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COL3A1 COL3A1 HRAS HRAS CSDE1 CSDE1 GRB2 GRB2 COL6A3 COL6A3 ENSCPOP00000029356 ENSCPOP00000029356 ENSCPOP00000029275 ENSCPOP00000029275 SPTBN1 SPTBN1 GFRA4 GFRA4 PTPRE PTPRE COL9A1 COL9A1 ST8SIA4 ST8SIA4 PTPRA PTPRA FYN FYN MAPK3 MAPK3 ENSCPOP00000024053 ENSCPOP00000024053 ST8SIA2 ST8SIA2 CREB1 CREB1 CACNA1S CACNA1S CACNA1G CACNA1G SPTA1 SPTA1 COL5A1 COL5A1 SPTB SPTB COL4A1 COL4A1 RPS6KA5 RPS6KA5 SPTBN2 SPTBN2 MAPK1 MAPK1 CACNA1H CACNA1H CACNA1I CACNA1I CNTN2 CNTN2 KRAS KRAS NRAS NRAS COL4A2 COL4A2 SPTAN1 SPTAN1 SPTBN4 SPTBN4 COL5A2 COL5A2 NCAM1 NCAM1 SOS1 SOS1 NCAM2 NCAM2 PTK2 PTK2 COL2A1 COL2A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
COL3A1Collagen type III alpha 1 chain. (1462 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
CSDE1Cold shock domain-containing protein E1; RNA-binding protein. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain (By similarity). (779 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
COL6A3Collagen type VI alpha 3 chain. (2507 aa)
ENSCPOP00000029356Uncharacterized protein. (1121 aa)
ENSCPOP00000029275VWFA domain-containing protein. (72 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2364 aa)
GFRA4GDNF family receptor alpha 4. (280 aa)
PTPREReceptor-type tyrosine-protein phosphatase. (723 aa)
COL9A1Collagen type IX alpha 1 chain. (921 aa)
ST8SIA4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (359 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (799 aa)
FYNTyrosine-protein kinase. (537 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
ENSCPOP00000024053Uncharacterized protein. (948 aa)
ST8SIA2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (375 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1867 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2372 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2415 aa)
COL5A1Collagen type V alpha 1 chain. (1822 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2358 aa)
COL4A1Collagen type IV alpha 1 chain. (1658 aa)
RPS6KA5Ribosomal protein S6 kinase. (835 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2386 aa)
MAPK1Mitogen-activated protein kinase. (325 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2337 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2067 aa)
CNTN2Contactin 2. (1041 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
NRASGTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa)
COL4A2Collagen type IV alpha 2 chain. (1479 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2418 aa)
SPTBN4Spectrin beta chain; Belongs to the spectrin family. (2530 aa)
COL5A2Collagen type V alpha 2 chain. (1499 aa)
NCAM1Neural cell adhesion molecule 1. (848 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1276 aa)
NCAM2Neural cell adhesion molecule 2. (828 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1084 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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