STRINGSTRING
PSMB2 PSMB2 Psma2 Psma2 PSME3 PSME3 SEL1L SEL1L VCP VCP PEX3 PEX3 PSMC1 PSMC1 ABCA3 ABCA3 ENSCPOP00000031632 ENSCPOP00000031632 PSME2 PSME2 Ubc Ubc PSMD12 PSMD12 PSMD4 PSMD4 PSMD14 PSMD14 DERL1 DERL1 EIF2S1 EIF2S1 RNF185 RNF185 PSMD2 PSMD2 PSMC3 PSMC3 ERLIN2 ERLIN2 APOA1 APOA1 ATP5IF1 ATP5IF1 ABCC9 ABCC9 LRP2BP LRP2BP DERL2 DERL2 UBB UBB ABCA6 ABCA6 PSMA6 PSMA6 PSMC5 PSMC5 ABCD1 ABCD1 PSME4 PSME4 ABCA9 ABCA9 PSMA8 PSMA8 Abcb1 Abcb1 ABCF3 ABCF3 CFTR CFTR ABCC3 ABCC3 PSMA5 PSMA5 PSMF1 PSMF1 SEL1L2 SEL1L2 PSMB5 PSMB5 SMPDL3A SMPDL3A PSMA7 PSMA7 ABCA2 ABCA2 DERL3 DERL3 Psmd10 Psmd10 ABCC4 ABCC4 PSMD3 PSMD3 PTCHD1 PTCHD1 ABCG1 ABCG1 PSMB4 PSMB4 PSMA1 PSMA1 ABCA4 ABCA4 PSMC2 PSMC2 H0VWS1_CAVPO H0VWS1_CAVPO ERLIN1 ERLIN1 Psmd9 Psmd9 PTCHD4 PTCHD4 PSMA4 PSMA4 H0W664_CAVPO H0W664_CAVPO ABCB9 ABCB9 PSMB3 PSMB3 ERLEC1 ERLEC1 PSMB11 PSMB11 ABCG5 ABCG5 PSMD5 PSMD5 KCNJ11 KCNJ11 H0WAD6_CAVPO H0WAD6_CAVPO ABCG8 ABCG8 UBA52 UBA52 Eif2s3 Eif2s3 PSMB8 PSMB8 SEL1L3 SEL1L3 PSMB1 PSMB1 PSMB6 PSMB6 ABCD3 ABCD3 PSMB9 PSMB9 OS9 OS9 ABCB5 ABCB5 PSMD13 PSMD13 ABCC5 ABCC5 PSMD7 PSMD7 PSMD8 PSMD8 ABCC2 ABCC2 ABCB7 ABCB7 ABCD2 ABCD2 ABCA7 ABCA7 PSMC4 PSMC4 ABCB8 ABCB8 ABCB6 ABCB6 ABCC1 ABCC1 ABCC6 ABCC6 SPATA5 SPATA5 DELE1 DELE1 Rps27a Rps27a ABCA12 ABCA12 PSMD6 PSMD6 ABCG4 ABCG4 ABCC12 ABCC12 PSMB7 PSMB7 SPATA5L1 SPATA5L1 PSMC6 PSMC6 PSMD11 PSMD11 ABCC10 ABCC10 ABCF1 ABCF1 PTCHD3 PTCHD3 PSMB10 PSMB10 H0WDT2_CAVPO H0WDT2_CAVPO ENSCPOP00000021511 ENSCPOP00000021511 PSMD1 PSMD1 LOC100732684 LOC100732684 PEX19 PEX19 RNF5 RNF5 PSMA3 PSMA3 PLEKHD1 PLEKHD1 EIF2S2 EIF2S2 ABCA5 ABCA5 ENSCPOP00000023065 ENSCPOP00000023065 ENSCPOP00000023107 ENSCPOP00000023107 PSME1 PSME1 ABCB10 ABCB10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMB2Proteasome subunit beta. (201 aa)
Psma2Proteasome subunit alpha type. (234 aa)
PSME3Proteasome activator subunit 3. (254 aa)
SEL1LSEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (798 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
PEX3Peroxisomal biogenesis factor 3. (373 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
ABCA3ATP binding cassette subfamily A member 3. (1704 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
PSME2Proteasome activator subunit 2. (239 aa)
UbcUncharacterized protein. (159 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (377 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
RNF185Ring finger protein 185. (192 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
ERLIN2ER lipid raft associated 2. (339 aa)
APOA1Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (264 aa)
ATP5IF1ATP synthase inhibitory factor subunit 1. (103 aa)
ABCC9ATP binding cassette subfamily C member 9. (1546 aa)
LRP2BPLRP2 binding protein. (348 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
ABCA6ATP binding cassette subfamily A member 6. (1465 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
ABCD1ATP binding cassette subfamily D member 1. (723 aa)
PSME4Proteasome activator subunit 4. (1827 aa)
ABCA9ATP binding cassette subfamily A member 9. (1579 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
Abcb1Uncharacterized protein. (1243 aa)
ABCF3ATP binding cassette subfamily F member 3. (722 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1448 aa)
ABCC3ATP binding cassette subfamily C member 3. (1523 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
SEL1L2SEL1L2 adaptor subunit of ERAD E3 ligase. (685 aa)
PSMB5Proteasome subunit beta. (263 aa)
SMPDL3ASphingomyelin phosphodiesterase acid like 3A. (410 aa)
PSMA7Proteasome endopeptidase complex. (248 aa)
ABCA2ATP binding cassette subfamily A member 2. (2427 aa)
DERL3Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (234 aa)
Psmd10ANK_REP_REGION domain-containing protein. (232 aa)
ABCC4ATP binding cassette subfamily C member 4. (1324 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
PTCHD1Patched domain containing 1. (888 aa)
ABCG1ATP binding cassette subfamily G member 1. (666 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (263 aa)
PSMA1Proteasome subunit alpha type. (270 aa)
ABCA4ATP binding cassette subfamily A member 4. (2270 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (458 aa)
H0VWS1_CAVPOANK_REP_REGION domain-containing protein. (213 aa)
ERLIN1ER lipid raft associated 1. (348 aa)
Psmd9PDZ domain-containing protein. (223 aa)
PTCHD4Patched domain containing 4. (895 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
H0W664_CAVPOUncharacterized protein. (1232 aa)
ABCB9ATP binding cassette subfamily B member 9. (766 aa)
PSMB3Proteasome subunit beta. (207 aa)
ERLEC1Endoplasmic reticulum lectin 1. (457 aa)
PSMB11Proteasome subunit beta. (297 aa)
ABCG5ATP binding cassette subfamily G member 5. (480 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
KCNJ11ATP-sensitive inward rectifier potassium channel 11; This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Can form cardiac and smo [...] (390 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
ABCG8ATP binding cassette subfamily G member 8. (658 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
Eif2s3Tr-type G domain-containing protein. (472 aa)
PSMB8Proteasome subunit beta. (273 aa)
SEL1L3SEL1L family member 3. (1078 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMB6Proteasome subunit beta. (239 aa)
ABCD3ATP binding cassette subfamily D member 3. (611 aa)
PSMB9Proteasome subunit beta. (219 aa)
OS9OS9 endoplasmic reticulum lectin. (665 aa)
ABCB5ATP binding cassette subfamily B member 5. (1202 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (315 aa)
ABCC5ATP binding cassette subfamily C member 5. (1437 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
ABCC2ATP binding cassette subfamily C member 2. (1537 aa)
ABCB7ATP binding cassette subfamily B member 7. (752 aa)
ABCD2ATP binding cassette subfamily D member 2. (740 aa)
ABCA7ATP binding cassette subfamily A member 7. (2108 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
ABCB8ATP binding cassette subfamily B member 8. (720 aa)
ABCB6ATP binding cassette subfamily B member 6 (Langereis blood group). (843 aa)
ABCC1ATP binding cassette subfamily C member 1. (1531 aa)
ABCC6ATP binding cassette subfamily C member 6. (1436 aa)
SPATA5Spermatogenesis associated 5. (884 aa)
DELE1DAP3 binding cell death enhancer 1. (513 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
ABCA12ATP binding cassette subfamily A member 12. (2597 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
ABCG4ATP binding cassette subfamily G member 4. (646 aa)
ABCC12ATP binding cassette subfamily C member 12. (1365 aa)
PSMB7Proteasome subunit beta. (277 aa)
SPATA5L1Spermatogenesis associated 5 like 1; Belongs to the AAA ATPase family. (634 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
ABCC10ATP binding cassette subfamily C member 10. (1486 aa)
ABCF1ATP binding cassette subfamily F member 1. (775 aa)
PTCHD3Patched domain containing 3. (813 aa)
PSMB10Proteasome subunit beta. (273 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
ENSCPOP00000021511Uncharacterized protein. (72 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
LOC100732684Uncharacterized protein. (1219 aa)
PEX19Uncharacterized protein. (299 aa)
RNF5Ring finger protein 5. (180 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PLEKHD1Pleckstrin homology and coiled-coil domain containing D1. (506 aa)
EIF2S2Eukaryotic translation initiation factor 2 subunit beta. (333 aa)
ABCA5ATP binding cassette subfamily A member 5. (1593 aa)
ENSCPOP00000023065ANK_REP_REGION domain-containing protein. (179 aa)
ENSCPOP00000023107Uncharacterized protein. (109 aa)
PSME1Proteasome activator subunit 1. (249 aa)
ABCB10ATP binding cassette subfamily B member 10. (711 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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