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Prkaca Prkaca LOC100730472 LOC100730472 KCNK2 KCNK2 FGF13 FGF13 ACTG2 ACTG2 TCAP TCAP SCN5A SCN5A CASQ1 CASQ1 CASQ2 CASQ2 MYL1 MYL1 MYH6 MYH6 ENSCPOP00000031664 ENSCPOP00000031664 KCND1 KCND1 LOC100721835 LOC100721835 MAST2 MAST2 MYL6 MYL6 Kcnj2 Kcnj2 KCNE4 KCNE4 ABCC9 ABCC9 AHCYL1 AHCYL1 CAV3 CAV3 ATP2B3 ATP2B3 Camk2d Camk2d ITPR1 ITPR1 VCL VCL MYH3 MYH3 ORAI2 ORAI2 MYH13 MYH13 ATP1A2 ATP1A2 SLC8A3 SLC8A3 KCNK12 KCNK12 MYL12A MYL12A FGF12 FGF12 KCNIP4 KCNIP4 SORBS2 SORBS2 FGF11 FGF11 RYR3 RYR3 ATP1B1 ATP1B1 RYR2 RYR2 NEB NEB Aldh2 Aldh2 FKBP1B FKBP1B TGFB1I1 TGFB1I1 TPM2 TPM2 TRDN TRDN TPM3 TPM3 PLN PLN SCN2B SCN2B ATP1A1 ATP1A1 STIM1 STIM1 PAK1 PAK1 GUCY1A2 GUCY1A2 ASPHD2 ASPHD2 TLN1 TLN1 PXN PXN NPR2 NPR2 TMOD1 TMOD1 MAST4 MAST4 MAST1 MAST1 VIM VIM KCNK1 KCNK1 SORBS3 SORBS3 KCND3 KCND3 ATP2A1 ATP2A1 ACTA1 ACTA1 KCNK10 KCNK10 SLC8A1 SLC8A1 DES DES SCN1A SCN1A SCN2A SCN2A TMOD3 TMOD3 SORBS1 SORBS1 ACTN3 ACTN3 MYLPF MYLPF MYH15 MYH15 TRPC1 TRPC1 TNNC1 TNNC1 STIM2 STIM2 KCNK18 KCNK18 ATP1B3 ATP1B3 SCN4B SCN4B H0V2A9_CAVPO H0V2A9_CAVPO MYH7B MYH7B MYLK MYLK RNF222 RNF222 AKAP9 AKAP9 FER1L5 FER1L5 SDR42E2 SDR42E2 Cacnb2 Cacnb2 PHEX PHEX CAMK2A CAMK2A CORIN CORIN MYH7 MYH7 ASPH ASPH ATP2A3 ATP2A3 CLIC2 CLIC2 SMIM20 SMIM20 MME MME SCN4A SCN4A MYH11 MYH11 PDE5A PDE5A Dnaaf3 Dnaaf3 DMD DMD ITGB5 ITGB5 SCN3A SCN3A MYOF MYOF MMEL1 MMEL1 SLC8A2 SLC8A2 SRI SRI DYSF DYSF ACTC1 ACTC1 Atp1a3 Atp1a3 MYL2 MYL2 Ces1d Ces1d TPM1 TPM1 GUCY1A1 GUCY1A1 MYBPC1 MYBPC1 ACTA2 ACTA2 LPXN LPXN KCND2 KCND2 CACNA1I CACNA1I CACNA1H CACNA1H ITPR2 ITPR2 TMOD2 TMOD2 MYL3 MYL3 SCN9A SCN9A LMOD3 LMOD3 Tpm4 Tpm4 ITGA1 ITGA1 Kcnk7 Kcnk7 ASPHD1 ASPHD1 SCN10A SCN10A ACTN2 ACTN2 SCN7A SCN7A KCNIP1 KCNIP1 MYL9 MYL9 GUCY1B1 GUCY1B1 KCNIP3 KCNIP3 CACNG7 CACNG7 SCN8A SCN8A RYR1 RYR1 H0VU94_CAVPO H0VU94_CAVPO TNNC2 TNNC2 RANGRF RANGRF TNNT1 TNNT1 KCNQ1 KCNQ1 Actl10 Actl10 Kcnj12 Kcnj12 KCNK3 KCNK3 NPPA NPPA KCNJ14 KCNJ14 MYBPC2 MYBPC2 KCNJ4 KCNJ4 TNNI3 TNNI3 Fxyd3 Fxyd3 KCNH2 KCNH2 NKX2-5 NKX2-5 FGF14 FGF14 CACNG4 CACNG4 CAMK2B CAMK2B TRIM72 TRIM72 KCNK9 KCNK9 GATD1 GATD1 TNNT2 TNNT2 NPR1 NPR1 ATP2B2 ATP2B2 MYL4 MYL4 NPPC NPPC TLNRD1 TLNRD1 H0W649_CAVPO H0W649_CAVPO ORAI1 ORAI1 CALD1 CALD1 CACNA2D2 CACNA2D2 KCNK5 KCNK5 KCNA5 KCNA5 KCNK4 KCNK4 ITPR3 ITPR3 KCNJ11 KCNJ11 Fxyd2 Fxyd2 H0WB32_CAVPO H0WB32_CAVPO H0WBR6_CAVPO H0WBR6_CAVPO KCNK15 KCNK15 CACNA1G CACNA1G FXYD1 FXYD1 MYL10 MYL10 SCN1B SCN1B ANXA6 ANXA6 KCNIP2 KCNIP2 CACNA2D1 CACNA2D1 CACNG6 CACNG6 TNNI1 TNNI1 MAST3 MAST3 SCN11A SCN11A MYH8 MYH8 KCNE2 KCNE2 KCNK13 KCNK13 FAHD2A FAHD2A ORAI3 ORAI3 PAK2 PAK2 KCNE3 KCNE3 ATP2B1 ATP2B1 ENSCPOP00000022864 ENSCPOP00000022864 FXYD6 FXYD6 CAMK2G CAMK2G CACNA1C CACNA1C CACNB1 CACNB1 Sln Sln KCNK16 KCNK16 TNNI2 TNNI2 Kcnk6 Kcnk6 LOC100717473 LOC100717473 ATP2B4 ATP2B4 TLN2 TLN2 LMOD2 LMOD2 TNNT3 TNNT3 FXYD7 FXYD7 KCNE1 KCNE1 ATP1A4 ATP1A4 TMOD4 TMOD4 ENSCPOP00000024015 ENSCPOP00000024015 LMOD1 LMOD1 ATP2A2 ATP2A2 ENSCPOP00000024624 ENSCPOP00000024624 ATP1B2 ATP1B2 ENSCPOP00000024842 ENSCPOP00000024842 ENSCPOP00000024925 ENSCPOP00000024925 SCN3B SCN3B MYL6B MYL6B Fxyd4 Fxyd4 MYBPC3 MYBPC3
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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experimentally determined
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gene neighborhood
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gene co-occurrence
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textmining
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PrkacaUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
LOC100730472Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (559 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
ACTG2Actin gamma 2, smooth muscle. (376 aa)
TCAPTitin-cap. (167 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2015 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (408 aa)
MYL1Myosin light chain 1. (189 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
ENSCPOP00000031664Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (702 aa)
KCND1Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (651 aa)
LOC100721835Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa)
MAST2Microtubule associated serine/threonine kinase 2. (1682 aa)
MYL6Myosin light chain 6. (151 aa)
Kcnj2Inward rectifier potassium channel 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Blocked b [...] (427 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (174 aa)
ABCC9ATP binding cassette subfamily C member 9. (1546 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1226 aa)
Camk2dProtein kinase domain-containing protein. (532 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2738 aa)
VCLVinculin. (1134 aa)
MYH3Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
ORAI2ORAI calcium release-activated calcium modulator 2. (307 aa)
MYH13Myosin heavy chain 13; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
KCNK12Potassium two pore domain channel subfamily K member 12; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (424 aa)
MYL12AMyosin light chain 12A. (178 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
KCNIP4Potassium voltage-gated channel interacting protein 4. (143 aa)
SORBS2Sorbin and SH3 domain containing 2. (1204 aa)
FGF11Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa)
RYR3Ryanodine receptor 3. (4843 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity). (306 aa)
RYR2Ryanodine receptor 2. (4910 aa)
NEBNebulin. (7032 aa)
Aldh2Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (521 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa)
TPM2Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
TRDNTriadin. (682 aa)
TPM3Tropomyosin 3; Belongs to the tropomyosin family. (285 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (209 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1048 aa)
STIM1Stromal interaction molecule 1. (713 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (635 aa)
ASPHD2Aspartate beta-hydroxylase domain containing 2. (334 aa)
TLN1Talin 1. (2537 aa)
PXNPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (588 aa)
NPR2Guanylate cyclase. (1047 aa)
TMOD1Tropomodulin 1. (359 aa)
MAST4Microtubule associated serine/threonine kinase family member 4. (2436 aa)
MAST1Microtubule associated serine/threonine kinase 1. (1555 aa)
VIMIF rod domain-containing protein; Belongs to the intermediate filament family. (445 aa)
KCNK1Potassium channel subfamily K member 1; Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but also in kidney and in other tissues. Forms dimeric channels through which potassium ions pass in accordance with their electrochemical gradient. The channel is selective for K(+) ions at physiological potassium concentrations and at neutral pH, but becomes permeable to Na(+) at subphysiological K(+) levels and upon acidification of the extracellular medium. The homodimer has very low potassium [...] (336 aa)
SORBS3Sorbin and SH3 domain containing 3. (685 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (654 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1001 aa)
ACTA1Actin alpha 1, skeletal muscle. (377 aa)
KCNK10Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (535 aa)
SLC8A1Sodium/calcium exchanger 1; Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to Ca(2+) transport during excitation-contraction coupling in muscle. In a first phase, voltage- gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum. SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels r [...] (970 aa)
DESDesmin; Belongs to the intermediate filament family. (475 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1997 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1965 aa)
TMOD3Tropomodulin 3. (352 aa)
SORBS1Sorbin and SH3 domain containing 1. (933 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (889 aa)
MYLPFMyosin light chain, phosphorylatable, fast skeletal muscle. (170 aa)
MYH15Myosin heavy chain 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1926 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (810 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
STIM2Stromal interaction molecule 2. (742 aa)
KCNK18Potassium two pore domain channel subfamily K member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (384 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta-3; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known (By similarity); Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (184 aa)
H0V2A9_CAVPOFXYD domain-containing ion transport regulator; Belongs to the FXYD family. (106 aa)
MYH7BMyosin heavy chain 7B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1941 aa)
MYLKMyosin light chain kinase. (1959 aa)
RNF222Ring finger protein 222. (215 aa)
AKAP9A-kinase anchoring protein 9. (3887 aa)
FER1L5Fer-1 like family member 5. (2020 aa)
SDR42E2Short chain dehydrogenase/reductase family 42E, member 2. (541 aa)
Cacnb2SH3 domain-containing protein. (621 aa)
PHEXPhosphate regulating endopeptidase homolog X-linked. (749 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
CORINCorin, serine peptidase. (980 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1949 aa)
ASPHAspartate beta-hydroxylase. (644 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1028 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (246 aa)
SMIM20Small integral membrane protein 20. (67 aa)
MMEMembrane metalloendopeptidase. (718 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1829 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1982 aa)
PDE5APhosphodiesterase. (863 aa)
Dnaaf3Uncharacterized protein. (525 aa)
DMDDystrophin. (3613 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (801 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1975 aa)
MYOFMyoferlin. (2033 aa)
MMEL1Membrane metalloendopeptidase like 1. (772 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (840 aa)
SRISorcin. (198 aa)
DYSFDysferlin. (2103 aa)
ACTC1Actin alpha cardiac muscle 1. (377 aa)
Atp1a3Sodium/potassium-transporting ATPase subunit alpha. (1028 aa)
MYL2Myosin light chain 2. (167 aa)
Ces1dCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa)
TPM1Uncharacterized protein; Belongs to the tropomyosin family. (288 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
MYBPC1Myosin binding protein C, slow type. (1130 aa)
ACTA2Actin alpha 2, smooth muscle. (377 aa)
LPXNLeupaxin. (381 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2067 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2337 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2622 aa)
TMOD2Tropomodulin 2. (351 aa)
MYL3Myosin light chain 3. (199 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1986 aa)
LMOD3Leiomodin 3. (569 aa)
Tpm4Uncharacterized protein; Belongs to the tropomyosin family. (248 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1168 aa)
Kcnk7Potassium channel subfamily K member. (315 aa)
ASPHD1Aspartate beta-hydroxylase domain containing 1. (367 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1943 aa)
ACTN2Actinin alpha 2. (894 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1520 aa)
KCNIP1Potassium voltage-gated channel interacting protein 1. (227 aa)
MYL9Myosin light chain 9. (172 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (622 aa)
KCNIP3Potassium voltage-gated channel interacting protein 3. (256 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1876 aa)
RYR1Ryanodine receptor 1. (4554 aa)
H0VU94_CAVPOCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (520 aa)
TNNC2Troponin C2, fast skeletal type. (160 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
TNNT1Troponin T1, slow skeletal type. (253 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] (671 aa)
Actl10Uncharacterized protein; Belongs to the actin family. (393 aa)
Kcnj12Uncharacterized protein. (535 aa)
KCNK3Potassium two pore domain channel subfamily K member 3. (270 aa)
NPPACardiodilatin-related peptide; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity). (223 aa)
KCNJ14Inwardly-rectifying potassium channel Kir2.4. (439 aa)
MYBPC2Myosin binding protein C, fast type. (1137 aa)
KCNJ4Uncharacterized protein. (443 aa)
TNNI3Troponin I3, cardiac type. (211 aa)
Fxyd3FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (88 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (By similarity). (1144 aa)
NKX2-5NK2 homeobox 5. (303 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (325 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (659 aa)
TRIM72Tripartite motif containing 72. (477 aa)
KCNK9Potassium channel subfamily K member 9; pH-dependent, voltage-insensitive, background potassium channel protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (365 aa)
GATD1Glutamine amidotransferase like class 1 domain containing 1. (220 aa)
TNNT2Uncharacterized protein. (296 aa)
NPR1Guanylate cyclase. (881 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1296 aa)
MYL4Myosin light chain 4. (195 aa)
NPPCNatriuretic peptide C. (126 aa)
TLNRD1Talin rod domain containing 1. (355 aa)
H0W649_CAVPOVoltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (280 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (302 aa)
CALD1Caldesmon 1. (742 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1129 aa)
KCNK5Potassium two pore domain channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (458 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (609 aa)
KCNK4Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (392 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2663 aa)
KCNJ11ATP-sensitive inward rectifier potassium channel 11; This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Can form cardiac and smo [...] (390 aa)
Fxyd2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa)
H0WB32_CAVPOSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (177 aa)
H0WBR6_CAVPOUncharacterized protein; Belongs to the actin family. (381 aa)
KCNK15Potassium two pore domain channel subfamily K member 15; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (326 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2372 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa)
MYL10Myosin light chain 10. (147 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (216 aa)
ANXA6Annexin. (753 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (270 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1078 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (257 aa)
TNNI1Troponin I1, slow skeletal type. (189 aa)
MAST3Microtubule associated serine/threonine kinase 3. (1369 aa)
SCN11ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1719 aa)
MYH8Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
KCNE2Potassium voltage-gated channel subfamily E member 2; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-t [...] (123 aa)
KCNK13Potassium two pore domain channel subfamily K member 13; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (405 aa)
FAHD2AFumarylacetoacetate hydrolase domain containing 2A. (313 aa)
ORAI3ORAI calcium release-activated calcium modulator 3. (297 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (105 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
ENSCPOP00000022864I-set domain-containing protein. (610 aa)
FXYD6FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (95 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (545 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2089 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (641 aa)
SlnUncharacterized protein. (31 aa)
KCNK16Potassium two pore domain channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (300 aa)
TNNI2Troponin I2, fast skeletal type. (190 aa)
Kcnk6Potassium channel subfamily K member. (312 aa)
LOC100717473Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (561 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1207 aa)
TLN2Talin 2. (2542 aa)
LMOD2Leiomodin 2. (525 aa)
TNNT3Troponin T3, fast skeletal type. (276 aa)
FXYD7FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (80 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with K [...] (125 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1030 aa)
TMOD4Tropomodulin 4. (345 aa)
ENSCPOP00000024015Uncharacterized protein. (5460 aa)
LMOD1Leiomodin 1. (595 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
ENSCPOP00000024624Uncharacterized protein. (493 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (252 aa)
ENSCPOP00000024842Uncharacterized protein. (173 aa)
ENSCPOP00000024925COesterase domain-containing protein. (295 aa)
SCN3BSodium voltage-gated channel beta subunit 3. (215 aa)
MYL6BMyosin light chain 6B. (207 aa)
Fxyd4FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (86 aa)
MYBPC3Myosin binding protein C, cardiac. (1298 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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