STRINGSTRING
CDC16 CDC16 PSME3 PSME3 Psma2 Psma2 Ubc Ubc PSME2 PSME2 MAD2L1 MAD2L1 ENSCPOP00000031632 ENSCPOP00000031632 PSMC1 PSMC1 ANAPC15 ANAPC15 CDC27 CDC27 Pttg1 Pttg1 PLK1 PLK1 ENSCPOP00000030888 ENSCPOP00000030888 UBB UBB FAM89B FAM89B PSMA6 PSMA6 PSMB2 PSMB2 PSMD12 PSMD12 ENSCPOP00000029129 ENSCPOP00000029129 ANAPC1 ANAPC1 ANAPC16 ANAPC16 PSMD4 PSMD4 PSMD14 PSMD14 CDC26 CDC26 PSMD2 PSMD2 CDC20B CDC20B PSMC3 PSMC3 BUB3 BUB3 PSME1 PSME1 ENSCPOP00000023065 ENSCPOP00000023065 ANAPC10 ANAPC10 PSMA3 PSMA3 FAM89A FAM89A PSMD1 PSMD1 UBE2C UBE2C CCNA1 CCNA1 UBE2D1 UBE2D1 H0WDT2_CAVPO H0WDT2_CAVPO PSMB10 PSMB10 H0WAD6_CAVPO H0WAD6_CAVPO PSMD5 PSMD5 PSMB11 PSMB11 PSMB3 PSMB3 PSMA4 PSMA4 Psmd9 Psmd9 H0VZC1_CAVPO H0VZC1_CAVPO H0VWS1_CAVPO H0VWS1_CAVPO PSMC2 PSMC2 ANAPC7 ANAPC7 PSMA1 PSMA1 PSMB4 PSMB4 PSMD3 PSMD3 Psmd10 Psmd10 TM7SF3 TM7SF3 PSMA7 PSMA7 PSMB5 PSMB5 PSMF1 PSMF1 Anapc11 Anapc11 PSMA5 PSMA5 ANAPC4 ANAPC4 UBE2S UBE2S PSMA8 PSMA8 PSME4 PSME4 ANAPC5 ANAPC5 PSMC5 PSMC5 NEK2 NEK2 PSMD7 PSMD7 PSMD8 PSMD8 CDC23 CDC23 CCNA2 CCNA2 PSMD11 PSMD11 ANAPC2 ANAPC2 PSMC6 PSMC6 Bub1b Bub1b PSMB7 PSMB7 PSMD6 PSMD6 CDC20 CDC20 Rps27a Rps27a Cdk1 Cdk1 PSMC4 PSMC4 PSMD13 PSMD13 UBE2E1 UBE2E1 PSMB9 PSMB9 PSMB6 PSMB6 PSMB1 PSMB1 PSMB8 PSMB8 UBA52 UBA52
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDC16Cell division cycle 16. (620 aa)
PSME3Proteasome activator subunit 3. (254 aa)
Psma2Proteasome subunit alpha type. (234 aa)
UbcUncharacterized protein. (159 aa)
PSME2Proteasome activator subunit 2. (239 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
ANAPC15Anaphase promoting complex subunit 15. (134 aa)
CDC27Cell division cycle 27. (825 aa)
Pttg1Uncharacterized protein. (198 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
ENSCPOP00000030888Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (238 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
FAM89BFamily with sequence similarity 89 member B. (189 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
ENSCPOP00000029129Protein kinase domain-containing protein. (254 aa)
ANAPC1Anaphase promoting complex subunit 1. (1941 aa)
ANAPC16Anaphase promoting complex subunit 16. (118 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (377 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
CDC26Cell division cycle 26. (85 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
CDC20BCell division cycle 20B. (525 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
BUB3BUB3 mitotic checkpoint protein. (326 aa)
PSME1Proteasome activator subunit 1. (249 aa)
ENSCPOP00000023065ANK_REP_REGION domain-containing protein. (179 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
FAM89AFamily with sequence similarity 89 member A. (174 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
UBE2CUbiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (420 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (139 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
PSMB10Proteasome subunit beta. (273 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PSMB11Proteasome subunit beta. (297 aa)
PSMB3Proteasome subunit beta. (207 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
Psmd9PDZ domain-containing protein. (223 aa)
H0VZC1_CAVPOUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (199 aa)
H0VWS1_CAVPOANK_REP_REGION domain-containing protein. (213 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (458 aa)
ANAPC7Anaphase promoting complex subunit 7. (555 aa)
PSMA1Proteasome subunit alpha type. (270 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (263 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
Psmd10ANK_REP_REGION domain-containing protein. (232 aa)
TM7SF3Transmembrane 7 superfamily member 3. (570 aa)
PSMA7Proteasome endopeptidase complex. (248 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
Anapc11RING-type domain-containing protein. (84 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (214 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PSME4Proteasome activator subunit 4. (1827 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
NEK2NIMA related kinase 2. (442 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
CDC23Cell division cycle 23. (597 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (429 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (827 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
Bub1bUncharacterized protein. (1043 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
CDC20Cell division cycle 20. (499 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
Cdk1Protein kinase domain-containing protein. (240 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (315 aa)
UBE2E1Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMB8Proteasome subunit beta. (273 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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