STRINGSTRING
DPP6 DPP6 ISL1 ISL1 GRP GRP GIP GIP ALX3 ALX3 DPP9 DPP9 H0W0R3_CAVPO H0W0R3_CAVPO GNB3 GNB3 DPP8 DPP8 FFAR4 FFAR4 DPP10 DPP10 GNB1 GNB1 PAX6 PAX6 DPP4 DPP4 LEP LEP CDX2 CDX2 ISL2 ISL2 GNG13 GNG13 FAP FAP LOC100721783 LOC100721783 GCG GCG GNAT3 GNAT3 Ffar1 Ffar1 GPR119 GPR119
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DPP6Dipeptidyl peptidase like 6; Belongs to the peptidase S9B family. (864 aa)
ISL1ISL LIM homeobox 1. (349 aa)
GRPGastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family. (143 aa)
GIPGastric inhibitory polypeptide. (145 aa)
ALX3ALX homeobox 3. (343 aa)
DPP9Dipeptidyl peptidase 9; Belongs to the peptidase S9B family. (863 aa)
H0W0R3_CAVPOHomeobox domain-containing protein. (134 aa)
GNB3G protein subunit beta 3. (340 aa)
DPP8Dipeptidyl peptidase 8; Belongs to the peptidase S9B family. (891 aa)
FFAR4Free fatty acid receptor 4. (363 aa)
DPP10Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family. (776 aa)
GNB1Beta-transducin. (340 aa)
PAX6Paired box 6. (436 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (764 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (165 aa)
CDX2Caudal type homeobox 2. (314 aa)
ISL2ISL LIM homeobox 2. (358 aa)
GNG13G protein subunit gamma 13. (67 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (725 aa)
LOC100721783G_PROTEIN_RECEP_F1_2 domain-containing protein. (300 aa)
GCGGlicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] (180 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
Ffar1annotation not available (300 aa)
GPR119G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. (335 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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