54 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	LZTFL1	Leucine zipper transcription factor like 1. (299 aa)
	RP2	Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. (350 aa)
	EXOC3	Exocyst complex component 3. (755 aa)
	RAB11A	Uncharacterized protein. (216 aa)
	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2. (988 aa)
	EXOC7	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (697 aa)
	Arf4	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (180 aa)
	CNGB3	Cyclic nucleotide gated channel subunit beta 3. (667 aa)
	PDE6D	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...] (149 aa)
	MKKS	McKusick-Kaufman syndrome. (575 aa)
	BBS5	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...] (341 aa)
	UNC119B	Unc-119 lipid binding chaperone B. (252 aa)
	ARL3	ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family. (189 aa)
	BBS10	Bardet-Biedl syndrome 10. (695 aa)
	ENSCPOP00000031438	annotation not available (62 aa)
	RAB8A	RAB8A, member RAS oncogene family. (207 aa)
	SSTR3	Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (432 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
	PKD2L2	Polycystin 2 like 2, transient receptor potential cation channel. (621 aa)
	CNGA4	Cyclic nucleotide gated channel subunit alpha 4. (574 aa)
	ENSCPOP00000026472	Uncharacterized protein. (286 aa)
	EXOC1	Exocyst complex component 1. (911 aa)
	TTC8	Tetratricopeptide repeat domain 8. (515 aa)
	BBS9	Bardet-Biedl syndrome 9. (887 aa)
	BBS7	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
	MYOT	Myotilin. (484 aa)
	ARL13B	ADP ribosylation factor like GTPase 13B. (382 aa)
	ARL6	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family. (186 aa)
	LOC100716676	TPR_REGION domain-containing protein. (567 aa)
	RHO	Rhodopsin. (348 aa)
	GBF1	Golgi brefeldin A resistant guanine nucleotide exchange factor 1. (1856 aa)
	EXOC6	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (804 aa)
	BBS2	Bardet-Biedl syndrome 2 protein homolog. (721 aa)
	EXOC2	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (924 aa)
	PKD1	Polycystin 1, transient receptor potential channel interacting. (4283 aa)
	H0VPN9_CAVPO	Uncharacterized protein. (402 aa)
	RAB11FIP3	RAB11 family interacting protein 3. (446 aa)
	PKD2	Polycystin 2, transient receptor potential cation channel. (839 aa)
	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1. (1147 aa)
	Nphp3	TPR_REGION domain-containing protein. (1281 aa)
	PKDREJ	Polycystin family receptor for egg jelly. (2029 aa)
	BBS12	Bardet-Biedl syndrome 12. (704 aa)
	EXOC8	Exocyst complex component 8. (716 aa)
	Bbs1	BBS1 domain-containing protein. (593 aa)
	CNGA2	Cyclic nucleotide gated channel subunit alpha 2. (663 aa)
	EXOC5	Exocyst complex component 5. (698 aa)
	MCHR1	Melanin concentrating hormone receptor 1. (355 aa)
	EXOC4	Exocyst complex component 4. (975 aa)
	ASAP3	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (901 aa)
	H0VQQ2_CAVPO	Cyclic nucleotide-binding domain-containing protein. (852 aa)
	INPP5E	Inositol polyphosphate-5-phosphatase E. (646 aa)
	EXOC6B	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (810 aa)
	EXOC3L1	Exocyst complex component 3 like 1. (773 aa)
	PKD2L1	Polycystin 2 like 1, transient receptor potential cation channel. (760 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL13B	ARL3	ENSCPOP00000002327	ENSCPOP00000030497	ADP ribosylation factor like GTPase 13B.	ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family.	0.842
ARL13B	ARL6	ENSCPOP00000002327	ENSCPOP00000004806	ADP ribosylation factor like GTPase 13B.	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	0.595
ARL13B	Arf4	ENSCPOP00000002327	ENSCPOP00000025910	ADP ribosylation factor like GTPase 13B.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.558
ARL13B	ENSCPOP00000031438	ENSCPOP00000002327	ENSCPOP00000031438	ADP ribosylation factor like GTPase 13B.	annotation not available	0.558
ARL13B	INPP5E	ENSCPOP00000002327	ENSCPOP00000008613	ADP ribosylation factor like GTPase 13B.	Inositol polyphosphate-5-phosphatase E.	0.877
ARL13B	LOC100716676	ENSCPOP00000002327	ENSCPOP00000004586	ADP ribosylation factor like GTPase 13B.	TPR_REGION domain-containing protein.	0.485
ARL13B	Nphp3	ENSCPOP00000002327	ENSCPOP00000014191	ADP ribosylation factor like GTPase 13B.	TPR_REGION domain-containing protein.	0.649
ARL13B	PDE6D	ENSCPOP00000002327	ENSCPOP00000026838	ADP ribosylation factor like GTPase 13B.	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]	0.874
ARL13B	PKD2	ENSCPOP00000002327	ENSCPOP00000013143	ADP ribosylation factor like GTPase 13B.	Polycystin 2, transient receptor potential cation channel.	0.560
ARL13B	RAB11A	ENSCPOP00000002327	ENSCPOP00000021498	ADP ribosylation factor like GTPase 13B.	Uncharacterized protein.	0.539
ARL13B	RAB8A	ENSCPOP00000002327	ENSCPOP00000031803	ADP ribosylation factor like GTPase 13B.	RAB8A, member RAS oncogene family.	0.431
ARL13B	SMO	ENSCPOP00000002327	ENSCPOP00000011817	ADP ribosylation factor like GTPase 13B.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.551
ARL13B	SSTR3	ENSCPOP00000002327	ENSCPOP00000032760	ADP ribosylation factor like GTPase 13B.	Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.480
ARL3	ARL13B	ENSCPOP00000030497	ENSCPOP00000002327	ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family.	ADP ribosylation factor like GTPase 13B.	0.842
ARL3	BBS2	ENSCPOP00000030497	ENSCPOP00000003348	ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family.	Bardet-Biedl syndrome 2 protein homolog.	0.463
ARL3	BBS5	ENSCPOP00000030497	ENSCPOP00000028238	ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family.	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	0.441
ARL3	BBS7	ENSCPOP00000030497	ENSCPOP00000001110	ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.622
ARL3	BBS9	ENSCPOP00000030497	ENSCPOP00000000840	ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family.	Bardet-Biedl syndrome 9.	0.532
ARL3	Bbs1	ENSCPOP00000030497	ENSCPOP00000020681	ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family.	BBS1 domain-containing protein.	0.729
ARL3	EXOC1	ENSCPOP00000030497	ENSCPOP00000026766	ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family.	Exocyst complex component 1.	0.410