19 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TBK1	TANK binding kinase 1. (729 aa)
	Rps27a	Ubiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
	DTX4	Deltex E3 ubiquitin ligase 4. (620 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
	TRIM56	Tripartite motif containing 56. (732 aa)
	TRIM32	Tripartite motif containing 32. (653 aa)
	DDX41	DEAD-box helicase 41. (622 aa)
	UBB	Polyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
	STING1	Transmembrane protein 173. (379 aa)
	ENSCPOP00000031632	Ubiquitin-like domain-containing protein. (141 aa)
	Ubc	Uncharacterized protein. (159 aa)
	IRF3	Interferon regulatory factor 3. (389 aa)
	H0WAD6_CAVPO	Ubiquitin-like domain-containing protein. (111 aa)
	H0WDT2_CAVPO	Ubiquitin-like domain-containing protein. (127 aa)
	TREX2	Three prime repair exonuclease 2. (236 aa)
	TREX1	Three prime repair exonuclease 1. (314 aa)
	Trim58	Uncharacterized protein. (472 aa)
	TRIM21	Tripartite motif containing 21. (467 aa)
	ZBP1	Z-DNA binding protein 1. (402 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX41	IRF3	ENSCPOP00000028918	ENSCPOP00000015462	DEAD-box helicase 41.	Interferon regulatory factor 3.	0.626
DDX41	STING1	ENSCPOP00000028918	ENSCPOP00000030449	DEAD-box helicase 41.	Transmembrane protein 173.	0.632
DDX41	TBK1	ENSCPOP00000028918	ENSCPOP00000009741	DEAD-box helicase 41.	TANK binding kinase 1.	0.697
DDX41	TRIM21	ENSCPOP00000028918	ENSCPOP00000010962	DEAD-box helicase 41.	Tripartite motif containing 21.	0.799
DDX41	TRIM32	ENSCPOP00000028918	ENSCPOP00000028854	DEAD-box helicase 41.	Tripartite motif containing 32.	0.446
DDX41	TRIM56	ENSCPOP00000028918	ENSCPOP00000023114	DEAD-box helicase 41.	Tripartite motif containing 56.	0.609
DDX41	Trim58	ENSCPOP00000028918	ENSCPOP00000012888	DEAD-box helicase 41.	Uncharacterized protein.	0.775
DDX41	UBB	ENSCPOP00000028918	ENSCPOP00000029946	DEAD-box helicase 41.	Polyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...]	0.578
DDX41	Ubc	ENSCPOP00000028918	ENSCPOP00000031925	DEAD-box helicase 41.	Uncharacterized protein.	0.577
DDX41	ZBP1	ENSCPOP00000028918	ENSCPOP00000007699	DEAD-box helicase 41.	Z-DNA binding protein 1.	0.436
DTX4	ENSCPOP00000031632	ENSCPOP00000001484	ENSCPOP00000031632	Deltex E3 ubiquitin ligase 4.	Ubiquitin-like domain-containing protein.	0.677
DTX4	H0WAD6_CAVPO	ENSCPOP00000001484	ENSCPOP00000019948	Deltex E3 ubiquitin ligase 4.	Ubiquitin-like domain-containing protein.	0.677
DTX4	H0WDT2_CAVPO	ENSCPOP00000001484	ENSCPOP00000021155	Deltex E3 ubiquitin ligase 4.	Ubiquitin-like domain-containing protein.	0.597
DTX4	IRF3	ENSCPOP00000001484	ENSCPOP00000015462	Deltex E3 ubiquitin ligase 4.	Interferon regulatory factor 3.	0.491
DTX4	Rps27a	ENSCPOP00000001484	ENSCPOP00000005248	Deltex E3 ubiquitin ligase 4.	Ubiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...]	0.677
DTX4	STING1	ENSCPOP00000001484	ENSCPOP00000030449	Deltex E3 ubiquitin ligase 4.	Transmembrane protein 173.	0.489
DTX4	TBK1	ENSCPOP00000001484	ENSCPOP00000009741	Deltex E3 ubiquitin ligase 4.	TANK binding kinase 1.	0.439
DTX4	UBA52	ENSCPOP00000001484	ENSCPOP00000000308	Deltex E3 ubiquitin ligase 4.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.597
DTX4	UBB	ENSCPOP00000001484	ENSCPOP00000029946	Deltex E3 ubiquitin ligase 4.	Polyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...]	0.674
DTX4	Ubc	ENSCPOP00000001484	ENSCPOP00000031925	Deltex E3 ubiquitin ligase 4.	Uncharacterized protein.	0.674