STRINGSTRING
CASR CASR RGS13 RGS13 HRAS HRAS TBXA2R TBXA2R HTR2A HTR2A GRK2 GRK2 FFAR2 FFAR2 LPAR6 LPAR6 KISS1 KISS1 CSDE1 CSDE1 HCRT HCRT GPR132 GPR132 RGS19 RGS19 RGS5 RGS5 PROK1 PROK1 GRB2 GRB2 AVPR1B AVPR1B ENSCPOP00000031524 ENSCPOP00000031524 GPR17 GPR17 GNGT2 GNGT2 GPR68 GPR68 LPAR3 LPAR3 ADRA1A ADRA1A BTK BTK AVPR1A AVPR1A LPAR2 LPAR2 RGS16 RGS16 TACR1 TACR1 ITPR1 ITPR1 ENSCPOP00000030509 ENSCPOP00000030509 LOC100722106 LOC100722106 HTR2C HTR2C NTSR1 NTSR1 P2RY6 P2RY6 LOC100734206 LOC100734206 DGKG DGKG DGKQ DGKQ F2 F2 PLCB2 PLCB2 GNG4 GNG4 PTGFR PTGFR PLCB4 PLCB4 EDN1 EDN1 OXTR OXTR PTAFR PTAFR EDN3 EDN3 ENSCPOP00000028569 ENSCPOP00000028569 Ltb4r2 Ltb4r2 GNG8 GNG8 DGKE DGKE TRPC7 TRPC7 P2RY2 P2RY2 PRKCQ PRKCQ REEP3 REEP3 GNAQ GNAQ RGS4 RGS4 Gng5 Gng5 LOC100719924 LOC100719924 QRFP QRFP PROKR2 PROKR2 GNG12 GNG12 PROKR1 PROKR1 MGLL MGLL PRKCD PRKCD PROK2 PROK2 GNB4 GNB4 Ccl14 Ccl14 GNG11 GNG11 NPFF NPFF PTGER1 PTGER1 DGKZ DGKZ F2R F2R GNG2 GNG2 F2RL1 F2RL1 F2RL3 F2RL3 MAPK3 MAPK3 LPAR1 LPAR1 RPH3AL RPH3AL ABHD6 ABHD6 PLCB1 PLCB1 RPS6KA1 RPS6KA1 RGS3 RGS3 LOC100714756 LOC100714756 MMP3 MMP3 GNG7 GNG7 ADRA1D ADRA1D RPS6KA3 RPS6KA3 GOLT1B GOLT1B RPS6KA2 RPS6KA2 LOC101788094 LOC101788094 LOC100733450 LOC100733450 TRIO TRIO GNG3 GNG3 LOC100717354 LOC100717354 CCK CCK LOC100718750 LOC100718750 DGKI DGKI GNA11 GNA11 PLCB3 PLCB3 RGS2 RGS2 CREB1 CREB1 AGT AGT LOC100721472 LOC100721472 LOC100733576 LOC100733576 LOC100719959 LOC100719959 H0WDB6_CAVPO H0WDB6_CAVPO GPR65 GPR65 LOC100729898 LOC100729898 APP APP LOC100713256 LOC100713256 LOC100721750 LOC100721750 Arhgef25 Arhgef25 H0WCC4_CAVPO H0WCC4_CAVPO H0WBW4_CAVPO H0WBW4_CAVPO BDKRB2 BDKRB2 NPFFR1 NPFFR1 H0WBT9_CAVPO H0WBT9_CAVPO ADRA1B ADRA1B H0WBQ2_CAVPO H0WBQ2_CAVPO LOC100716890 LOC100716890 TRPC6 TRPC6 LOC100716808 LOC100716808 GHRL GHRL MAPK7 MAPK7 ITPR3 ITPR3 H0W907_CAVPO H0W907_CAVPO DOC2B DOC2B LOC100722787 LOC100722787 LOC100717081 LOC100717081 LOC100726503 LOC100726503 CHRM1 CHRM1 GPR174 GPR174 H0W731_CAVPO H0W731_CAVPO LOC100726752 LOC100726752 H0W692_CAVPO H0W692_CAVPO LOC100722661 LOC100722661 LOC100721959 LOC100721959 LOC100716855 LOC100716855 LOC100714069 LOC100714069 P2RY10 P2RY10 GPR19 GPR19 LOC100733119 LOC100733119 GRP GRP DOC2A DOC2A XCR1 XCR1 LOC100734246 LOC100734246 LOC100718849 LOC100718849 LOC100731137 LOC100731137 GNB3 GNB3 H0W2U5_CAVPO H0W2U5_CAVPO HRH1 HRH1 Chrm3 Chrm3 H0W1T8_CAVPO H0W1T8_CAVPO P2RY11 P2RY11 RGS21 RGS21 H0W0Z0_CAVPO H0W0Z0_CAVPO H0W076_CAVPO H0W076_CAVPO H0W027_CAVPO H0W027_CAVPO LOC100719125 LOC100719125 H0VZZ1_CAVPO H0VZZ1_CAVPO NPS NPS GCGR GCGR CCKBR CCKBR GNB2 GNB2 LTB4R LTB4R H0VYF2_CAVPO H0VYF2_CAVPO AVP AVP Ffar1 Ffar1 H0VX22_CAVPO H0VX22_CAVPO Kiss1r Kiss1r LOC100734527 LOC100734527 H0VW99_CAVPO H0VW99_CAVPO CYSLTR2 CYSLTR2 TACR3 TACR3 H0VVN2_CAVPO H0VVN2_CAVPO LOC101787631 LOC101787631 H0VVJ6_CAVPO H0VVJ6_CAVPO H0VVC7_CAVPO H0VVC7_CAVPO LOC100719167 LOC100719167 GCG GCG H0VV33_CAVPO H0VV33_CAVPO PRKCE PRKCE P2RY1 P2RY1 RPH3A RPH3A GNRH1 GNRH1 EDNRB EDNRB LOC100721783 LOC100721783 H0VSA2_CAVPO H0VSA2_CAVPO ABHD12B ABHD12B RGS1 RGS1 GNRHR GNRHR ANXA1 ANXA1 BRS3 BRS3 SDHAF3 SDHAF3 GHSR GHSR GNB5 GNB5 EGFR EGFR HTR2B HTR2B GRPR GRPR DGKK DGKK OPN4 OPN4 TRPC3 TRPC3 QRFPR QRFPR NMBR NMBR OXT OXT CYSLTR1 CYSLTR1 FFAR4 FFAR4 REEP2 REEP2 SOS1 SOS1 F2RL2 F2RL2 CHRM5 CHRM5 REEP4 REEP4 RGS17 RGS17 GRM1 GRM1 ABHD12 ABHD12 NMS NMS GPR39 GPR39 GOLT1A GOLT1A EDNRA EDNRA Gna15 Gna15 CDHR1 CDHR1 GNA14 GNA14 GNB1 GNB1 NPSR1 NPSR1 PCDH1 PCDH1 TACR2 TACR2 DGKH DGKH RGS18 RGS18 HCRTR2 HCRTR2 PIK3CA PIK3CA NTS NTS Uts2r Uts2r CCKAR CCKAR HCRTR1 HCRTR1 GPR143 GPR143 AGTR1 AGTR1 PIK3R1 PIK3R1 MLN MLN GNGT1 GNGT1 DAGLB DAGLB NMU NMU GRM5 GRM5 RGSL1 RGSL1 DGKD DGKD Prkch Prkch Gast Gast DGKA DGKA Nmur2 Nmur2 GNG13 GNG13 PMCH PMCH HBEGF HBEGF NRAS NRAS KRAS KRAS EDN2 EDN2 TAC1 TAC1 TRHR TRHR FAP FAP MCHR1 MCHR1 KALRN KALRN ITPR2 ITPR2 KNG1 KNG1 DAGLA DAGLA TAC3 TAC3 NMB NMB MAPK1 MAPK1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Known Interactions
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experimentally determined
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CASRCalcium sensing receptor. (1071 aa)
RGS13Regulator of G protein signaling 13. (158 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
TBXA2RThromboxane A2 receptor. (347 aa)
HTR2A5-hydroxytryptamine receptor 2A; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5- dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. S [...] (470 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (750 aa)
FFAR2Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (330 aa)
LPAR6Lysophosphatidic acid receptor 6; Belongs to the G-protein coupled receptor 1 family. (343 aa)
KISS1KiSS-1 metastasis suppressor. (128 aa)
CSDE1Cold shock domain-containing protein E1; RNA-binding protein. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain (By similarity). (779 aa)
HCRTHypocretin neuropeptide precursor. (110 aa)
GPR132G protein-coupled receptor 132; Belongs to the G-protein coupled receptor 1 family. (383 aa)
RGS19Regulator of G protein signaling 19. (216 aa)
RGS5Regulator of G protein signaling 5. (181 aa)
PROK1Prokineticin 1. (105 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (422 aa)
ENSCPOP00000031524Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (100 aa)
GPR17G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family. (339 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (363 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (353 aa)
ADRA1AAlpha-1A adrenergic receptor; This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes (By similarity). (466 aa)
BTKTyrosine-protein kinase. (659 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (418 aa)
LPAR2Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (348 aa)
RGS16Regulator of G protein signaling 16. (202 aa)
TACR1Substance-P receptor; This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. (407 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2738 aa)
ENSCPOP00000030509Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC100722106G_PROTEIN_RECEP_F3_4 domain-containing protein. (831 aa)
HTR2C5-hydroxytryptamine receptor 2C. (458 aa)
NTSR1Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (412 aa)
P2RY6Pyrimidinergic receptor P2Y6. (328 aa)
LOC100734206Uncharacterized protein. (461 aa)
DGKGDiacylglycerol kinase. (792 aa)
DGKQDiacylglycerol kinase. (947 aa)
F2Coagulation factor II, thrombin; Belongs to the peptidase S1 family. (664 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PTGFRProstaglandin F receptor; Belongs to the G-protein coupled receptor 1 family. (365 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
EDN1Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (208 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (390 aa)
PTAFRPlatelet-activating factor receptor; Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. (342 aa)
EDN3Endothelin 3. (200 aa)
ENSCPOP00000028569ANF_receptor domain-containing protein. (260 aa)
Ltb4r2G_PROTEIN_RECEP_F1_2 domain-containing protein. (360 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
DGKEDiacylglycerol kinase. (575 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
P2RY2Purinergic receptor P2Y2; Belongs to the G-protein coupled receptor 1 family. (376 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (705 aa)
REEP3Receptor expression-enhancing protein. (244 aa)
GNAQG protein subunit alpha q. (313 aa)
RGS4Regulator of G protein signaling 4. (205 aa)
Gng5G protein gamma domain-containing protein. (41 aa)
LOC100719924G_PROTEIN_RECEP_F3_4 domain-containing protein. (788 aa)
QRFPPyroglutamylated RFamide peptide. (125 aa)
PROKR2Prokineticin receptor 2; Belongs to the G-protein coupled receptor 1 family. (384 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PROKR1Prokineticin receptor 1; Belongs to the G-protein coupled receptor 1 family. (393 aa)
MGLLMonoglyceride lipase. (314 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
PROK2Prokineticin 2. (131 aa)
GNB4G protein subunit beta 4. (340 aa)
Ccl14C-C motif chemokine. (94 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
NPFFNeuropeptide FF-amide peptide precursor. (109 aa)
PTGER1Prostaglandin E receptor 1. (405 aa)
DGKZDiacylglycerol kinase. (1118 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (426 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
F2RL1F2R like trypsin receptor 1. (399 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (381 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
RPH3ALRabphilin 3A like (without C2 domains). (303 aa)
ABHD6Abhydrolase domain containing 6. (337 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1217 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
RGS3Regulator of G protein signaling 3. (919 aa)
LOC100714756SCY domain-containing protein. (114 aa)
MMP3Matrix metallopeptidase 3. (479 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
ADRA1DAdrenoceptor alpha 1D. (478 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
GOLT1BGolgi transport 1B. (138 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
LOC101788094C-C motif chemokine. (125 aa)
LOC100733450G_PROTEIN_RECEP_F3_4 domain-containing protein. (789 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (3062 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC100717354G_PROTEIN_RECEP_F3_4 domain-containing protein. (886 aa)
CCKCholecystokinin. (115 aa)
LOC100718750Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (133 aa)
DGKIDiacylglycerol kinase. (957 aa)
GNA11G protein subunit alpha 11. (345 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1227 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
AGTAngiotensinogen; Belongs to the serpin family. (477 aa)
LOC100721472G_PROTEIN_RECEP_F3_4 domain-containing protein. (888 aa)
LOC100733576G_PROTEIN_RECEP_F3_4 domain-containing protein. (792 aa)
LOC100719959G_PROTEIN_RECEP_F3_4 domain-containing protein; Belongs to the G-protein coupled receptor 3 family. (811 aa)
H0WDB6_CAVPOG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (288 aa)
GPR65G protein-coupled receptor 65; Belongs to the G-protein coupled receptor 1 family. (334 aa)
LOC100729898G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (366 aa)
APPGamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (770 aa)
LOC100713256G_PROTEIN_RECEP_F3_4 domain-containing protein. (797 aa)
LOC100721750G_PROTEIN_RECEP_F3_4 domain-containing protein. (713 aa)
Arhgef25Uncharacterized protein. (574 aa)
H0WCC4_CAVPOG_PROTEIN_RECEP_F3_4 domain-containing protein. (853 aa)
H0WBW4_CAVPOGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
BDKRB2B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). (399 aa)
NPFFR1Neuropeptide FF receptor 1; Belongs to the G-protein coupled receptor 1 family. (436 aa)
H0WBT9_CAVPOG_PROTEIN_RECEP_F3_4 domain-containing protein. (816 aa)
ADRA1BAdrenoceptor alpha 1B. (520 aa)
H0WBQ2_CAVPOUncharacterized protein. (282 aa)
LOC100716890G_PROTEIN_RECEP_F3_4 domain-containing protein. (785 aa)
TRPC6Uncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (934 aa)
LOC100716808G_PROTEIN_RECEP_F3_4 domain-containing protein. (856 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (797 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2663 aa)
H0W907_CAVPOG_PROTEIN_RECEP_F3_4 domain-containing protein. (798 aa)
DOC2BDouble C2 domain beta. (340 aa)
LOC100722787G_PROTEIN_RECEP_F3_4 domain-containing protein. (788 aa)
LOC100717081G_PROTEIN_RECEP_F3_4 domain-containing protein. (710 aa)
LOC100726503G_PROTEIN_RECEP_F3_4 domain-containing protein. (782 aa)
CHRM1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
GPR174G protein-coupled receptor 174. (333 aa)
H0W731_CAVPOG_PROTEIN_RECEP_F3_4 domain-containing protein. (783 aa)
LOC100726752G_PROTEIN_RECEP_F3_4 domain-containing protein. (855 aa)
H0W692_CAVPOG_PROTEIN_RECEP_F3_4 domain-containing protein. (785 aa)
LOC100722661G_PROTEIN_RECEP_F3_4 domain-containing protein. (785 aa)
LOC100721959G_PROTEIN_RECEP_F3_4 domain-containing protein. (815 aa)
LOC100716855Brix domain-containing protein. (368 aa)
LOC100714069G_PROTEIN_RECEP_F3_4 domain-containing protein. (769 aa)
P2RY10P2Y receptor family member 10. (328 aa)
GPR19G protein-coupled receptor 19. (415 aa)
LOC100733119G_PROTEIN_RECEP_F3_4 domain-containing protein. (790 aa)
GRPGastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family. (143 aa)
DOC2ADouble C2-like domain-containing protein. (401 aa)
XCR1X-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (333 aa)
LOC100734246G_PROTEIN_RECEP_F3_4 domain-containing protein. (791 aa)
LOC100718849G_PROTEIN_RECEP_F3_4 domain-containing protein. (674 aa)
LOC100731137G_PROTEIN_RECEP_F3_4 domain-containing protein. (786 aa)
GNB3G protein subunit beta 3. (340 aa)
H0W2U5_CAVPOG_PROTEIN_RECEP_F3_4 domain-containing protein. (803 aa)
HRH1Histamine H1 receptor; In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system. (482 aa)
Chrm3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
H0W1T8_CAVPOG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (347 aa)
P2RY11Purinergic receptor P2Y11; Belongs to the G-protein coupled receptor 1 family. (408 aa)
RGS21Regulator of G protein signaling 21. (152 aa)
H0W0Z0_CAVPOG_PROTEIN_RECEP_F3_4 domain-containing protein. (747 aa)
H0W076_CAVPOG_PROTEIN_RECEP_F3_4 domain-containing protein. (824 aa)
H0W027_CAVPOUncharacterized protein. (722 aa)
LOC100719125G_PROTEIN_RECEP_F3_4 domain-containing protein. (859 aa)
H0VZZ1_CAVPOANF_receptor domain-containing protein. (444 aa)
NPSNeuropeptide S. (72 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (481 aa)
CCKBRCholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family. (426 aa)
GNB2G protein subunit beta 2. (378 aa)
LTB4RLeukotriene B4 receptor; Belongs to the G-protein coupled receptor 1 family. (348 aa)
H0VYF2_CAVPOG_PROTEIN_RECEP_F3_4 domain-containing protein. (764 aa)
AVPVasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin; Belongs to the vasopressin/oxytocin family. (159 aa)
Ffar1annotation not available (300 aa)
H0VX22_CAVPOC-C motif chemokine. (93 aa)
Kiss1rG_PROTEIN_RECEP_F1_2 domain-containing protein. (363 aa)
LOC100734527Double C2-like domain-containing protein. (399 aa)
H0VW99_CAVPOG_PROTEIN_RECEP_F3_4 domain-containing protein. (811 aa)
CYSLTR2Cysteinyl leukotriene receptor 2. (317 aa)
TACR3Neuromedin-K receptor; This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. (404 aa)
H0VVN2_CAVPOG_PROTEIN_RECEP_F3_4 domain-containing protein; Belongs to the G-protein coupled receptor 3 family. (777 aa)
LOC101787631G_PROTEIN_RECEP_F3_4 domain-containing protein. (871 aa)
H0VVJ6_CAVPOUncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (1247 aa)
H0VVC7_CAVPOG_PROTEIN_RECEP_F3_4 domain-containing protein. (772 aa)
LOC100719167G_PROTEIN_RECEP_F3_4 domain-containing protein. (787 aa)
GCGGlicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] (180 aa)
H0VV33_CAVPOG_PROTEIN_RECEP_F3_4 domain-containing protein. (763 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
P2RY1P2Y purinoceptor 1; Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. Belongs to the G-protein coupled receptor 1 family. (373 aa)
RPH3ARabphilin 3A. (667 aa)
GNRH1GnRH-associated peptide 1; Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones; Belongs to the GnRH family. (92 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (415 aa)
LOC100721783G_PROTEIN_RECEP_F1_2 domain-containing protein. (300 aa)
H0VSA2_CAVPOUncharacterized protein. (52 aa)
ABHD12BAbhydrolase domain containing 12B. (328 aa)
RGS1Regulator of G protein signaling 1. (209 aa)
GNRHRGonadotropin-releasing hormone receptor; Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G- proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. (328 aa)
ANXA1Annexin. (346 aa)
BRS3Bombesin receptor subtype-3; Role in sperm cell division, maturation, or function. The relative order of ligand affinity is GRP = neuromedin-C >> neuromedin- B. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. (399 aa)
SDHAF3Succinate dehydrogenase complex assembly factor 3. (126 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (302 aa)
GNB5G protein subunit beta 5. (406 aa)
EGFRReceptor protein-tyrosine kinase. (1214 aa)
HTR2B5-hydroxytryptamine receptor 2B; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide- binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity [...] (480 aa)
GRPRGastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family. (383 aa)
DGKKDiacylglycerol kinase. (1062 aa)
OPN4Opsin 4. (471 aa)
TRPC3ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (849 aa)
QRFPRPyroglutamylated RFamide peptide receptor; Belongs to the G-protein coupled receptor 1 family. (431 aa)
NMBRNeuromedin B receptor; Belongs to the G-protein coupled receptor 1 family. (390 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (125 aa)
CYSLTR1Cysteinyl leukotriene receptor 1; Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity). (340 aa)
FFAR4Free fatty acid receptor 4. (363 aa)
REEP2Receptor expression-enhancing protein. (254 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1276 aa)
F2RL2Coagulation factor II thrombin receptor like 2. (329 aa)
CHRM5Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (530 aa)
REEP4Receptor expression-enhancing protein. (257 aa)
RGS17Regulator of G protein signaling 17. (210 aa)
GRM1Glutamate metabotropic receptor 1. (1195 aa)
ABHD12Abhydrolase domain containing 12. (397 aa)
NMSNeuromedin S. (150 aa)
GPR39G protein-coupled receptor 39; Belongs to the G-protein coupled receptor 1 family. (295 aa)
GOLT1AGolgi transport 1A. (127 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (399 aa)
Gna15Uncharacterized protein. (205 aa)
CDHR1Cadherin related family member 1. (857 aa)
GNA14G protein subunit alpha 14. (356 aa)
GNB1Beta-transducin. (340 aa)
NPSR1Neuropeptide S receptor 1. (377 aa)
PCDH1Protocadherin 1. (1249 aa)
TACR2Substance-K receptor; This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. (402 aa)
DGKHDiacylglycerol kinase. (1144 aa)
RGS18Regulator of G protein signaling 18. (235 aa)
HCRTR2Hypocretin receptor 2; Belongs to the G-protein coupled receptor 1 family. (448 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1044 aa)
NTSNeurotensin. (170 aa)
Uts2rG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (386 aa)
CCKARCholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). (430 aa)
HCRTR1Hypocretin receptor 1; Belongs to the G-protein coupled receptor 1 family. (416 aa)
GPR143G protein-coupled receptor 143. (407 aa)
AGTR1Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system (By similarity); Belongs to the G-protein coupled receptor 1 family. (359 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
MLNMotilin-associated peptide; Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle. (121 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
DAGLBDiacylglycerol lipase beta. (672 aa)
NMUNeuromedin-U-9. (171 aa)
GRM5Glutamate metabotropic receptor 5. (873 aa)
RGSL1Regulator of G protein signaling like 1. (1037 aa)
DGKDDiacylglycerol kinase. (1160 aa)
PrkchUncharacterized protein. (543 aa)
GastBig gastrin; Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine; Belongs to the gastrin/cholecystokinin family. (96 aa)
DGKADiacylglycerol kinase. (736 aa)
Nmur2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (403 aa)
GNG13G protein subunit gamma 13. (67 aa)
PMCHPro-melanin concentrating hormone. (165 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
NRASGTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
EDN2Endothelin 2. (179 aa)
TAC1Substance P. (129 aa)
TRHRThyrotropin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (393 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (725 aa)
MCHR1Melanin concentrating hormone receptor 1. (355 aa)
KALRNKalirin RhoGEF kinase. (2964 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2622 aa)
KNG1Kininogen 1. (625 aa)
DAGLADiacylglycerol lipase alpha. (1037 aa)
TAC3Tachykinin 3. (125 aa)
NMBNeuromedin B. (119 aa)
MAPK1Mitogen-activated protein kinase. (325 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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