STRINGSTRING
MAPK9 MAPK9 WDR92 WDR92 PPP3CA PPP3CA PPP3CB PPP3CB PIK3R1 PIK3R1 NFKB1 NFKB1 PIK3CA PIK3CA H0V789_CAVPO H0V789_CAVPO Rps27a Rps27a H0V4P2_CAVPO H0V4P2_CAVPO TRAF6 TRAF6 TAB3 TAB3 NFATC1 NFATC1 CARD11 CARD11 PDPK1 PDPK1 SOS1 SOS1 H0UY32_CAVPO H0UY32_CAVPO PLCG2 PLCG2 H0UWQ2_CAVPO H0UWQ2_CAVPO LOC100730263 LOC100730263 PIK3CB PIK3CB TRDC TRDC VAV3 VAV3 UBA52 UBA52 PAK1 PAK1 IKBKB IKBKB NRAS NRAS KRAS KRAS LYN LYN H0VK14_CAVPO H0VK14_CAVPO GAB2 GAB2 MS4A1 MS4A1 NFAT5 NFAT5 MALT1 MALT1 NFATC2 NFATC2 MAPK1 MAPK1 LOC106026468 LOC106026468 H0VN43_CAVPO H0VN43_CAVPO H0VNP1_CAVPO H0VNP1_CAVPO H0VQF0_CAVPO H0VQF0_CAVPO UBE2V1 UBE2V1 H0VR18_CAVPO H0VR18_CAVPO MAP2K4 MAP2K4 H0VRB7_CAVPO H0VRB7_CAVPO TXK TXK TAB2 TAB2 MAP3K1 MAP3K1 PLCG1 PLCG1 H0VZI8_CAVPO H0VZI8_CAVPO H0VZM4_CAVPO H0VZM4_CAVPO MAP2K7 MAP2K7 H0W027_CAVPO H0W027_CAVPO TRGC1 TRGC1 H0W320_CAVPO H0W320_CAVPO LAT2 LAT2 H0W4C0_CAVPO H0W4C0_CAVPO MS4A15 MS4A15 LAT LAT H0W6K2_CAVPO H0W6K2_CAVPO H0W6R6_CAVPO H0W6R6_CAVPO SHC1 SHC1 H0VUA1_CAVPO H0VUA1_CAVPO H0WAD6_CAVPO H0WAD6_CAVPO H0WAH0_CAVPO H0WAH0_CAVPO H0WAR2_CAVPO H0WAR2_CAVPO IKBKG IKBKG TAB1 TAB1 H0WCK1_CAVPO H0WCK1_CAVPO H0WDE0_CAVPO H0WDE0_CAVPO JUN JUN H0WDT2_CAVPO H0WDT2_CAVPO UBE2D1 UBE2D1 HARBI1 HARBI1 ENSCPOP00000021726 ENSCPOP00000021726 FOS FOS ENSCPOP00000022066 ENSCPOP00000022066 ENSCPOP00000022167 ENSCPOP00000022167 RAC1 RAC1 ENSCPOP00000022406 ENSCPOP00000022406 ENSCPOP00000022622 ENSCPOP00000022622 PAK2 PAK2 ENSCPOP00000022888 ENSCPOP00000022888 ENSCPOP00000023362 ENSCPOP00000023362 NFATC3 NFATC3 ENSCPOP00000023578 ENSCPOP00000023578 ENSCPOP00000023636 ENSCPOP00000023636 VAV2 VAV2 ENSCPOP00000023778 ENSCPOP00000023778 ENSCPOP00000023844 ENSCPOP00000023844 ENSCPOP00000023913 ENSCPOP00000023913 MAPK3 MAPK3 H0VVB6_CAVPO H0VVB6_CAVPO MAPK8 MAPK8 FCRL1 FCRL1 LOC106026778 LOC106026778 FOSL2 FOSL2 ENSCPOP00000025009 ENSCPOP00000025009 ENSCPOP00000025297 ENSCPOP00000025297 MAP3K7 MAP3K7 ENSCPOP00000025410 ENSCPOP00000025410 ENSCPOP00000025520 ENSCPOP00000025520 ENSCPOP00000025526 ENSCPOP00000025526 ENSCPOP00000025534 ENSCPOP00000025534 ENSCPOP00000025793 ENSCPOP00000025793 MS4A2 MS4A2 ENSCPOP00000025980 ENSCPOP00000025980 ENSCPOP00000026126 ENSCPOP00000026126 LCP2 LCP2 ENSCPOP00000026228 ENSCPOP00000026228 ENSCPOP00000026512 ENSCPOP00000026512 PRKCQ PRKCQ ENSCPOP00000027005 ENSCPOP00000027005 ENSCPOP00000027155 ENSCPOP00000027155 ENSCPOP00000027199 ENSCPOP00000027199 FCER1G FCER1G ENSCPOP00000028125 ENSCPOP00000028125 ENSCPOP00000028279 ENSCPOP00000028279 ENSCPOP00000028369 ENSCPOP00000028369 GRAP2 GRAP2 ENSCPOP00000028898 ENSCPOP00000028898 ENSCPOP00000028990 ENSCPOP00000028990 ENSCPOP00000029145 ENSCPOP00000029145 ENSCPOP00000029309 ENSCPOP00000029309 ENSCPOP00000029468 ENSCPOP00000029468 SPNS1 SPNS1 MAPK10 MAPK10 HRAS HRAS SPNS3 SPNS3 TEC TEC ENSCPOP00000032616 ENSCPOP00000032616 ENSCPOP00000032517 ENSCPOP00000032517 UBE2D2 UBE2D2 CHUK CHUK PPP3R1 PPP3R1 Ubc Ubc ENSCPOP00000031920 ENSCPOP00000031920 CSDE1 CSDE1 ENSCPOP00000031763 ENSCPOP00000031763 ENSCPOP00000031748 ENSCPOP00000031748 GRB2 GRB2 ENSCPOP00000031632 ENSCPOP00000031632 LOC106026776 LOC106026776 BCL10 BCL10 ENSCPOP00000031333 ENSCPOP00000031333 ENSCPOP00000031332 ENSCPOP00000031332 BTK BTK ENSCPOP00000031130 ENSCPOP00000031130 ENSCPOP00000030838 ENSCPOP00000030838 MAP3K20 MAP3K20 ENSCPOP00000030758 ENSCPOP00000030758 ENSCPOP00000030754 ENSCPOP00000030754 ENSCPOP00000030342 ENSCPOP00000030342 ENSCPOP00000030140 ENSCPOP00000030140 UBB UBB ENSCPOP00000029769 ENSCPOP00000029769 ENSCPOP00000029705 ENSCPOP00000029705 LOC100723205 LOC100723205 ENSCPOP00000029546 ENSCPOP00000029546 SYK SYK ITK ITK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK9Mitogen-activated protein kinase. (424 aa)
WDR92WD repeat domain 92. (357 aa)
PPP3CASerine/threonine-protein phosphatase. (518 aa)
PPP3CBSerine/threonine-protein phosphatase. (531 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
NFKB1Nuclear factor kappa B subunit 1. (967 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1044 aa)
H0V789_CAVPOIg-like domain-containing protein. (126 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
H0V4P2_CAVPOUncharacterized protein. (552 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (679 aa)
NFATC1Nuclear factor of activated T cells 1. (928 aa)
CARD11Caspase recruitment domain family member 11. (1158 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (550 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1276 aa)
H0UY32_CAVPOIg-like domain-containing protein. (123 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1270 aa)
H0UWQ2_CAVPOIg-like domain-containing protein. (212 aa)
LOC100730263Uncharacterized protein. (487 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1018 aa)
TRDCT cell receptor delta constant. (140 aa)
VAV3Vav guanine nucleotide exchange factor 3. (779 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (739 aa)
NRASGTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
LYNTyrosine-protein kinase. (512 aa)
H0VK14_CAVPOANK_REP_REGION domain-containing protein. (2289 aa)
GAB2GRB2 associated binding protein 2. (635 aa)
MS4A1Membrane spanning 4-domains A1. (298 aa)
NFAT5Nuclear factor of activated T cells 5. (1485 aa)
MALT1MALT1 paracaspase. (780 aa)
NFATC2Nuclear factor of activated T cells 2. (916 aa)
MAPK1Mitogen-activated protein kinase. (325 aa)
LOC106026468UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (174 aa)
H0VN43_CAVPOIg-like domain-containing protein. (124 aa)
H0VNP1_CAVPOIg-like domain-containing protein. (124 aa)
H0VQF0_CAVPOIg-like domain-containing protein. (123 aa)
UBE2V1Ubiquitin conjugating enzyme E2 V1. (145 aa)
H0VR18_CAVPOIg-like domain-containing protein. (136 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (386 aa)
H0VRB7_CAVPOIg-like domain-containing protein. (115 aa)
TXKTyrosine-protein kinase. (507 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (665 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1370 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1235 aa)
H0VZI8_CAVPOIg-like domain-containing protein. (123 aa)
H0VZM4_CAVPOIg-like domain-containing protein. (125 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (459 aa)
H0W027_CAVPOUncharacterized protein. (722 aa)
TRGC1Ig-like domain-containing protein. (166 aa)
H0W320_CAVPOIg-like domain-containing protein. (117 aa)
LAT2Linker for activation of T cells family member 2. (215 aa)
H0W4C0_CAVPOIg-like domain-containing protein. (119 aa)
MS4A15Membrane spanning 4-domains A15. (280 aa)
LATLinker for activation of T cells. (236 aa)
H0W6K2_CAVPOIg-like domain-containing protein. (135 aa)
H0W6R6_CAVPOIg-like domain-containing protein. (119 aa)
SHC1SHC adaptor protein 1. (583 aa)
H0VUA1_CAVPOIg-like domain-containing protein. (138 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
H0WAH0_CAVPOIg-like domain-containing protein. (121 aa)
H0WAR2_CAVPOIg-like domain-containing protein. (139 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (416 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (507 aa)
H0WCK1_CAVPOUncharacterized protein. (572 aa)
H0WDE0_CAVPOIg-like domain-containing protein. (118 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (253 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (139 aa)
HARBI1Harbinger transposase derived 1. (350 aa)
ENSCPOP00000021726Ig-like domain-containing protein. (123 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
ENSCPOP00000022066Ig-like domain-containing protein. (125 aa)
ENSCPOP00000022167Ig-like domain-containing protein. (174 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (211 aa)
ENSCPOP00000022406Ig-like domain-containing protein. (135 aa)
ENSCPOP00000022622Ig-like domain-containing protein. (129 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
ENSCPOP00000022888Uncharacterized protein. (124 aa)
ENSCPOP00000023362UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
NFATC3Nuclear factor of activated T cells 3. (1060 aa)
ENSCPOP00000023578Ig-like domain-containing protein. (129 aa)
ENSCPOP00000023636Ig-like domain-containing protein. (129 aa)
VAV2Vav guanine nucleotide exchange factor 2. (807 aa)
ENSCPOP00000023778Ig-like domain-containing protein. (179 aa)
ENSCPOP00000023844Ig-like domain-containing protein. (142 aa)
ENSCPOP00000023913Ig-like domain-containing protein. (122 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
H0VVB6_CAVPOIg-like domain-containing protein. (137 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
FCRL1Fc receptor like 1. (436 aa)
LOC106026778Uncharacterized protein. (129 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (325 aa)
ENSCPOP00000025009Ig-like domain-containing protein. (117 aa)
ENSCPOP00000025297Ig-like domain-containing protein. (131 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
ENSCPOP00000025410Ig-like domain-containing protein. (118 aa)
ENSCPOP00000025520Ig-like domain-containing protein. (129 aa)
ENSCPOP00000025526Ig-like domain-containing protein. (145 aa)
ENSCPOP00000025534Ig-like domain-containing protein. (118 aa)
ENSCPOP00000025793Ig-like domain-containing protein. (146 aa)
MS4A2Membrane spanning 4-domains A2. (242 aa)
ENSCPOP00000025980Ig-like domain-containing protein. (127 aa)
ENSCPOP00000026126Ig-like domain-containing protein. (124 aa)
LCP2Lymphocyte cytosolic protein 2. (570 aa)
ENSCPOP00000026228Ig-like domain-containing protein. (134 aa)
ENSCPOP00000026512Ig-like domain-containing protein. (140 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (705 aa)
ENSCPOP00000027005UBIQUITIN_CONJUGAT_2 domain-containing protein. (83 aa)
ENSCPOP00000027155Ig-like domain-containing protein. (117 aa)
ENSCPOP00000027199Ig-like domain-containing protein. (128 aa)
FCER1GHigh affinity immunoglobulin epsilon receptor subunit gamma; Adapter protein containing an immunoreceptor tyrosine-based activation motif (ITAM) that transduces activation signals from various immunoreceptors. As a component of the high-affinity immunoglobulin E (IgE) receptor, mediates allergic inflammatory signaling in mast cells. As a constitutive component of interleukin-3 receptor complex, selectively mediates interleukin 4/IL4 production by basophils priming T-cells toward effector T-helper 2 subset. Associates with pattern recognition receptors CLEC4D and CLEC4E to form a functi [...] (86 aa)
ENSCPOP00000028125Ig-like domain-containing protein. (117 aa)
ENSCPOP00000028279Ig-like domain-containing protein. (134 aa)
ENSCPOP00000028369Ig-like domain-containing protein. (135 aa)
GRAP2GRB2 related adaptor protein 2. (327 aa)
ENSCPOP00000028898Ig-like domain-containing protein. (133 aa)
ENSCPOP00000028990Ig-like domain-containing protein. (138 aa)
ENSCPOP00000029145Ig-like domain-containing protein. (136 aa)
ENSCPOP00000029309Ig-like domain-containing protein. (124 aa)
ENSCPOP00000029468Ig-like domain-containing protein. (122 aa)
SPNS1Sphingolipid transporter 1 (putative). (528 aa)
MAPK10Mitogen-activated protein kinase 10. (434 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
SPNS3Sphingolipid transporter 3 (putative). (512 aa)
TECTyrosine-protein kinase. (631 aa)
ENSCPOP00000032616Ig-like domain-containing protein. (125 aa)
ENSCPOP00000032517Ig-like domain-containing protein. (129 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (749 aa)
PPP3R1Uncharacterized protein. (169 aa)
UbcUncharacterized protein. (159 aa)
ENSCPOP00000031920Ig-like domain-containing protein. (117 aa)
CSDE1Cold shock domain-containing protein E1; RNA-binding protein. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain (By similarity). (779 aa)
ENSCPOP00000031763Ig-like domain-containing protein. (134 aa)
ENSCPOP00000031748Ig-like domain-containing protein. (136 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
LOC106026776Uncharacterized protein. (227 aa)
BCL10BCL10 immune signaling adaptor. (234 aa)
ENSCPOP00000031333Ig-like domain-containing protein. (114 aa)
ENSCPOP00000031332Ig-like domain-containing protein. (138 aa)
BTKTyrosine-protein kinase. (659 aa)
ENSCPOP00000031130Ig-like domain-containing protein. (136 aa)
ENSCPOP00000030838UBIQUITIN_CONJUGAT_2 domain-containing protein. (133 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (711 aa)
ENSCPOP00000030758Ig-like domain-containing protein. (122 aa)
ENSCPOP00000030754Ig-like domain-containing protein. (139 aa)
ENSCPOP00000030342Ig-like domain-containing protein. (124 aa)
ENSCPOP00000030140Ig-like domain-containing protein. (164 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
ENSCPOP00000029769Ig-like domain-containing protein. (139 aa)
ENSCPOP00000029705Ig-like domain-containing protein. (124 aa)
LOC100723205Death domain-containing protein. (231 aa)
ENSCPOP00000029546UBIQUITIN_CONJUGAT_2 domain-containing protein. (140 aa)
SYKTyrosine-protein kinase. (579 aa)
ITKTyrosine-protein kinase. (626 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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