STRINGSTRING
INCENP INCENP ANAPC16 ANAPC16 CENPL CENPL DYNLL2 DYNLL2 PSMD4 PSMD4 PSMD14 PSMD14 CDC26 CDC26 STAG2 STAG2 AURKB AURKB Mapre1 Mapre1 PMF1 PMF1 CENPS CENPS DYNLL1 DYNLL1 PPP2R5E PPP2R5E PSMD2 PSMD2 TUBB4A TUBB4A CDC20B CDC20B ENSCPOP00000024706 ENSCPOP00000024706 PPP2R1B PPP2R1B PSMC3 PSMC3 PPP2CA PPP2CA CENPU CENPU Mtus2 Mtus2 BUB3 BUB3 PPP2R5A PPP2R5A BIRC5 BIRC5 PSME1 PSME1 PDS5B PDS5B ENSCPOP00000023065 ENSCPOP00000023065 ANAPC10 ANAPC10 WAPL WAPL XPO1 XPO1 PSMA3 PSMA3 FAM89A FAM89A ENSCPOP00000022293 ENSCPOP00000022293 PAFAH1B1 PAFAH1B1 CKAP5 CKAP5 Ercc6l2 Ercc6l2 ENSCPOP00000021762 ENSCPOP00000021762 PSMD1 PSMD1 UBE2C UBE2C ZWINT ZWINT UBE2D1 UBE2D1 H0WDT2_CAVPO H0WDT2_CAVPO PSMB10 PSMB10 H0WAD6_CAVPO H0WAD6_CAVPO PSMD5 PSMD5 KIF2B KIF2B PSMB11 PSMB11 PSMB3 PSMB3 SGO1 SGO1 Cenpe Cenpe PSMA4 PSMA4 NDE1 NDE1 B9D2 B9D2 Psmd9 Psmd9 LOC100716197 LOC100716197 H0W160_CAVPO H0W160_CAVPO CLIP2 CLIP2 LOC100716847 LOC100716847 PPP2R5B PPP2R5B H0VZC1_CAVPO H0VZC1_CAVPO LOC100732987 LOC100732987 LOC100731885 LOC100731885 MEIOC MEIOC H0VWS1_CAVPO H0VWS1_CAVPO PSMC2 PSMC2 KIF18A KIF18A Rps27 Rps27 ANAPC7 ANAPC7 SEC13 SEC13 PSMA1 PSMA1 PSMB4 PSMB4 PSMD3 PSMD3 Psmd10 Psmd10 NUF2 NUF2 TM7SF3 TM7SF3 DYNC1I2 DYNC1I2 CENPF CENPF PSMA7 PSMA7 PSMB5 PSMB5 PSMF1 PSMF1 Anapc11 Anapc11 PSMA5 PSMA5 SKA1 SKA1 RAD21 RAD21 CENPM CENPM BUB1 BUB1 ANAPC4 ANAPC4 TUBA1B TUBA1B NDEL1 NDEL1 UBE2S UBE2S AURKC AURKC TUBB2B TUBB2B PSMA8 PSMA8 TAOK1 TAOK1 CLIP1 CLIP1 DYNC1LI2 DYNC1LI2 TUBB6 TUBB6 PSME3 PSME3 Psma2 Psma2 KIF2A KIF2A MAPRE2 MAPRE2 KNL1 KNL1 Ubc Ubc PSME2 PSME2 MAD2L1 MAD2L1 ENSCPOP00000031834 ENSCPOP00000031834 ENSCPOP00000031632 ENSCPOP00000031632 ENSCPOP00000031620 ENSCPOP00000031620 PSMC1 PSMC1 ANAPC15 ANAPC15 CDC27 CDC27 Pttg1 Pttg1 KIF2C KIF2C PLK1 PLK1 TUBB1 TUBB1 ENSCPOP00000030117 ENSCPOP00000030117 UBB UBB Clasp2 Clasp2 FAM89B FAM89B CLASP1 CLASP1 ITGB3BP ITGB3BP CENPH CENPH LOC100729187 LOC100729187 STAG1 STAG1 SKA2 SKA2 PSMA6 PSMA6 PSMB2 PSMB2 PSMD12 PSMD12 TUBB4B TUBB4B NUP37 NUP37 PSME4 PSME4 DYNC1LI1 DYNC1LI1 PDS5A PDS5A ANAPC5 ANAPC5 DSN1 DSN1 PPP2R5C PPP2R5C UBA52 UBA52 RANBP2 RANBP2 RAD21L1 RAD21L1 PSMB8 PSMB8 CENPP CENPP CENPT CENPT ESPL1 ESPL1 Nup85 Nup85 PSMB1 PSMB1 CDCA8 CDCA8 ZWILCH ZWILCH KNTC1 KNTC1 PSMB6 PSMB6 TCERG1L TCERG1L CENPC CENPC PSMB9 PSMB9 UBE2E1 UBE2E1 RCC2 RCC2 NSL1 NSL1 MAD1L1 MAD1L1 Sgo2 Sgo2 TUBA8 TUBA8 PSMD13 PSMD13 PSMC4 PSMC4 CENPN CENPN DYNC1H1 DYNC1H1 RANGAP1 RANGAP1 TUBA4A TUBA4A TUBE1 TUBE1 ZW10 ZW10 MAPRE3 MAPRE3 PPP2CB PPP2CB NUP160 NUP160 CDC16 CDC16 CENPO CENPO Hdac8 Hdac8 PPP1CC PPP1CC Rps27a Rps27a NDC80 NDC80 LOC100731490 LOC100731490 SPC25 SPC25 CDC20 CDC20 PSMD6 PSMD6 NUP98 NUP98 CDCA5 CDCA5 CENPK CENPK PSMB7 PSMB7 CENPQ CENPQ LOC100734047 LOC100734047 NUP107 NUP107 SMC3 SMC3 Bub1b Bub1b AHCTF1 AHCTF1 H0VEL3_CAVPO H0VEL3_CAVPO PSMC6 PSMC6 ERCC6L ERCC6L PSMC5 PSMC5 PSMD7 PSMD7 H0VIB7_CAVPO H0VIB7_CAVPO PSMD8 PSMD8 PPP2R5D PPP2R5D SPDL1 SPDL1 Nup43 Nup43 CDC23 CDC23 NUDC NUDC NUP133 NUP133 PSMD11 PSMD11 ANAPC2 ANAPC2 SMC1A SMC1A ANAPC1 ANAPC1 CENPA CENPA SEH1L SEH1L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
INCENPInner centromere protein. (874 aa)
ANAPC16Anaphase promoting complex subunit 16. (118 aa)
CENPLCentromere protein L. (346 aa)
DYNLL2Dynein light chain. (89 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (377 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
CDC26Cell division cycle 26. (85 aa)
STAG2Stromal antigen 2. (1149 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (339 aa)
Mapre1Uncharacterized protein. (268 aa)
PMF1Polyamine modulated factor 1. (203 aa)
CENPSCentromere protein S. (135 aa)
DYNLL1Dynein light chain. (89 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa)
CDC20BCell division cycle 20B. (525 aa)
ENSCPOP00000024706WD_REPEATS_REGION domain-containing protein. (357 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (696 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
CENPUCentromere protein U. (405 aa)
Mtus2Uncharacterized protein. (348 aa)
BUB3BUB3 mitotic checkpoint protein. (326 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (487 aa)
BIRC5Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules (By simi [...] (142 aa)
PSME1Proteasome activator subunit 1. (249 aa)
PDS5BPDS5 cohesin associated factor B. (1396 aa)
ENSCPOP00000023065ANK_REP_REGION domain-containing protein. (179 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
WAPLWAPL cohesin release factor. (1210 aa)
XPO1Exportin 1. (1062 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
FAM89AFamily with sequence similarity 89 member A. (174 aa)
ENSCPOP00000022293Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (459 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
CKAP5Cytoskeleton associated protein 5. (2032 aa)
Ercc6l2Uncharacterized protein. (1539 aa)
ENSCPOP00000021762Uncharacterized protein. (105 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
UBE2CUbiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
ZWINTZW10 interacting kinetochore protein. (276 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (139 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
PSMB10Proteasome subunit beta. (273 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
KIF2BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (606 aa)
PSMB11Proteasome subunit beta. (297 aa)
PSMB3Proteasome subunit beta. (207 aa)
SGO1Shugoshin 1. (522 aa)
CenpeKinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2439 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
NDE1NudE neurodevelopment protein 1. (350 aa)
B9D2B9 domain containing 2. (175 aa)
Psmd9PDZ domain-containing protein. (223 aa)
LOC100716197Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
H0W160_CAVPOUncharacterized protein. (589 aa)
CLIP2CAP-Gly domain containing linker protein 2. (1021 aa)
LOC100716847Uncharacterized protein. (80 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
H0VZC1_CAVPOUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (199 aa)
LOC100732987Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
LOC100731885Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
MEIOCMeiosis specific with coiled-coil domain. (919 aa)
H0VWS1_CAVPOANK_REP_REGION domain-containing protein. (213 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (458 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (896 aa)
Rps2740S ribosomal protein S27. (84 aa)
ANAPC7Anaphase promoting complex subunit 7. (555 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (322 aa)
PSMA1Proteasome subunit alpha type. (270 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (263 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
Psmd10ANK_REP_REGION domain-containing protein. (232 aa)
NUF2NUF2 component of NDC80 kinetochore complex. (470 aa)
TM7SF3Transmembrane 7 superfamily member 3. (570 aa)
DYNC1I2Dynein cytoplasmic 1 intermediate chain 2. (638 aa)
CENPFCentromere protein F. (3022 aa)
PSMA7Proteasome endopeptidase complex. (248 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
Anapc11RING-type domain-containing protein. (84 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
SKA1Spindle and kinetochore associated complex subunit 1. (254 aa)
RAD21RAD21 cohesin complex component. (631 aa)
CENPMCentromere protein M. (180 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1031 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (345 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (214 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (257 aa)
TUBB2BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
TAOK1TAO kinase 1. (963 aa)
CLIP1CAP-Gly domain containing linker protein 1. (1437 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (492 aa)
TUBB6Tubulin beta 6 class V; Belongs to the tubulin family. (318 aa)
PSME3Proteasome activator subunit 3. (254 aa)
Psma2Proteasome subunit alpha type. (234 aa)
KIF2AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (663 aa)
MAPRE2Microtubule associated protein RP/EB family member 2. (326 aa)
KNL1Kinetochore scaffold 1. (2185 aa)
UbcUncharacterized protein. (159 aa)
PSME2Proteasome activator subunit 2. (239 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
ENSCPOP00000031834Uncharacterized protein. (73 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
ENSCPOP00000031620Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (297 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
ANAPC15Anaphase promoting complex subunit 15. (134 aa)
CDC27Cell division cycle 27. (825 aa)
Pttg1Uncharacterized protein. (198 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (725 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
ENSCPOP00000030117Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (188 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
Clasp2Uncharacterized protein. (1497 aa)
FAM89BFamily with sequence similarity 89 member B. (189 aa)
CLASP1Cytoplasmic linker associated protein 1. (1524 aa)
ITGB3BPIntegrin subunit beta 3 binding protein. (198 aa)
CENPHCentromere protein H. (277 aa)
LOC100729187Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
STAG1Stromal antigen 1. (1265 aa)
SKA2Spindle and kinetochore associated complex subunit 2. (121 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
NUP37Nucleoporin 37. (326 aa)
PSME4Proteasome activator subunit 4. (1827 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (524 aa)
PDS5APDS5 cohesin associated factor A. (1337 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
DSN1DSN1 component of MIS12 kinetochore complex. (354 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (589 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
RANBP2RAN binding protein 2. (3026 aa)
RAD21L1RAD21 cohesin complex component like 1. (554 aa)
PSMB8Proteasome subunit beta. (273 aa)
CENPPCentromere protein P. (283 aa)
CENPTCentromere protein T. (497 aa)
ESPL1Extra spindle pole bodies like 1, separase. (2115 aa)
Nup85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (655 aa)
PSMB1Proteasome subunit beta. (241 aa)
CDCA8Cell division cycle associated 8. (277 aa)
ZWILCHZwilch kinetochore protein. (586 aa)
KNTC1Kinetochore associated 1. (2158 aa)
PSMB6Proteasome subunit beta. (239 aa)
TCERG1LTranscription elongation regulator 1 like. (579 aa)
CENPCCentromere protein C. (942 aa)
PSMB9Proteasome subunit beta. (219 aa)
UBE2E1Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
RCC2Regulator of chromosome condensation 2. (427 aa)
NSL1NSL1 component of MIS12 kinetochore complex. (326 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (717 aa)
Sgo2Uncharacterized protein. (1182 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (315 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
CENPNCentromere protein N. (345 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4637 aa)
RANGAP1Ran GTPase activating protein 1. (585 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
TUBE1Tubulin epsilon 1; Belongs to the tubulin family. (478 aa)
ZW10Zw10 kinetochore protein. (778 aa)
MAPRE3Microtubule associated protein RP/EB family member 3. (281 aa)
PPP2CBSerine/threonine-protein phosphatase. (308 aa)
NUP160Nucleoporin 160. (1402 aa)
CDC16Cell division cycle 16. (620 aa)
CENPOCentromere protein O. (297 aa)
Hdac8Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (415 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
NDC80NDC80 kinetochore complex component. (644 aa)
LOC100731490Uncharacterized protein. (740 aa)
SPC25SPC25 component of NDC80 kinetochore complex. (226 aa)
CDC20Cell division cycle 20. (499 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
NUP98Nucleoporin 98. (1784 aa)
CDCA5Cell division cycle associated 5. (248 aa)
CENPKCentromere protein K. (268 aa)
PSMB7Proteasome subunit beta. (277 aa)
CENPQCentromere protein Q. (264 aa)
LOC100734047Uncharacterized protein. (567 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (897 aa)
SMC3Structural maintenance of chromosomes protein. (1217 aa)
Bub1bUncharacterized protein. (1043 aa)
AHCTF1AT-hook containing transcription factor 1. (2168 aa)
H0VEL3_CAVPOEB1 C-terminal domain-containing protein. (254 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
ERCC6LERCC excision repair 6 like, spindle assembly checkpoint helicase. (1238 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
H0VIB7_CAVPOUncharacterized protein. (439 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (594 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (606 aa)
Nup43WD_REPEATS_REGION domain-containing protein. (378 aa)
CDC23Cell division cycle 23. (597 aa)
NUDCNuclear distribution C, dynein complex regulator. (332 aa)
NUP133Nucleoporin 133. (1154 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (827 aa)
SMC1AStructural maintenance of chromosomes protein. (1222 aa)
ANAPC1Anaphase promoting complex subunit 1. (1941 aa)
CENPACentromere protein A. (131 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (418 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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