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TAB1 TAB1 IKBKG IKBKG H0WAD6_CAVPO H0WAD6_CAVPO MAP2K7 MAP2K7 TAB2 TAB2 MAPK10 MAPK10 NOD2 NOD2 IRAK1 IRAK1 Ubc Ubc ENSCPOP00000031632 ENSCPOP00000031632 ENSCPOP00000030838 ENSCPOP00000030838 MAP3K20 MAP3K20 UBB UBB ENSCPOP00000029546 ENSCPOP00000029546 ENSCPOP00000027005 ENSCPOP00000027005 MAP3K7 MAP3K7 MAP2K4 MAP2K4 MAPK9 MAPK9 NOD1 NOD1 MAPK8 MAPK8 ENSCPOP00000023362 ENSCPOP00000023362 H0WDT2_CAVPO H0WDT2_CAVPO UBE2V1 UBE2V1 LOC106026468 LOC106026468 RIPK2 RIPK2 Rps27a Rps27a TRAF6 TRAF6 TAB3 TAB3 IRAK2 IRAK2 UBA52 UBA52
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (507 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (416 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (459 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (665 aa)
MAPK10Mitogen-activated protein kinase 10. (434 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1018 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (707 aa)
UbcUncharacterized protein. (159 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
ENSCPOP00000030838UBIQUITIN_CONJUGAT_2 domain-containing protein. (133 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (711 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
ENSCPOP00000029546UBIQUITIN_CONJUGAT_2 domain-containing protein. (140 aa)
ENSCPOP00000027005UBIQUITIN_CONJUGAT_2 domain-containing protein. (83 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (386 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (873 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ENSCPOP00000023362UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
UBE2V1Ubiquitin conjugating enzyme E2 V1. (145 aa)
LOC106026468UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (174 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (442 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (679 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (606 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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