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| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (481 aa) |
| | MAP3K20 | Mitogen-activated protein kinase kinase kinase 20. (711 aa) |
| | ENSCPOP00000030838 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (133 aa) |
| | FBXW11 | F-box and WD repeat domain containing 11. (530 aa) |
| | UBA3 | Ubiquitin like modifier activating enzyme 3. (380 aa) |
| | Ubc | Uncharacterized protein. (159 aa) |
| | PPP3R1 | Uncharacterized protein. (169 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (749 aa) |
| | NFAT5 | Nuclear factor of activated T cells 5. (1485 aa) |
| | MALT1 | MALT1 paracaspase. (780 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (916 aa) |
| | LOC106026468 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (174 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (271 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | Psma2 | Proteasome subunit alpha type. (234 aa) |
| | UBE2D2 | Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | PSME3 | Proteasome activator subunit 3. (254 aa) |
| | Psmd10 | ANK_REP_REGION domain-containing protein. (232 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (665 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | PSMB8 | Proteasome subunit beta. (273 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | PSMB6 | Proteasome subunit beta. (239 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1270 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (550 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (315 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1158 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (928 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (679 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa) |
| | NFKB2 | Nuclear factor kappa B subunit 2. (854 aa) |
| | SKP1 | S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...] (162 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (582 aa) |
| | Rps27a | Ubiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (389 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (967 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (531 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (518 aa) |
| | WDR92 | WD repeat domain 92. (357 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (739 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (350 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (322 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | PSME4 | Proteasome activator subunit 4. (1827 aa) |
| | PSMA8 | Proteasome subunit alpha type. (250 aa) |
| | UBE2V1 | Ubiquitin conjugating enzyme E2 V1. (145 aa) |
| | ENSCPOP00000027005 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (83 aa) |
| | CLEC7A | C-type lectin domain containing 7A. (204 aa) |
| | Psmd9 | PDZ domain-containing protein. (223 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | H0VWS1_CAVPO | ANK_REP_REGION domain-containing protein. (213 aa) |
| | PSMA7 | Proteasome endopeptidase complex. (248 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (458 aa) |
| | CASP10 | Caspase 10; Belongs to the peptidase C14A family. (474 aa) |
| | PSMA1 | Proteasome subunit alpha type. (270 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (263 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (377 aa) |
| | CARD9 | Caspase recruitment domain family member 9. (519 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (534 aa) |
| | BCL10 | BCL10 immune signaling adaptor. (234 aa) |
| | PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa) |
| | ENSCPOP00000031632 | Ubiquitin-like domain-containing protein. (141 aa) |
| | PSME2 | Proteasome activator subunit 2. (239 aa) |
| | ENSCPOP00000029251 | Uncharacterized protein; Belongs to the SKP1 family. (147 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | UBE2M | Ubiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (183 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | ENSCPOP00000029546 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (140 aa) |
| | UBB | Polyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa) |
| | RELB | RELB proto-oncogene, NF-kB subunit. (554 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1060 aa) |
| | ENSCPOP00000023362 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) |
| | PSME1 | Proteasome activator subunit 1. (249 aa) |
| | ENSCPOP00000023065 | ANK_REP_REGION domain-containing protein. (179 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | UBE2D1 | Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (139 aa) |
| | H0WDT2_CAVPO | Ubiquitin-like domain-containing protein. (127 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (507 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (416 aa) |
| | H0WAD6_CAVPO | Ubiquitin-like domain-containing protein. (111 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (504 aa) |
| | PSMB11 | Proteasome subunit beta. (297 aa) |
| | PSMB3 | Proteasome subunit beta. (207 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | MAP3K14 | Mitogen-activated protein kinase kinase kinase 14. (937 aa) |
