell division cycle 20B. (525 aa)
CDC26Cell division cycle 26. (85 aa)
ANAPC16Anaphase promoting complex subunit 16. (118 aa)
ANAPC1Anaphase promoting complex subunit 1. (1941 aa)
ENSCPOP00000029129Protein kinase domain-containing protein. (254 aa)
ENSCPOP00000029251Uncharacterized protein; Belongs to the SKP1 family. (147 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (214 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
FBXO43F-box protein 43. (622 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
FAM89BFamily with sequence similarity 89 member B. (189 aa)
CDC16Cell division cycle 16. (620 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
CDC23Cell division cycle 23. (597 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (827 aa)
Bub1bUncharacterized protein. (1043 aa)
FBXO5F-box protein 5. (450 aa)
CDC20Cell division cycle 20. (499 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
Anapc11RING-type domain-containing protein. (84 aa)
TM7SF3Transmembrane 7 superfamily member 3. (570 aa)
ANAPC7Anaphase promoting complex subunit 7. (555 aa)
H0VZC1_CAVPOUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (199 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (139 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (420 aa)
UBE2CUbiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
FAM89AFamily with sequence similarity 89 member A. (174 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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