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| | KCNK18 | Potassium two pore domain channel subfamily K member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (384 aa) |
| | KCNK2 | Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa) |
| | Prkaca | Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa) |
| | LOC100730472 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (559 aa) |
| | FGF13 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa) |
| | SCN5A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2015 aa) |
| | CASQ1 | Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa) |
| | CASQ2 | Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (408 aa) |
| | KCND1 | Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (651 aa) |
| | LOC100721835 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa) |
| | MAST2 | Microtubule associated serine/threonine kinase 2. (1682 aa) |
| | Kcnj2 | Inward rectifier potassium channel 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Blocked b [...] (427 aa) |
| | KCNE4 | Potassium voltage-gated channel subfamily E regulatory subunit 4. (174 aa) |
| | ABCC9 | ATP binding cassette subfamily C member 9. (1546 aa) |
| | AHCYL1 | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa) |
| | ATP2B3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1226 aa) |
| | Camk2d | Protein kinase domain-containing protein. (532 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2738 aa) |
| | ORAI2 | ORAI calcium release-activated calcium modulator 2. (307 aa) |
| | ATP1A2 | Sodium/potassium-transporting ATPase subunit alpha. (1020 aa) |
| | SLC8A3 | Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa) |
| | KCNK12 | Potassium two pore domain channel subfamily K member 12; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (424 aa) |
| | FGF12 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa) |
| | KCNIP4 | Potassium voltage-gated channel interacting protein 4. (143 aa) |
| | FGF11 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa) |
| | RYR3 | Ryanodine receptor 3. (4843 aa) |
| | ATP1B1 | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity). (306 aa) |
| | RYR2 | Ryanodine receptor 2. (4910 aa) |
| | FKBP1B | Peptidylprolyl isomerase. (108 aa) |
| | TRDN | Triadin. (682 aa) |
| | PLN | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa) |
| | SCN2B | Sodium voltage-gated channel beta subunit 2. (209 aa) |
| | ATP1A1 | Sodium/potassium-transporting ATPase subunit alpha. (1048 aa) |
| | STIM1 | Stromal interaction molecule 1. (713 aa) |
| | Fxyd4 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (86 aa) |
| | SCN3B | Sodium voltage-gated channel beta subunit 3. (215 aa) |
| | ENSCPOP00000024925 | COesterase domain-containing protein. (295 aa) |
| | ATP1B2 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (252 aa) |
| | ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa) |
| | ATP1A4 | Sodium/potassium-transporting ATPase subunit alpha. (1030 aa) |
| | KCNE1 | Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with K [...] (125 aa) |
| | FXYD7 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (80 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1207 aa) |
| | LOC100717473 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (561 aa) |
| | Kcnk6 | Potassium channel subfamily K member. (312 aa) |
| | KCNK16 | Potassium two pore domain channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (300 aa) |
| | Sln | Uncharacterized protein. (31 aa) |
| | CACNB1 | Calcium voltage-gated channel auxiliary subunit beta 1. (641 aa) |
| | CACNA1C | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2089 aa) |
| | CAMK2G | Calcium/calmodulin dependent protein kinase II gamma. (545 aa) |
| | FXYD6 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (95 aa) |
| | ATP2B1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa) |
| | KCNE3 | Potassium voltage-gated channel subfamily E regulatory subunit 3. (105 aa) |
| | ORAI3 | ORAI calcium release-activated calcium modulator 3. (297 aa) |
| | FAHD2A | Fumarylacetoacetate hydrolase domain containing 2A. (313 aa) |
| | KCNK13 | Potassium two pore domain channel subfamily K member 13; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (405 aa) |
| | KCNE2 | Potassium voltage-gated channel subfamily E member 2; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-t [...] (123 aa) |
| | SCN11A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1719 aa) |
| | MAST3 | Microtubule associated serine/threonine kinase 3. (1369 aa) |
| | CACNG6 | Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (257 aa) |
| | CACNA2D1 | Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1078 aa) |
| | KCNIP2 | Potassium voltage-gated channel interacting protein 2. (270 aa) |
| | SCN1B | Sodium voltage-gated channel beta subunit 1. (216 aa) |
| | FXYD1 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa) |
| | KCNK15 | Potassium two pore domain channel subfamily K member 15; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (326 aa) |
| | H0WB32_CAVPO | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (177 aa) |
| | Fxyd2 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa) |
| | KCNJ11 | ATP-sensitive inward rectifier potassium channel 11; This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Can form cardiac and smo [...] (390 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2663 aa) |
| | KCNK4 | Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (392 aa) |
| | KCNA5 | Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (609 aa) |
| | KCNK5 | Potassium two pore domain channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (458 aa) |
| | CACNA2D2 | Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1129 aa) |
| | ORAI1 | ORAI calcium release-activated calcium modulator 1. (302 aa) |
| | H0W649_CAVPO | Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (280 aa) |
| | NPPC | Natriuretic peptide C. (126 aa) |
| | ATP2B2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1296 aa) |
| | NPR1 | Guanylate cyclase. (881 aa) |
| | KCNK9 | Potassium channel subfamily K member 9; pH-dependent, voltage-insensitive, background potassium channel protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (365 aa) |
| | CAMK2B | Calcium/calmodulin dependent protein kinase II beta. (659 aa) |
| | CACNG4 | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (325 aa) |
| | FGF14 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa) |
| | NKX2-5 | NK2 homeobox 5. (303 aa) |
| | KCNH2 | Potassium voltage-gated channel subfamily H member 2; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (By similarity). (1144 aa) |
| | Fxyd3 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (88 aa) |
| | TNNI3 | Troponin I3, cardiac type. (211 aa) |
| | KCNJ4 | Uncharacterized protein. (443 aa) |
| | KCNJ14 | Inwardly-rectifying potassium channel Kir2.4. (439 aa) |
| | NPPA | Cardiodilatin-related peptide; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity). (223 aa) |
| | KCNK3 | Potassium two pore domain channel subfamily K member 3. (270 aa) |
| | Kcnj12 | Uncharacterized protein. (535 aa) |
| | KCNQ1 | Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] (671 aa) |
| | RANGRF | RAN guanine nucleotide release factor. (186 aa) |
| | H0VU94_CAVPO | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (520 aa) |
| | RYR1 | Ryanodine receptor 1. (4554 aa) |
| | SCN8A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1876 aa) |
| | CACNG7 | Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa) |
| | KCNIP3 | Potassium voltage-gated channel interacting protein 3. (256 aa) |
| | KCNIP1 | Potassium voltage-gated channel interacting protein 1. (227 aa) |
| | SCN7A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1520 aa) |
| | SCN10A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1943 aa) |
| | ASPHD1 | Aspartate beta-hydroxylase domain containing 1. (367 aa) |
| | Kcnk7 | Potassium channel subfamily K member. (315 aa) |
| | SCN9A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1986 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2622 aa) |
| | KCND2 | Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa) |
| | Ces1d | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa) |
| | Atp1a3 | Sodium/potassium-transporting ATPase subunit alpha. (1028 aa) |
| | SRI | Sorcin. (198 aa) |
| | SLC8A2 | Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (840 aa) |
| | MMEL1 | Membrane metalloendopeptidase like 1. (772 aa) |
| | SCN3A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1975 aa) |
| | SCN4A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1829 aa) |
| | MME | Membrane metalloendopeptidase. (718 aa) |
| | CLIC2 | Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (246 aa) |
| | ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1028 aa) |
| | ASPH | Aspartate beta-hydroxylase. (644 aa) |
| | CORIN | Corin, serine peptidase. (980 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa) |
| | PHEX | Phosphate regulating endopeptidase homolog X-linked. (749 aa) |
| | Cacnb2 | SH3 domain-containing protein. (621 aa) |
| | SDR42E2 | Short chain dehydrogenase/reductase family 42E, member 2. (541 aa) |
| | AKAP9 | A-kinase anchoring protein 9. (3887 aa) |
| | H0V2A9_CAVPO | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (106 aa) |
| | SCN4B | Sodium voltage-gated channel beta subunit 4. (184 aa) |
| | ATP1B3 | Sodium/potassium-transporting ATPase subunit beta-3; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known (By similarity); Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa) |
| | STIM2 | Stromal interaction molecule 2. (742 aa) |
| | TRPC1 | Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (810 aa) |
| | SCN2A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1965 aa) |
| | SCN1A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1997 aa) |
| | SLC8A1 | Sodium/calcium exchanger 1; Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to Ca(2+) transport during excitation-contraction coupling in muscle. In a first phase, voltage- gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum. SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels r [...] (970 aa) |
| | KCNK10 | Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (535 aa) |
| | ATP2A1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1001 aa) |
| | KCND3 | Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (654 aa) |
| | KCNK1 | Potassium channel subfamily K member 1; Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but also in kidney and in other tissues. Forms dimeric channels through which potassium ions pass in accordance with their electrochemical gradient. The channel is selective for K(+) ions at physiological potassium concentrations and at neutral pH, but becomes permeable to Na(+) at subphysiological K(+) levels and upon acidification of the extracellular medium. The homodimer has very low potassium [...] (336 aa) |
| | MAST1 | Microtubule associated serine/threonine kinase 1. (1555 aa) |
| | MAST4 | Microtubule associated serine/threonine kinase family member 4. (2436 aa) |
| | NPR2 | Guanylate cyclase. (1047 aa) |
| | ASPHD2 | Aspartate beta-hydroxylase domain containing 2. (334 aa) |
