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| | Kcnk7 | Potassium channel subfamily K member. (315 aa) |
| | ASPHD1 | Aspartate beta-hydroxylase domain containing 1. (367 aa) |
| | SCN10A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1943 aa) |
| | ACTN2 | Actinin alpha 2. (894 aa) |
| | SCN7A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1520 aa) |
| | KCNIP1 | Potassium voltage-gated channel interacting protein 1. (227 aa) |
| | MYL9 | Myosin light chain 9. (172 aa) |
| | GUCY1B1 | Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (622 aa) |
| | KCNIP3 | Potassium voltage-gated channel interacting protein 3. (256 aa) |
| | CACNG7 | Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa) |
| | SCN8A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1876 aa) |
| | RYR1 | Ryanodine receptor 1. (4554 aa) |
| | H0VU94_CAVPO | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (520 aa) |
| | TNNC2 | Troponin C2, fast skeletal type. (160 aa) |
| | RANGRF | RAN guanine nucleotide release factor. (186 aa) |
| | TNNT1 | Troponin T1, slow skeletal type. (253 aa) |
| | KCNQ1 | Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] (671 aa) |
| | Actl10 | Uncharacterized protein; Belongs to the actin family. (393 aa) |
| | Kcnj12 | Uncharacterized protein. (535 aa) |
| | KCNK3 | Potassium two pore domain channel subfamily K member 3. (270 aa) |
| | NPPA | Cardiodilatin-related peptide; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity). (223 aa) |
| | KCNJ14 | Inwardly-rectifying potassium channel Kir2.4. (439 aa) |
| | MYBPC2 | Myosin binding protein C, fast type. (1137 aa) |
| | KCNJ4 | Uncharacterized protein. (443 aa) |
| | TNNI3 | Troponin I3, cardiac type. (211 aa) |
| | Fxyd3 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (88 aa) |
| | KCNH2 | Potassium voltage-gated channel subfamily H member 2; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (By similarity). (1144 aa) |
| | NKX2-5 | NK2 homeobox 5. (303 aa) |
| | FGF14 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa) |
| | CACNG4 | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (325 aa) |
| | CAMK2B | Calcium/calmodulin dependent protein kinase II beta. (659 aa) |
| | TRIM72 | Tripartite motif containing 72. (477 aa) |
| | KCNK9 | Potassium channel subfamily K member 9; pH-dependent, voltage-insensitive, background potassium channel protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (365 aa) |
| | GATD1 | Glutamine amidotransferase like class 1 domain containing 1. (220 aa) |
| | TNNT2 | Uncharacterized protein. (296 aa) |
| | NPR1 | Guanylate cyclase. (881 aa) |
| | ATP2B2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1296 aa) |
| | MYL4 | Myosin light chain 4. (195 aa) |
| | NPPC | Natriuretic peptide C. (126 aa) |
| | TLNRD1 | Talin rod domain containing 1. (355 aa) |
| | H0W649_CAVPO | Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (280 aa) |
| | ORAI1 | ORAI calcium release-activated calcium modulator 1. (302 aa) |
| | MYL2 | Myosin light chain 2. (167 aa) |
| | Atp1a3 | Sodium/potassium-transporting ATPase subunit alpha. (1028 aa) |
| | ACTC1 | Actin alpha cardiac muscle 1. (377 aa) |
| | DYSF | Dysferlin. (2103 aa) |
| | SRI | Sorcin. (198 aa) |
| | SLC8A2 | Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (840 aa) |
| | MMEL1 | Membrane metalloendopeptidase like 1. (772 aa) |
| | MYOF | Myoferlin. (2033 aa) |
| | SCN3A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1975 aa) |
| | ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (801 aa) |
| | DMD | Dystrophin. (3613 aa) |
| | Dnaaf3 | Uncharacterized protein. (525 aa) |
| | PDE5A | Phosphodiesterase. (863 aa) |
| | MYH11 | Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1982 aa) |
| | SCN4A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1829 aa) |
| | MME | Membrane metalloendopeptidase. (718 aa) |
| | SMIM20 | Small integral membrane protein 20. (67 aa) |
| | KCNA5 | Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (609 aa) |
| | KCNK5 | Potassium two pore domain channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (458 aa) |
| | CACNA2D2 | Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1129 aa) |
| | CALD1 | Caldesmon 1. (742 aa) |
| | MYH7 | Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1949 aa) |
| | ASPH | Aspartate beta-hydroxylase. (644 aa) |
| | ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1028 aa) |
| | CLIC2 | Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (246 aa) |
| | VCL | Vinculin. (1134 aa) |
| | MYH3 | Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa) |
| | ORAI2 | ORAI calcium release-activated calcium modulator 2. (307 aa) |
| | MYH13 | Myosin heavy chain 13; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa) |
| | ATP1A2 | Sodium/potassium-transporting ATPase subunit alpha. (1020 aa) |
| | KCNK4 | Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (392 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2663 aa) |
| | KCNJ11 | ATP-sensitive inward rectifier potassium channel 11; This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Can form cardiac and smo [...] (390 aa) |
| | Fxyd2 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa) |
| | H0WB32_CAVPO | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (177 aa) |
| | H0WBR6_CAVPO | Uncharacterized protein; Belongs to the actin family. (381 aa) |
| | KCNK15 | Potassium two pore domain channel subfamily K member 15; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (326 aa) |
| | CACNA1G | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2372 aa) |
| | FXYD1 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa) |
| | MYL10 | Myosin light chain 10. (147 aa) |
| | SCN1B | Sodium voltage-gated channel beta subunit 1. (216 aa) |
| | ANXA6 | Annexin. (753 aa) |
| | KCNIP2 | Potassium voltage-gated channel interacting protein 2. (270 aa) |
| | CACNA2D1 | Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1078 aa) |
| | CACNG6 | Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (257 aa) |
| | TNNI1 | Troponin I1, slow skeletal type. (189 aa) |
| | MAST3 | Microtubule associated serine/threonine kinase 3. (1369 aa) |
| | SCN11A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1719 aa) |
| | MYH8 | Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa) |
| | KCNE2 | Potassium voltage-gated channel subfamily E member 2; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-t [...] (123 aa) |
| | KCNK13 | Potassium two pore domain channel subfamily K member 13; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (405 aa) |
| | FAHD2A | Fumarylacetoacetate hydrolase domain containing 2A. (313 aa) |
| | ORAI3 | ORAI calcium release-activated calcium modulator 3. (297 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | KCNE3 | Potassium voltage-gated channel subfamily E regulatory subunit 3. (105 aa) |
| | ATP2B1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa) |
| | ENSCPOP00000022864 | I-set domain-containing protein. (610 aa) |
| | FXYD6 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (95 aa) |
| | CAMK2G | Calcium/calmodulin dependent protein kinase II gamma. (545 aa) |
| | CACNA1C | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2089 aa) |
| | CACNB1 | Calcium voltage-gated channel auxiliary subunit beta 1. (641 aa) |
| | Sln | Uncharacterized protein. (31 aa) |
| | KCNK16 | Potassium two pore domain channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (300 aa) |
| | TNNI2 | Troponin I2, fast skeletal type. (190 aa) |
| | Kcnk6 | Potassium channel subfamily K member. (312 aa) |
| | LOC100717473 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (561 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1207 aa) |
| | TLN2 | Talin 2. (2542 aa) |
| | LMOD2 | Leiomodin 2. (525 aa) |
| | TNNT3 | Troponin T3, fast skeletal type. (276 aa) |
| | FXYD7 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (80 aa) |
| | CORIN | Corin, serine peptidase. (980 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa) |
| | PHEX | Phosphate regulating endopeptidase homolog X-linked. (749 aa) |
| | Cacnb2 | SH3 domain-containing protein. (621 aa) |
| | SDR42E2 | Short chain dehydrogenase/reductase family 42E, member 2. (541 aa) |
| | FER1L5 | Fer-1 like family member 5. (2020 aa) |
| | AKAP9 | A-kinase anchoring protein 9. (3887 aa) |
| | RNF222 | Ring finger protein 222. (215 aa) |
| | MYLK | Myosin light chain kinase. (1959 aa) |
| | MYH7B | Myosin heavy chain 7B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1941 aa) |
| | H0V2A9_CAVPO | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (106 aa) |
| | SCN4B | Sodium voltage-gated channel beta subunit 4. (184 aa) |
| | ATP1B3 | Sodium/potassium-transporting ATPase subunit beta-3; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known (By similarity); Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa) |
| | KCNK18 | Potassium two pore domain channel subfamily K member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (384 aa) |
| | STIM2 | Stromal interaction molecule 2. (742 aa) |
| | TNNC1 | Troponin C1, slow skeletal and cardiac type. (161 aa) |
| | TRPC1 | Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (810 aa) |
| | MYH15 | Myosin heavy chain 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1926 aa) |
| | MYLPF | Myosin light chain, phosphorylatable, fast skeletal muscle. (170 aa) |
| | ACTN3 | Actinin alpha 3 (gene/pseudogene). (889 aa) |
| | SORBS1 | Sorbin and SH3 domain containing 1. (933 aa) |
| | TMOD3 | Tropomodulin 3. (352 aa) |
| | SCN2A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1965 aa) |
| | SCN1A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1997 aa) |
| | DES | Desmin; Belongs to the intermediate filament family. (475 aa) |
| | SLC8A1 | Sodium/calcium exchanger 1; Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to Ca(2+) transport during excitation-contraction coupling in muscle. In a first phase, voltage- gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum. SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels r [...] (970 aa) |
| | KCNK10 | Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (535 aa) |
| | ACTA1 | Actin alpha 1, skeletal muscle. (377 aa) |
| | ATP2A1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1001 aa) |
| | KCND3 | Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (654 aa) |
| | SORBS3 | Sorbin and SH3 domain containing 3. (685 aa) |
| | KCNK1 | Potassium channel subfamily K member 1; Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but also in kidney and in other tissues. Forms dimeric channels through which potassium ions pass in accordance with their electrochemical gradient. The channel is selective for K(+) ions at physiological potassium concentrations and at neutral pH, but becomes permeable to Na(+) at subphysiological K(+) levels and upon acidification of the extracellular medium. The homodimer has very low potassium [...] (336 aa) |
| | SLC8A3 | Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa) |
| | VIM | IF rod domain-containing protein; Belongs to the intermediate filament family. (445 aa) |
| | MAST1 | Microtubule associated serine/threonine kinase 1. (1555 aa) |
| | MAST4 | Microtubule associated serine/threonine kinase family member 4. (2436 aa) |
| | TMOD1 | Tropomodulin 1. (359 aa) |
| | NPR2 | Guanylate cyclase. (1047 aa) |
| | PXN | Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (588 aa) |
| | TLN1 | Talin 1. (2537 aa) |
| | ASPHD2 | Aspartate beta-hydroxylase domain containing 2. (334 aa) |
| | GUCY1A2 | Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (635 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (544 aa) |
| | KCNK2 | Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa) |
| | Prkaca | Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa) |
| | LOC100730472 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (559 aa) |
| | FGF13 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa) |
| | ACTG2 | Actin gamma 2, smooth muscle. (376 aa) |
| | KCNK12 | Potassium two pore domain channel subfamily K member 12; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (424 aa) |
| | MYL12A | Myosin light chain 12A. (178 aa) |
| | FGF12 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa) |
| | KCNIP4 | Potassium voltage-gated channel interacting protein 4. (143 aa) |
| | SORBS2 | Sorbin and SH3 domain containing 2. (1204 aa) |
| | FGF11 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa) |
| | RYR3 | Ryanodine receptor 3. (4843 aa) |
| | ATP1B1 | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity). (306 aa) |
| | RYR2 | Ryanodine receptor 2. (4910 aa) |
| | NEB | Nebulin. (7032 aa) |
| | Aldh2 | Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (521 aa) |
| | FKBP1B | Peptidylprolyl isomerase. (108 aa) |
| | TGFB1I1 | Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa) |
| | TPM2 | Uncharacterized protein; Belongs to the tropomyosin family. (284 aa) |
| | TRDN | Triadin. (682 aa) |
| | TPM3 | Tropomyosin 3; Belongs to the tropomyosin family. (285 aa) |
| | PLN | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa) |
| | SCN2B | Sodium voltage-gated channel beta subunit 2. (209 aa) |
| | ATP1A1 | Sodium/potassium-transporting ATPase subunit alpha. (1048 aa) |
| | STIM1 | Stromal interaction molecule 1. (713 aa) |
| | MYBPC3 | Myosin binding protein C, cardiac. (1298 aa) |
| | Fxyd4 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (86 aa) |
| | MYL6B | Myosin light chain 6B. (207 aa) |
| | SCN3B | Sodium voltage-gated channel beta subunit 3. (215 aa) |
| | ENSCPOP00000024925 | COesterase domain-containing protein. (295 aa) |
| | ENSCPOP00000024842 | Uncharacterized protein. (173 aa) |
| | ATP1B2 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (252 aa) |
| | ENSCPOP00000024624 | Uncharacterized protein. (493 aa) |
| | ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa) |
| | LMOD1 | Leiomodin 1. (595 aa) |
| | ENSCPOP00000024015 | Uncharacterized protein. (5460 aa) |
| | TMOD4 | Tropomodulin 4. (345 aa) |
| | TCAP | Titin-cap. (167 aa) |
| | SCN5A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2015 aa) |
| | CASQ1 | Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa) |
| | CASQ2 | Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (408 aa) |
| | MYL1 | Myosin light chain 1. (189 aa) |
| | MYH6 | Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa) |
| | ENSCPOP00000031664 | Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (702 aa) |
| | KCND1 | Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (651 aa) |
| | LOC100721835 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa) |
| | MAST2 | Microtubule associated serine/threonine kinase 2. (1682 aa) |
| | MYL6 | Myosin light chain 6. (151 aa) |
| | Kcnj2 | Inward rectifier potassium channel 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Blocked b [...] (427 aa) |
| | KCNE4 | Potassium voltage-gated channel subfamily E regulatory subunit 4. (174 aa) |
| | ABCC9 | ATP binding cassette subfamily C member 9. (1546 aa) |
| | AHCYL1 | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa) |
| | CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa) |
| | ATP2B3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1226 aa) |
| | Camk2d | Protein kinase domain-containing protein. (532 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2738 aa) |
| | ATP1A4 | Sodium/potassium-transporting ATPase subunit alpha. (1030 aa) |
| | KCNE1 | Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with K [...] (125 aa) |
| | Ces1d | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa) |
| | TPM1 | Uncharacterized protein; Belongs to the tropomyosin family. (288 aa) |
| | GUCY1A1 | Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa) |
| | MYBPC1 | Myosin binding protein C, slow type. (1130 aa) |
| | ACTA2 | Actin alpha 2, smooth muscle. (377 aa) |
| | LPXN | Leupaxin. (381 aa) |
| | KCND2 | Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa) |
| | CACNA1I | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2067 aa) |
| | CACNA1H | Calcium voltage-gated channel subunit alpha1 H. (2337 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2622 aa) |
| | TMOD2 | Tropomodulin 2. (351 aa) |
| | MYL3 | Myosin light chain 3. (199 aa) |
| | SCN9A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1986 aa) |
| | LMOD3 | Leiomodin 3. (569 aa) |
| | Tpm4 | Uncharacterized protein; Belongs to the tropomyosin family. (248 aa) |
| | ITGA1 | Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1168 aa) |
