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| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | PPP4R4 | Protein phosphatase 4 regulatory subunit 4. (832 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (271 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2283 aa) |
| | TFDP1 | Transcription factor. (411 aa) |
| | Ccne2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (405 aa) |
| | Skp2 | F-box domain-containing protein. (424 aa) |
| | CDC7 | Cell division cycle 7. (560 aa) |
| | FNDC3B | Fibronectin type III domain containing 3B. (1101 aa) |
| | LYN | Tyrosine-protein kinase. (512 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (322 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (350 aa) |
| | CABLES1 | Cdk5 and Abl enzyme substrate 1. (443 aa) |
| | E2F4 | E2F transcription factor 4. (411 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (429 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (579 aa) |
| | DYRK1B | Dual specificity tyrosine phosphorylation regulated kinase 1B. (680 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) |
| | FNBP4 | Formin binding protein 4. (1044 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | PSMB8 | Proteasome subunit beta. (273 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (810 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | CDKN2B | Cyclin dependent kinase inhibitor 2B. (131 aa) |
| | RBL1 | RB transcriptional corepressor like 1. (1051 aa) |
| | PSMB6 | Proteasome subunit beta. (239 aa) |
| | MEIOB | Meiosis specific with OB-fold. (471 aa) |
| | PPP4R1 | Protein phosphatase 4 regulatory subunit 1. (942 aa) |
| | Pola2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | POLA1 | DNA polymerase. (1467 aa) |
| | PPP2R3A | Protein phosphatase 2 regulatory subunit B''alpha. (1122 aa) |
| | WEE1 | Wee1-like protein kinase. (612 aa) |
| | LIN52 | Lin-52 DREAM MuvB core complex component. (91 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (446 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (315 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | FNDC3A | Fibronectin type III domain containing 3A. (1172 aa) |
| | LIN37 | Lin-37 DREAM MuvB core complex component. (246 aa) |
| | ORC6 | Origin recognition complex subunit 6. (293 aa) |
| | PRIM2 | DNA primase subunit 2. (432 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) |
| | ORC2 | Origin recognition complex subunit 2. (577 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma. (453 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (410 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (837 aa) |
| | SKP1 | S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...] (162 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (308 aa) |
| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1117 aa) |
| | Rps27a | Ubiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (389 aa) |
| | RBL2 | RB transcriptional corepressor like 2. (1095 aa) |
| | PTK6 | Tyrosine-protein kinase. (451 aa) |
| | MCM10 | Minichromosome maintenance 10 replication initiation factor. (834 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | GMNN | Geminin DNA replication inhibitor. (209 aa) |
| | DBF4 | DBF4 zinc finger. (675 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (419 aa) |
| | LOC100734047 | Uncharacterized protein. (567 aa) |
| | RB1 | RB transcriptional corepressor 1. (840 aa) |
| | E2F2 | E2F transcription factor 2. (431 aa) |
| | RPA2 | Replication protein A2. (270 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (898 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | ENSCPOP00000032613 | F-box domain-containing protein. (390 aa) |
| | PSME3 | Proteasome activator subunit 3. (254 aa) |
| | Psma2 | Proteasome subunit alpha type. (234 aa) |
| | Ubc | Uncharacterized protein. (159 aa) |
| | PSME2 | Proteasome activator subunit 2. (239 aa) |
| | ENSCPOP00000031632 | Ubiquitin-like domain-containing protein. (141 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | ENSCPOP00000030815 | CAF1C_H4-bd domain-containing protein. (54 aa) |
| | ENSCPOP00000030705 | CYCLIN domain-containing protein; Belongs to the cyclin family. (341 aa) |
| | ENSCPOP00000030079 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (70 aa) |
| | UBB | Polyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | ENSCPOP00000029251 | Uncharacterized protein; Belongs to the SKP1 family. (147 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | CDKN2D | Cyclin dependent kinase inhibitor 2D. (166 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (377 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | Mcm8 | MCM domain-containing protein; Belongs to the MCM family. (833 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | E2F3 | E2F transcription factor 3. (457 aa) |
| | CDKN2C | Cyclin dependent kinase inhibitor 2C. (168 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | E2F1 | E2F transcription factor 1. (389 aa) |
| | LIN9 | Lin-9 DREAM MuvB core complex component. (557 aa) |
| | LIN54 | Lin-54 DREAM MuvB core complex component. (749 aa) |
| | ENSCPOP00000026334 | WD_REPEATS_REGION domain-containing protein. (385 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (169 aa) |
| | Tm4sf19 | Uncharacterized protein. (232 aa) |
| | CDC45 | Cell division cycle 45. (566 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (696 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | ORC5 | Origin recognition complex subunit 5. (414 aa) |
| | CCNH | Cyclin H; Belongs to the cyclin family. (325 aa) |
| | PSME1 | Proteasome activator subunit 1. (249 aa) |
| | ENSCPOP00000023065 | ANK_REP_REGION domain-containing protein. (179 aa) |
| | TESMIN | Testis expressed metallothionein like protein. (387 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | POLE3 | DNA polymerase epsilon 3, accessory subunit. (147 aa) |
| | DYRK1A | Dual specificity tyrosine phosphorylation regulated kinase 1A. (763 aa) |
| | TFDP2 | Transcription factor. (446 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | POLE4 | DNA polymerase epsilon 4, accessory subunit. (116 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | LOC100733575 | Uncharacterized protein. (295 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (420 aa) |
| | H0WDT2_CAVPO | Ubiquitin-like domain-containing protein. (127 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | H0WAD6_CAVPO | Ubiquitin-like domain-containing protein. (111 aa) |
| | H0W9U2_CAVPO | Uncharacterized protein. (143 aa) |
| | H0W9P9_CAVPO | Wee1-like protein kinase. (551 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (504 aa) |
| | PSMB3 | Proteasome subunit beta. (207 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (549 aa) |
| | MYBL2 | MYB proto-oncogene like 2. (699 aa) |
| | H0W6R4_CAVPO | WD_REPEATS_REGION domain-containing protein. (418 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (731 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | Psmd9 | PDZ domain-containing protein. (223 aa) |
| | Ccnd2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (288 aa) |
| | H0W160_CAVPO | Uncharacterized protein. (589 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | CDKN2A | Cyclin dependent kinase inhibitor 2A. (134 aa) |
| | H0VWS1_CAVPO | ANK_REP_REGION domain-containing protein. (213 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (211 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (458 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (448 aa) |
| | Prim1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (419 aa) |
| | Wee2 | Wee1-like protein kinase. (557 aa) |
| | AKT3 | AKT serine/threonine kinase 3. (470 aa) |
| | Rbbp4 | WD_REPEATS_REGION domain-containing protein. (425 aa) |
| | RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1097 aa) |
| | PSMA1 | Proteasome subunit alpha type. (270 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (263 aa) |
| | ORC3 | Origin recognition complex subunit 3. (710 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (534 aa) |
| | Psmd10 | ANK_REP_REGION domain-containing protein. (232 aa) |
| | CDK7 | Cyclin dependent kinase 7. (335 aa) |
| | JAK2 | Tyrosine-protein kinase. (1035 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa) |
| | PSMA7 | Proteasome endopeptidase complex. (248 aa) |
