14 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Ubc	Uncharacterized protein. (159 aa)
	ENSCPOP00000031632	Ubiquitin-like domain-containing protein. (141 aa)
	UBB	Polyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
	SQSTM1	Sequestosome 1. (415 aa)
	H0WDT2_CAVPO	Ubiquitin-like domain-containing protein. (127 aa)
	NGF	Beta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI. (308 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
	IRAK1	Interleukin 1 receptor associated kinase 1. (707 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa)
	Rps27a	Ubiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
	RIPK2	Receptor interacting serine/threonine kinase 2. (442 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (739 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (294 aa)
	H0WAD6_CAVPO	Ubiquitin-like domain-containing protein. (111 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCPOP00000031632	H0WDT2_CAVPO	ENSCPOP00000031632	ENSCPOP00000021155	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.977
ENSCPOP00000031632	IKBKB	ENSCPOP00000031632	ENSCPOP00000009478	Ubiquitin-like domain-containing protein.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.652
ENSCPOP00000031632	IRAK1	ENSCPOP00000031632	ENSCPOP00000032095	Ubiquitin-like domain-containing protein.	Interleukin 1 receptor associated kinase 1.	0.625
ENSCPOP00000031632	MYD88	ENSCPOP00000031632	ENSCPOP00000018802	Ubiquitin-like domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.639
ENSCPOP00000031632	RIPK2	ENSCPOP00000031632	ENSCPOP00000005780	Ubiquitin-like domain-containing protein.	Receptor interacting serine/threonine kinase 2.	0.550
ENSCPOP00000031632	SQSTM1	ENSCPOP00000031632	ENSCPOP00000023537	Ubiquitin-like domain-containing protein.	Sequestosome 1.	0.824
ENSCPOP00000031632	TRAF6	ENSCPOP00000031632	ENSCPOP00000004067	Ubiquitin-like domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.944
ENSCPOP00000031632	UBA52	ENSCPOP00000031632	ENSCPOP00000000308	Ubiquitin-like domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.977
ENSCPOP00000031632	UBB	ENSCPOP00000031632	ENSCPOP00000029946	Ubiquitin-like domain-containing protein.	Polyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...]	0.919
ENSCPOP00000031632	Ubc	ENSCPOP00000031632	ENSCPOP00000031925	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.914
H0WAD6_CAVPO	H0WDT2_CAVPO	ENSCPOP00000019948	ENSCPOP00000021155	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.977
H0WAD6_CAVPO	IKBKB	ENSCPOP00000019948	ENSCPOP00000009478	Ubiquitin-like domain-containing protein.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.652
H0WAD6_CAVPO	IRAK1	ENSCPOP00000019948	ENSCPOP00000032095	Ubiquitin-like domain-containing protein.	Interleukin 1 receptor associated kinase 1.	0.625
H0WAD6_CAVPO	MYD88	ENSCPOP00000019948	ENSCPOP00000018802	Ubiquitin-like domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.639
H0WAD6_CAVPO	RIPK2	ENSCPOP00000019948	ENSCPOP00000005780	Ubiquitin-like domain-containing protein.	Receptor interacting serine/threonine kinase 2.	0.550
H0WAD6_CAVPO	SQSTM1	ENSCPOP00000019948	ENSCPOP00000023537	Ubiquitin-like domain-containing protein.	Sequestosome 1.	0.824
H0WAD6_CAVPO	TRAF6	ENSCPOP00000019948	ENSCPOP00000004067	Ubiquitin-like domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.944
H0WAD6_CAVPO	UBA52	ENSCPOP00000019948	ENSCPOP00000000308	Ubiquitin-like domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.977
H0WAD6_CAVPO	UBB	ENSCPOP00000019948	ENSCPOP00000029946	Ubiquitin-like domain-containing protein.	Polyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...]	0.919
H0WAD6_CAVPO	Ubc	ENSCPOP00000019948	ENSCPOP00000031925	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.913