STRINGSTRING
MEN1 MEN1 RBL1 RBL1 UBA52 UBA52 CDK8 CDK8 CCNT2 CCNT2 UBB UBB CCNT1 CCNT1 CCNC CCNC PCSK4 PCSK4 SMAD4 SMAD4 Ubc Ubc ENSCPOP00000031632 ENSCPOP00000031632 SMAD3 SMAD3 E2F4 E2F4 Cdk9 Cdk9 Rps27a Rps27a RNF111 RNF111 FURIN FURIN SMAD7 SMAD7 MAPK3 MAPK3 CCNK CCNK CCNQ CCNQ H0VDT0_CAVPO H0VDT0_CAVPO TFDP2 TFDP2 H0WDT2_CAVPO H0WDT2_CAVPO H0WAD6_CAVPO H0WAD6_CAVPO H0W9U2_CAVPO H0W9U2_CAVPO SP1 SP1 JUNB JUNB TFDP1 TFDP1 SMAD2 SMAD2 MAPK1 MAPK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MEN1Menin 1. (615 aa)
RBL1RB transcriptional corepressor like 1. (1051 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
CDK8Cyclin dependent kinase 8; Belongs to the protein kinase superfamily. (449 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (734 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (727 aa)
CCNCCyclin C; Belongs to the cyclin family. (283 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (639 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
UbcUncharacterized protein. (159 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
E2F4E2F transcription factor 4. (411 aa)
Cdk9Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (372 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
RNF111Ring finger protein 111. (994 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (796 aa)
SMAD7SMAD family member 7. (221 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
CCNKCyclin K; Belongs to the cyclin family. (582 aa)
CCNQCyclin Q; Belongs to the cyclin family. (249 aa)
H0VDT0_CAVPOProtein kinase domain-containing protein. (337 aa)
TFDP2Transcription factor. (446 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
H0W9U2_CAVPOUncharacterized protein. (143 aa)
SP1Sp1 transcription factor. (786 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
TFDP1Transcription factor. (411 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
MAPK1Mitogen-activated protein kinase. (325 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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