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CAPZA1 CAPZA1 FKBP4 FKBP4 Hsp90aa1 Hsp90aa1 DNAJA4 DNAJA4 Dnaja1 Dnaja1 DNAJB13 DNAJB13 DCTN6 DCTN6 H0VIB7_CAVPO H0VIB7_CAVPO DYNC1LI1 DYNC1LI1 TUBB4B TUBB4B TUBB2B TUBB2B Dctn1 Dctn1 DCTN2 DCTN2 TUBA1B TUBA1B CAPZB CAPZB DNAJB5 DNAJB5 DYNC1I2 DYNC1I2 ACTR1A ACTR1A NR3C1 NR3C1 QRSL1 QRSL1 DCTN4 DCTN4 AR AR LOC100731885 LOC100731885 LOC100732987 LOC100732987 TMEM59L TMEM59L LOC100716197 LOC100716197 CAPZA3 CAPZA3 LOC100717205 LOC100717205 ENSCPOP00000021762 ENSCPOP00000021762 FKBP5 FKBP5 ENSCPOP00000022293 ENSCPOP00000022293 LOC100725824 LOC100725824 STIP1 STIP1 Pgr Pgr ENSCPOP00000024193 ENSCPOP00000024193 TUBB4A TUBB4A DYNLL1 DYNLL1 DCTN5 DCTN5 HSPA2 HSPA2 DCTN3 DCTN3 TTC28 TTC28 DNAJB1 DNAJB1 DYNLL2 DYNLL2 PTGES3 PTGES3 LOC100729187 LOC100729187 ENSCPOP00000030021 ENSCPOP00000030021 TUBB1 TUBB1 ENSCPOP00000031515 ENSCPOP00000031515 ENSCPOP00000031620 ENSCPOP00000031620 HSPA1L HSPA1L NR3C2 NR3C2 TUBB6 TUBB6 DYNC1LI2 DYNC1LI2 TUBA8 TUBA8 ENSCPOP00000032931 ENSCPOP00000032931 DNAJB4 DNAJB4 ACTR10 ACTR10 CAPZA2 CAPZA2 Dnaja2 Dnaja2 TUBE1 TUBE1 TTC12 TTC12 TUBA4A TUBA4A ZC3H7A ZC3H7A HSPA8 HSPA8 DYNC1H1 DYNC1H1 FAM193A FAM193A HSP90AB1 HSP90AB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CAPZA1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
FKBP4Peptidylprolyl isomerase. (458 aa)
Hsp90aa1Heat shock protein 90 alpha family class A member 1. (733 aa)
DNAJA4DnaJ heat shock protein family (Hsp40) member A4. (397 aa)
Dnaja1Uncharacterized protein. (397 aa)
DNAJB13DnaJ heat shock protein family (Hsp40) member B13. (316 aa)
DCTN6Dynactin subunit 6. (190 aa)
H0VIB7_CAVPOUncharacterized protein. (439 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (524 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
TUBB2BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
Dctn1CAP-Gly domain-containing protein. (1281 aa)
DCTN2Dynactin subunit 2. (402 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (301 aa)
DNAJB5DnaJ heat shock protein family (Hsp40) member B5. (382 aa)
DYNC1I2Dynein cytoplasmic 1 intermediate chain 2. (638 aa)
ACTR1AActin related protein 1A. (376 aa)
NR3C1Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP [...] (772 aa)
QRSL1Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily. (530 aa)
DCTN4Dynactin subunit 4. (467 aa)
ARAndrogen receptor. (926 aa)
LOC100731885Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
LOC100732987Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
TMEM59LTransmembrane protein 59 like. (344 aa)
LOC100716197Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
CAPZA3F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (263 aa)
LOC100717205Uncharacterized protein; Belongs to the heat shock protein 70 family. (641 aa)
ENSCPOP00000021762Uncharacterized protein. (105 aa)
FKBP5Peptidylprolyl isomerase. (456 aa)
ENSCPOP00000022293Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (459 aa)
LOC100725824HATPase_c domain-containing protein. (695 aa)
STIP1Stress induced phosphoprotein 1. (543 aa)
PgrUncharacterized protein. (428 aa)
ENSCPOP00000024193Uncharacterized protein. (355 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa)
DYNLL1Dynein light chain. (89 aa)
DCTN5Dynactin subunit 5. (182 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (620 aa)
DCTN3Dynactin subunit 3. (186 aa)
TTC28Tetratricopeptide repeat domain 28. (2214 aa)
DNAJB1DnaJ heat shock protein family (Hsp40) member B1. (339 aa)
DYNLL2Dynein light chain. (89 aa)
PTGES3Prostaglandin E synthase 3. (160 aa)
LOC100729187Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
ENSCPOP00000030021Uncharacterized protein; Belongs to the heat shock protein 70 family. (537 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
ENSCPOP00000031515Uncharacterized protein. (406 aa)
ENSCPOP00000031620Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (297 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (642 aa)
NR3C2Nuclear receptor subfamily 3 group C member 2. (1010 aa)
TUBB6Tubulin beta 6 class V; Belongs to the tubulin family. (318 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (492 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
ENSCPOP00000032931CR-type domain-containing protein. (379 aa)
DNAJB4DnaJ heat shock protein family (Hsp40) member B4. (337 aa)
ACTR10Actin related protein 10; Belongs to the actin family. (416 aa)
CAPZA2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (279 aa)
Dnaja2Uncharacterized protein. (412 aa)
TUBE1Tubulin epsilon 1; Belongs to the tubulin family. (478 aa)
TTC12Tetratricopeptide repeat domain 12. (705 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
ZC3H7AZinc finger CCCH-type containing 7A. (973 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (646 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4637 aa)
FAM193AFamily with sequence similarity 193 member A. (1422 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (723 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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