STRINGSTRING
LOC100717408 LOC100717408 C1QTNF5 C1QTNF5 Dhfr Dhfr Mthfs Mthfs MTHFD2 MTHFD2 Slc25a32 Slc25a32 SLC19A1 SLC19A1 FPGS FPGS SLC46A3 SLC46A3 MTHFD1 MTHFD1 SHMT2 SHMT2 ALDH1L2 ALDH1L2 MTHFD1L MTHFD1L ALDH1L1 ALDH1L1 SHMT1 SHMT1 SLC46A1 SLC46A1 MTHFR MTHFR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100717408Adiponectin F1. (333 aa)
C1QTNF5C1q and TNF related 5. (243 aa)
DhfrDHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
Mthfs5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (173 aa)
MTHFD2Uncharacterized protein. (350 aa)
Slc25a32Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa)
SLC19A1Solute carrier family 19 member 1. (506 aa)
FPGSFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (582 aa)
SLC46A3Solute carrier family 46 member 3. (461 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (928 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
ALDH1L210-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (923 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (901 aa)
ALDH1L110-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (902 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
SLC46A1Solute carrier family 46 member 1. (459 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (671 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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