16 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LZTFL1	Leucine zipper transcription factor like 1. (299 aa)
	ARL6	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family. (186 aa)
	LOC100716676	TPR_REGION domain-containing protein. (567 aa)
	SSTR3	Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (432 aa)
	TTC8	Tetratricopeptide repeat domain 8. (515 aa)
	BBS2	Bardet-Biedl syndrome 2 protein homolog. (721 aa)
	BBS12	Bardet-Biedl syndrome 12. (704 aa)
	Bbs1	BBS1 domain-containing protein. (593 aa)
	MKKS	McKusick-Kaufman syndrome. (575 aa)
	BBS5	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...] (341 aa)
	BBS10	Bardet-Biedl syndrome 10. (695 aa)
	H0VPN9_CAVPO	Uncharacterized protein. (402 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
	MCHR1	Melanin concentrating hormone receptor 1. (355 aa)
	BBS9	Bardet-Biedl syndrome 9. (887 aa)
	BBS7	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL6	BBS2	ENSCPOP00000004806	ENSCPOP00000003348	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Bardet-Biedl syndrome 2 protein homolog.	0.760
ARL6	BBS5	ENSCPOP00000004806	ENSCPOP00000028238	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	0.730
ARL6	BBS7	ENSCPOP00000004806	ENSCPOP00000001110	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.806
ARL6	BBS9	ENSCPOP00000004806	ENSCPOP00000000840	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Bardet-Biedl syndrome 9.	0.759
ARL6	Bbs1	ENSCPOP00000004806	ENSCPOP00000020681	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	BBS1 domain-containing protein.	0.827
ARL6	H0VPN9_CAVPO	ENSCPOP00000004806	ENSCPOP00000012474	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.617
ARL6	LOC100716676	ENSCPOP00000004806	ENSCPOP00000004586	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	TPR_REGION domain-containing protein.	0.759
ARL6	LZTFL1	ENSCPOP00000004806	ENSCPOP00000007283	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Leucine zipper transcription factor like 1.	0.594
ARL6	MCHR1	ENSCPOP00000004806	ENSCPOP00000010939	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Melanin concentrating hormone receptor 1.	0.440
ARL6	SMO	ENSCPOP00000004806	ENSCPOP00000011817	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.505
ARL6	SSTR3	ENSCPOP00000004806	ENSCPOP00000032760	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.405
ARL6	TTC8	ENSCPOP00000004806	ENSCPOP00000000619	ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.	Tetratricopeptide repeat domain 8.	0.797
BBS10	BBS12	ENSCPOP00000031137	ENSCPOP00000019320	Bardet-Biedl syndrome 10.	Bardet-Biedl syndrome 12.	0.969
BBS10	BBS2	ENSCPOP00000031137	ENSCPOP00000003348	Bardet-Biedl syndrome 10.	Bardet-Biedl syndrome 2 protein homolog.	0.686
BBS10	BBS5	ENSCPOP00000031137	ENSCPOP00000028238	Bardet-Biedl syndrome 10.	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	0.618
BBS10	BBS7	ENSCPOP00000031137	ENSCPOP00000001110	Bardet-Biedl syndrome 10.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.753
BBS10	BBS9	ENSCPOP00000031137	ENSCPOP00000000840	Bardet-Biedl syndrome 10.	Bardet-Biedl syndrome 9.	0.682
BBS10	Bbs1	ENSCPOP00000031137	ENSCPOP00000020681	Bardet-Biedl syndrome 10.	BBS1 domain-containing protein.	0.623
BBS10	LOC100716676	ENSCPOP00000031137	ENSCPOP00000004586	Bardet-Biedl syndrome 10.	TPR_REGION domain-containing protein.	0.624
BBS10	LZTFL1	ENSCPOP00000031137	ENSCPOP00000007283	Bardet-Biedl syndrome 10.	Leucine zipper transcription factor like 1.	0.599