STRINGSTRING
IKBKG IKBKG H0WAS6_CAVPO H0WAS6_CAVPO H0WAD6_CAVPO H0WAD6_CAVPO ALPK1 ALPK1 NFKB1 NFKB1 Rps27a Rps27a NFKBIA NFKBIA NFKB2 NFKB2 TRAF6 TRAF6 TAB3 TAB3 VWC2 VWC2 LRRC71 LRRC71 IRAK2 IRAK2 AGER AGER Usp18 Usp18 UBA52 UBA52 LOC106026468 LOC106026468 LRRC34 LRRC34 LRRC74A LRRC74A TAB2 TAB2 UBE2V1 UBE2V1 LRRC45 LRRC45 NFKBIB NFKBIB KHNYN KHNYN TONSL TONSL IRAK1 IRAK1 ENSCPOP00000032088 ENSCPOP00000032088 CHUK CHUK Ubc Ubc ENSCPOP00000031632 ENSCPOP00000031632 NKIRAS2 NKIRAS2 ENSCPOP00000030838 ENSCPOP00000030838 MAP3K20 MAP3K20 CASP8 CASP8 UBB UBB ENSCPOP00000029546 ENSCPOP00000029546 NLRX1 NLRX1 LRRC74B LRRC74B ENSCPOP00000027005 ENSCPOP00000027005 TIFA TIFA S100B S100B TRAF2 TRAF2 MAP3K7 MAP3K7 NKIRAS1 NKIRAS1 Hmgb1 Hmgb1 USP14 USP14 ENSCPOP00000023362 ENSCPOP00000023362 N4BP1 N4BP1 RELA RELA CASP10 CASP10 LRRC14 LRRC14 NLRC5 NLRC5 IKBKB IKBKB LOC100718750 LOC100718750 H0WDT2_CAVPO H0WDT2_CAVPO APP APP TAB1 TAB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (416 aa)
H0WAS6_CAVPOUncharacterized protein. (214 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
ALPK1Alpha kinase 1. (1117 aa)
NFKB1Nuclear factor kappa B subunit 1. (967 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
NFKB2Nuclear factor kappa B subunit 2. (854 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (679 aa)
VWC2Von Willebrand factor C domain containing 2. (315 aa)
LRRC71Leucine rich repeat containing 71. (548 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (606 aa)
AGERAdvanced glycosylation end-product specific receptor. (377 aa)
Usp18USP domain-containing protein; Belongs to the peptidase C19 family. (158 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
LOC106026468UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (174 aa)
LRRC34Leucine rich repeat containing 34. (448 aa)
LRRC74ALeucine rich repeat containing 74A. (465 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (665 aa)
UBE2V1Ubiquitin conjugating enzyme E2 V1. (145 aa)
LRRC45Leucine rich repeat containing 45. (669 aa)
NFKBIBNFKB inhibitor beta. (355 aa)
KHNYNKH and NYN domain containing. (657 aa)
TONSLTonsoku like, DNA repair protein. (1395 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (707 aa)
ENSCPOP00000032088Uncharacterized protein. (191 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (749 aa)
UbcUncharacterized protein. (159 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (191 aa)
ENSCPOP00000030838UBIQUITIN_CONJUGAT_2 domain-containing protein. (133 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (711 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (481 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
ENSCPOP00000029546UBIQUITIN_CONJUGAT_2 domain-containing protein. (140 aa)
NLRX1NLR family member X1. (976 aa)
LRRC74BLeucine rich repeat containing 74B. (380 aa)
ENSCPOP00000027005UBIQUITIN_CONJUGAT_2 domain-containing protein. (83 aa)
TIFATRAF interacting protein with forkhead associated domain. (185 aa)
S100BProtein S100; Belongs to the S-100 family. (92 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
NKIRAS1NFKB inhibitor interacting Ras like 1. (192 aa)
Hmgb1annotation not available (215 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (493 aa)
ENSCPOP00000023362UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
N4BP1NEDD4 binding protein 1. (886 aa)
RELARELA proto-oncogene, NF-kB subunit. (549 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (474 aa)
LRRC14Leucine rich repeat containing 14. (493 aa)
NLRC5NLR family CARD domain containing 5. (1831 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (739 aa)
LOC100718750Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (133 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
APPGamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (770 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (507 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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