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| | FNBP4 | Formin binding protein 4. (1044 aa) |
| | HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1194 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1018 aa) |
| | STRN4 | Striatin 4. (777 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (269 aa) |
| | PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1. (1249 aa) |
| | PPP4R1 | Protein phosphatase 4 regulatory subunit 1. (942 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (462 aa) |
| | PIP5K1C | Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (689 aa) |
| | CD19 | B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in [...] (536 aa) |
| | PIP5K1A | Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (536 aa) |
| | FRS2 | Fibroblast growth factor receptor substrate 2. (508 aa) |
| | FNDC3A | Fibronectin type III domain containing 3A. (1172 aa) |
| | PIP5K1B | Phosphatidylinositol-4-phosphate 5-kinase type 1 beta. (488 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa) |
| | KLB | Klotho beta. (1024 aa) |
| | TRAT1 | T cell receptor associated transmembrane adaptor 1. (187 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (308 aa) |
| | FGF2 | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (114 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | IRS1 | Insulin receptor substrate 1. (1243 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (362 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (257 aa) |
| | TRIB3 | Tribbles pseudokinase 3. (308 aa) |
| | IL33 | Interleukin 33. (280 aa) |
| | CD28 | CD28 molecule. (222 aa) |
| | ICOS | Inducible T cell costimulator. (199 aa) |
| | PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (190 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (707 aa) |
| | FAM102A | Family with sequence similarity 102 member A. (385 aa) |
| | LRRC40 | Leucine rich repeat containing 40. (591 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (801 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | IER3 | Immediate early response 3. (152 aa) |
| | PIP5KL1 | Phosphatidylinositol-4-phosphate 5-kinase like 1. (423 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | Fgf9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (91 aa) |
| | IL1RL1 | Interleukin 1 receptor like 1. (558 aa) |
| | LOC100734206 | Uncharacterized protein. (461 aa) |
| | EREG | Epiregulin. (164 aa) |
| | CD86 | CD86 molecule. (320 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (271 aa) |
| | CD276 | Uncharacterized protein. (628 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (801 aa) |
| | INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (801 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | AREG | Amphiregulin. (241 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (696 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | PPP2R5A | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (487 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | RAC1 | Ras-related C3 botulinum toxin substrate 1. (211 aa) |
| | WDR64 | WD repeat domain 64. (1056 aa) |
| | FAM102B | Family with sequence similarity 102 member B. (360 aa) |
| | BTC | Betacellulin. (183 aa) |
| | FLT3LG | Fms related tyrosine kinase 3 ligand. (179 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (294 aa) |
| | NRG4 | Neuregulin 4. (84 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (355 aa) |
| | ESR2 | Estrogen receptor 2. (568 aa) |
| | NRG2 | Neuregulin 2. (705 aa) |
| | H0W160_CAVPO | Uncharacterized protein. (589 aa) |
| | SPEM1 | Spermatid maturation 1. (307 aa) |
| | SPEM2 | SPEM family member 2. (483 aa) |
| | H0W027_CAVPO | Uncharacterized protein. (722 aa) |
| | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa) |
| | KL | Klotho. (760 aa) |
| | IL1RAP | Interleukin 1 receptor accessory protein. (685 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (308 aa) |
| | RAC2 | Ras-related C3 botulinum toxin substrate 2; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase (By similarity). (192 aa) |
| | RHOG | Ras homolog family member G. (191 aa) |
| | PIP4K2C | Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (419 aa) |
| | STRN3 | Striatin 3. (786 aa) |
| | AKT3 | AKT serine/threonine kinase 3. (470 aa) |
| | RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1097 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1336 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | PPP4R4 | Protein phosphatase 4 regulatory subunit 4. (832 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | EPGN | Epithelial mitogen. (133 aa) |
| | Bank1 | Uncharacterized protein. (497 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (588 aa) |
| | MET | MET proto-oncogene, receptor tyrosine kinase. (1380 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (325 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1371 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa) |
| | PIK3AP1 | Phosphoinositide-3-kinase adaptor protein 1. (832 aa) |
| | GAB2 | GRB2 associated binding protein 2. (635 aa) |
| | GAB1 | GRB2 associated binding protein 1. (751 aa) |
| | NRG3 | Neuregulin 3. (600 aa) |
| | STRN | Striatin. (780 aa) |
| | PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2. (1292 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | FNDC3B | Fibronectin type III domain containing 3B. (1101 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1263 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (594 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (180 aa) |
| | HBEGF | Heparin binding EGF like growth factor. (208 aa) |
| | TGFA | Transforming growth factor alpha. (159 aa) |
| | INSC | INSC spindle orientation adaptor protein. (532 aa) |
| | LOC100734047 | Uncharacterized protein. (567 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (596 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | NRG1 | Neuregulin 1. (700 aa) |
| | PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (398 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (235 aa) |
| | FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (987 aa) |
| | PIK3CA | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1044 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (822 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1102 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1256 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1214 aa) |
| | FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (160 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (589 aa) |
