22 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DCP1A	Decapping mRNA 1A. (601 aa)
	Xrn1	5'-3' exoribonuclease 1. (1386 aa)
	DCP2	Decapping mRNA 2. (422 aa)
	LOC100728313	RNase_PH domain-containing protein. (256 aa)
	EXOSC2	Exosome component 2. (293 aa)
	ZFP36L1	ZFP36 ring finger protein like 1. (338 aa)
	EXOSC5	Exosome component 5. (240 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	EXOSC1	Exosome component 1. (195 aa)
	DIS3	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (987 aa)
	YWHAB	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
	EXOSC9	Exosome component 9. (439 aa)
	EXOSC8	Exosome component 8. (276 aa)
	DIS3L	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1055 aa)
	Exosc6	RNase_PH domain-containing protein. (246 aa)
	ENSCPOP00000023532	XRN_N domain-containing protein. (103 aa)
	EXOSC4	Exosome component 4. (245 aa)
	ZFP36L2	ZFP36 ring finger protein like 2. (403 aa)
	MAPKAPK2	MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (383 aa)
	EXOSC3	Exosome component 3. (275 aa)
	DIS3L2	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (877 aa)
	EXOSC7	Exosome component 7. (291 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	MAPKAPK2	ENSCPOP00000026115	ENSCPOP00000016007	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	MAPK activated protein kinase 2; Belongs to the protein kinase superfamily.	0.746
AKT1	YWHAB	ENSCPOP00000026115	ENSCPOP00000024562	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.	0.509
AKT1	ZFP36L1	ENSCPOP00000026115	ENSCPOP00000028707	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	ZFP36 ring finger protein like 1.	0.635
AKT1	ZFP36L2	ENSCPOP00000026115	ENSCPOP00000017715	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	ZFP36 ring finger protein like 2.	0.635
DCP1A	DCP2	ENSCPOP00000000063	ENSCPOP00000001487	Decapping mRNA 1A.	Decapping mRNA 2.	0.993
DCP1A	DIS3	ENSCPOP00000000063	ENSCPOP00000025401	Decapping mRNA 1A.	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	0.750
DCP1A	DIS3L	ENSCPOP00000000063	ENSCPOP00000000221	Decapping mRNA 1A.	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	0.718
DCP1A	DIS3L2	ENSCPOP00000000063	ENSCPOP00000004679	Decapping mRNA 1A.	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...]	0.718
DCP1A	ENSCPOP00000023532	ENSCPOP00000000063	ENSCPOP00000023532	Decapping mRNA 1A.	XRN_N domain-containing protein.	0.967
DCP1A	EXOSC1	ENSCPOP00000000063	ENSCPOP00000025770	Decapping mRNA 1A.	Exosome component 1.	0.708
DCP1A	EXOSC2	ENSCPOP00000000063	ENSCPOP00000028957	Decapping mRNA 1A.	Exosome component 2.	0.722
DCP1A	EXOSC3	ENSCPOP00000000063	ENSCPOP00000007756	Decapping mRNA 1A.	Exosome component 3.	0.693
DCP1A	EXOSC4	ENSCPOP00000000063	ENSCPOP00000019053	Decapping mRNA 1A.	Exosome component 4.	0.737
DCP1A	EXOSC5	ENSCPOP00000000063	ENSCPOP00000026447	Decapping mRNA 1A.	Exosome component 5.	0.777
DCP1A	EXOSC9	ENSCPOP00000000063	ENSCPOP00000024499	Decapping mRNA 1A.	Exosome component 9.	0.693
DCP1A	Exosc6	ENSCPOP00000000063	ENSCPOP00000023812	Decapping mRNA 1A.	RNase_PH domain-containing protein.	0.685
DCP1A	LOC100728313	ENSCPOP00000000063	ENSCPOP00000028974	Decapping mRNA 1A.	RNase_PH domain-containing protein.	0.685
DCP1A	Xrn1	ENSCPOP00000000063	ENSCPOP00000003123	Decapping mRNA 1A.	5'-3' exoribonuclease 1.	0.967
DCP1A	ZFP36L1	ENSCPOP00000000063	ENSCPOP00000028707	Decapping mRNA 1A.	ZFP36 ring finger protein like 1.	0.707
DCP1A	ZFP36L2	ENSCPOP00000000063	ENSCPOP00000017715	Decapping mRNA 1A.	ZFP36 ring finger protein like 2.	0.707