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DCP1A DCP1A Lsm4 Lsm4 CNOT4 CNOT4 CNOT11 CNOT11 LSM5 LSM5 PABPC3 PABPC3 PAN3 PAN3 ENSCPOP00000030783 ENSCPOP00000030783 LSM1 LSM1 Eif4b Eif4b EIF4A3 EIF4A3 PABPC4L PABPC4L TNKS1BP1 TNKS1BP1 EIF4A2 EIF4A2 LOC100728313 LOC100728313 EXOSC2 EXOSC2 ENSCPOP00000028770 ENSCPOP00000028770 LSM3 LSM3 ENSCPOP00000028322 ENSCPOP00000028322 LSM6 LSM6 ENSCPOP00000028144 ENSCPOP00000028144 EIF4E EIF4E EXOSC5 EXOSC5 CNOT9 CNOT9 CNOT6 CNOT6 EXOSC1 EXOSC1 ENSCPOP00000025764 ENSCPOP00000025764 DIS3 DIS3 TOE1 TOE1 ENSCPOP00000024917 ENSCPOP00000024917 PABPC4 PABPC4 EDC4 EDC4 ENSCPOP00000024505 ENSCPOP00000024505 EXOSC9 EXOSC9 TENT2 TENT2 CNOT3 CNOT3 Exosc6 Exosc6 CNOT7 CNOT7 PARN PARN ENSCPOP00000022264 ENSCPOP00000022264 HIGD1B HIGD1B EXOSC4 EXOSC4 LSM2 LSM2 PNLDC1 PNLDC1 NT5C3B NT5C3B WDR61 WDR61 EDC3 EDC3 PAN2 PAN2 DCPS DCPS Tut1 Tut1 LSM7 LSM7 TTC37 TTC37 PABPC1L PABPC1L CNOT1 CNOT1 TMC7 TMC7 DDX6 DDX6 CNOT6L CNOT6L C19orf54 C19orf54 EXOSC3 EXOSC3 EIF4G1 EIF4G1 HBS1L HBS1L PATL1 PATL1 CNOT10 CNOT10 DCP1B DCP1B DIS3L2 DIS3L2 TUT4 TUT4 EXOSC7 EXOSC7 EIF4A1 EIF4A1 CNOT2 CNOT2 EXOSC8 EXOSC8 EIF4E1B EIF4E1B MTPAP MTPAP CNOT8 CNOT8 LRRC27 LRRC27 PATL2 PATL2 Paip1 Paip1 TUT7 TUT7 DCP2 DCP2 SKIV2L SKIV2L DIS3L DIS3L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DCP1ADecapping mRNA 1A. (601 aa)
Lsm4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa)
CNOT4CCR4-NOT transcription complex subunit 4. (710 aa)
CNOT11CCR4-NOT transcription complex subunit 11. (515 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
PABPC3Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (586 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (751 aa)
ENSCPOP00000030783MIF4G domain-containing protein. (390 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
Eif4bRRM domain-containing protein. (611 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
PABPC4LPoly(A) binding protein cytoplasmic 4 like. (359 aa)
TNKS1BP1Tankyrase 1 binding protein 1. (1731 aa)
EIF4A2Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family. (407 aa)
LOC100728313RNase_PH domain-containing protein. (256 aa)
EXOSC2Exosome component 2. (293 aa)
ENSCPOP00000028770Q_MOTIF domain-containing protein. (85 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
ENSCPOP00000028322RRM domain-containing protein. (576 aa)
LSM6LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
ENSCPOP00000028144Q_MOTIF domain-containing protein. (93 aa)
EIF4EEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
EXOSC5Exosome component 5. (240 aa)
CNOT9CCR4-NOT transcription complex subunit 9. (299 aa)
CNOT6CCR4-NOT transcription complex subunit 6. (534 aa)
EXOSC1Exosome component 1. (195 aa)
ENSCPOP00000025764MIF4G domain-containing protein. (404 aa)
DIS3DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (987 aa)
TOE1Target of EGR1, exonuclease. (509 aa)
ENSCPOP00000024917Uncharacterized protein; Belongs to the DEAD box helicase family. (315 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
EDC4Enhancer of mRNA decapping 4. (1405 aa)
ENSCPOP00000024505Helicase C-terminal domain-containing protein. (162 aa)
EXOSC9Exosome component 9. (439 aa)
TENT2Terminal nucleotidyltransferase 2. (484 aa)
CNOT3CCR4-NOT transcription complex subunit 3. (751 aa)
Exosc6RNase_PH domain-containing protein. (246 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
PARNPoly(A)-specific ribonuclease. (637 aa)
ENSCPOP00000022264Uncharacterized protein. (566 aa)
HIGD1BHIG1 hypoxia inducible domain family member 1B. (99 aa)
EXOSC4Exosome component 4. (245 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
PNLDC1PARN like, ribonuclease domain containing 1. (518 aa)
NT5C3B5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (337 aa)
WDR61WD repeat domain 61. (305 aa)
EDC3Enhancer of mRNA decapping 3. (508 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1204 aa)
DCPSDecapping enzyme, scavenger. (337 aa)
Tut1RRM domain-containing protein. (852 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa)
TTC37Tetratricopeptide repeat domain 37. (1595 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (618 aa)
CNOT1CCR4-NOT transcription complex subunit 1. (2294 aa)
TMC7Transmembrane channel-like protein. (653 aa)
DDX6Probable ATP-dependent RNA helicase DDX6; In the process of mRNA degradation, may play a role in mRNA decapping. (474 aa)
CNOT6LCCR4-NOT transcription complex subunit 6 like. (462 aa)
C19orf54Chromosome 19 open reading frame 54. (319 aa)
EXOSC3Exosome component 3. (275 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1579 aa)
HBS1LHBS1 like translational GTPase. (623 aa)
PATL1PAT1 homolog 1, processing body mRNA decay factor. (790 aa)
CNOT10CCR4-NOT transcription complex subunit 10. (754 aa)
DCP1BDecapping mRNA 1B. (592 aa)
DIS3L2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (877 aa)
TUT4Terminal uridylyl transferase 4. (1584 aa)
EXOSC7Exosome component 7. (291 aa)
EIF4A1Eukaryotic translation initiation factor 4A1; Belongs to the DEAD box helicase family. (400 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (544 aa)
EXOSC8Exosome component 8. (276 aa)
EIF4E1BEukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (246 aa)
MTPAPMitochondrial poly(A) polymerase. (627 aa)
CNOT8CCR4-NOT transcription complex subunit 8. (292 aa)
LRRC27Leucine rich repeat containing 27. (508 aa)
PATL2PAT1 homolog 2. (517 aa)
Paip1MIF4G domain-containing protein. (399 aa)
TUT7Terminal uridylyl transferase 7. (1514 aa)
DCP2Decapping mRNA 2. (422 aa)
SKIV2LSki2 like RNA helicase. (1239 aa)
DIS3LDIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1055 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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