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| | H0VW22_CAVPO | Protein kinase domain-containing protein. (399 aa) |
| | CDK5R1 | Cyclin-dependent kinase 5 activator. (307 aa) |
| | H0VYP1_CAVPO | Uncharacterized protein. (1054 aa) |
| | FOXP4 | Forkhead box P4. (677 aa) |
| | RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (401 aa) |
| | RFC5 | Replication factor C subunit 5. (340 aa) |
| | CHD3 | Chromodomain helicase DNA binding protein 3. (2003 aa) |
| | H0W160_CAVPO | Uncharacterized protein. (589 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (465 aa) |
| | AIRE | Autoimmune regulator. (540 aa) |
| | H0W426_CAVPO | Uncharacterized protein; Belongs to the protein kinase superfamily. (416 aa) |
| | POU4F3 | POU domain protein. (338 aa) |
| | MBD3 | Methyl-CpG binding domain protein 3. (290 aa) |
| | H0W6R4_CAVPO | WD_REPEATS_REGION domain-containing protein. (418 aa) |
| | SMYD2 | SET and MYND domain containing 2. (433 aa) |
| | HIPK4 | Homeodomain interacting protein kinase 4. (616 aa) |
| | H0WAD6_CAVPO | Ubiquitin-like domain-containing protein. (111 aa) |
| | DYRK3 | Dual specificity tyrosine phosphorylation regulated kinase 3. (587 aa) |
| | TP53BP2 | Tumor protein p53 binding protein 2. (1135 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (282 aa) |
| | CHD5 | Chromodomain helicase DNA binding protein 5. (1927 aa) |
| | ZNF385A | Zinc finger protein 385A. (386 aa) |
| | H0WDT2_CAVPO | Ubiquitin-like domain-containing protein. (127 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (420 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa) |
| | NUAK2 | NUAK family kinase 2. (638 aa) |
| | PIP4P1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (541 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (240 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1021 aa) |
| | ZNF385B | Zinc finger protein 385B. (477 aa) |
| | PIP4P2 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa) |
| | RAD1 | RAD1 checkpoint DNA exonuclease. (282 aa) |
| | TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (222 aa) |
| | TAF13 | TATA-box binding protein associated factor 13. (124 aa) |
| | NUAK1 | NUAK family kinase 1. (572 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (385 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (384 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (696 aa) |
| | ANKRD12 | Ankyrin repeat domain 12. (2046 aa) |
| | Taf1 | Transcription initiation factor TFIID subunit. (1836 aa) |
| | RHNO1 | RAD9-HUS1-RAD1 interacting nuclear orphan 1. (233 aa) |
| | ENSCPOP00000025455 | Protein kinase domain-containing protein. (360 aa) |
| | TAF11 | TATA-box binding protein associated factor 11. (210 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1471 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (166 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (435 aa) |
| | Ing1 | Inhibitor of growth protein. (266 aa) |
| | RBBP7 | RB binding protein 7, chromatin remodeling factor. (469 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | DAXX | Death domain associated protein. (756 aa) |
| | ENSCPOP00000026334 | WD_REPEATS_REGION domain-containing protein. (385 aa) |
| | AURKB | Aurora kinase B; Belongs to the protein kinase superfamily. (339 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | TAF4 | TATA-box binding protein associated factor 4. (637 aa) |
| | TOPBP1 | DNA topoisomerase II binding protein 1. (1392 aa) |
| | PRR5 | Proline rich 5. (358 aa) |
| | Ly6g5b | Uncharacterized protein. (195 aa) |
| | MEAF6 | MYST/Esa1 associated factor 6. (171 aa) |
| | USP2 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (611 aa) |
| | MAPKAP1 | MAPK associated protein 1. (522 aa) |
| | HIPK1 | Homeodomain interacting protein kinase 1. (1235 aa) |
| | L3MBTL3 | L3MBTL histone methyl-lysine binding protein 3. (779 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (641 aa) |
| | RFFL | Ring finger and FYVE like domain containing E3 ubiquitin protein ligase. (398 aa) |
| | ENSCPOP00000029129 | Protein kinase domain-containing protein. (254 aa) |
| | SGK1 | Non-specific serine/threonine protein kinase. (526 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) |
| | GATAD2A | GATA zinc finger domain containing 2A. (640 aa) |
| | TAF7 | TATA-box binding protein associated factor 7. (349 aa) |
| | PWWP2A | PWWP domain containing 2A. (722 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (423 aa) |
| | RMI2 | RecQ mediated genome instability 2. (147 aa) |
| | ENSCPOP00000029900 | Uncharacterized protein. (195 aa) |
| | UBB | Polyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa) |
| | ENSCPOP00000030085 | AMPKBI domain-containing protein. (256 aa) |
| | PPP1R13B | Protein phosphatase 1 regulatory subunit 13B. (1126 aa) |
| | CCNG1 | Cyclin G1; Belongs to the cyclin family. (295 aa) |
| | KMT5A | Lysine methyltransferase 5A. (295 aa) |
| | ENSCPOP00000030815 | CAF1C_H4-bd domain-containing protein. (54 aa) |
| | ENSCPOP00000030888 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (238 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | ENSCPOP00000031632 | Ubiquitin-like domain-containing protein. (141 aa) |
| | TBP | TATA-box binding protein. (321 aa) |
| | Ubc | Uncharacterized protein. (159 aa) |
| | TAF9 | Uncharacterized protein. (263 aa) |
| | ING5 | Inhibitor of growth protein. (213 aa) |
| | CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa) |
| | TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1027 aa) |
| | NOC2L | NOC2 like nucleolar associated transcriptional repressor. (799 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (589 aa) |
| | PPP1R13L | Protein phosphatase 1 regulatory subunit 13 like. (781 aa) |
| | RECQL4 | RecQ like helicase 4. (1226 aa) |
| | AKT3 | AKT serine/threonine kinase 3. (470 aa) |
| | BRD7 | Bromodomain containing 7. (642 aa) |
| | Rbbp4 | WD_REPEATS_REGION domain-containing protein. (425 aa) |
| | SETD9 | SET domain containing 9. (299 aa) |
| | EHMT2 | Euchromatic histone lysine methyltransferase 2. (1188 aa) |
| | MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (706 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | MTA2 | Metastasis associated 1 family member 2. (668 aa) |
| | TAF2 | TATA-box binding protein associated factor 2. (1109 aa) |
| | PRDM1 | PR/SET domain 1. (813 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa) |
| | POU4F2 | POU domain protein. (408 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (751 aa) |
| | Brca1 | Uncharacterized protein. (79 aa) |
| | AURKC | Aurora kinase C; Belongs to the protein kinase superfamily. (257 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (177 aa) |
| | RFC2 | Replication factor C subunit 2. (352 aa) |
| | ING2 | Inhibitor of growth protein. (280 aa) |
| | TBPL1 | TATA-box binding protein like 1. (179 aa) |
| | KAT6A | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2011 aa) |
| | BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (971 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | BARD1 | BRCA1 associated RING domain 1. (662 aa) |
| | RFC4 | Replication factor C subunit 4. (363 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3031 aa) |
| | CSNK2B | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (244 aa) |
| | TDRD3 | Tudor domain containing 3. (692 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (429 aa) |
| | GATAD2B | GATA zinc finger domain containing 2B. (593 aa) |
| | LOC101788648 | Uncharacterized protein. (485 aa) |
| | BRPF3 | Bromodomain and PHD finger containing 3. (1208 aa) |
| | DYRK4 | Dual specificity tyrosine phosphorylation regulated kinase 4; Belongs to the protein kinase superfamily. (484 aa) |
| | RMI1 | RecQ mediated genome instability 1. (617 aa) |
| | EXD2 | Exonuclease 3'-5' domain containing 2. (619 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) |
| | MAPKAPK5 | MAPK activated protein kinase 5. (474 aa) |
| | Plk5 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (460 aa) |
| | TAF12 | TATA-box binding protein associated factor 12. (213 aa) |
| | TPX2 | TPX2 microtubule nucleation factor. (747 aa) |
| | TTC5 | Tetratricopeptide repeat domain 5. (445 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) |
| | H0VDI1_CAVPO | Uncharacterized protein. (809 aa) |
| | BRPF1 | Bromodomain and PHD finger containing 1. (1213 aa) |
| | RPA2 | Replication protein A2. (270 aa) |
| | RFC3 | Replication factor C subunit 3. (220 aa) |
| | LOC100734047 | Uncharacterized protein. (567 aa) |
| | Chd4 | Uncharacterized protein. (1900 aa) |
| | CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (349 aa) |
| | JMY | Junction mediating and regulatory protein, p53 cofactor. (908 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (485 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (900 aa) |
| | BANP | BTG3 associated nuclear protein. (435 aa) |
| | PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (398 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1189 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2539 aa) |
| | Ehmt1 | Uncharacterized protein. (1249 aa) |
| | Aurka | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (384 aa) |
| | ZNF385C | Zinc finger protein 385C. (410 aa) |
| | CHEK2 | Checkpoint kinase 2. (546 aa) |
| | Rps27a | Ubiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa) |
| | Csnk2a1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) |
| | TP53RK | TP53 regulating kinase. (246 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (362 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (559 aa) |
| | EP300 | E1A binding protein p300. (2425 aa) |
| | Cdk1 | Protein kinase domain-containing protein. (240 aa) |
| | BRD1 | Bromodomain containing 1. (1189 aa) |
| | TAF5 | TATA-box binding protein associated factor 5. (762 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (308 aa) |
| | TAF6 | TATA-box binding protein associated factor 6. (678 aa) |
| | TXNDC11 | Thioredoxin domain containing 11. (948 aa) |
| | SLF1 | SMC5-SMC6 complex localization factor 1. (1061 aa) |
| | RNF34 | Ring finger protein 34. (376 aa) |
| | BRD9 | Bromodomain containing 9. (597 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (550 aa) |
| | USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1101 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (329 aa) |
| | WRN | WRN RecQ like helicase. (1462 aa) |
| | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit. (887 aa) |
| | Rad50 | Zinc-hook domain-containing protein. (1275 aa) |
| | PLK3 | Serine/threonine-protein kinase PLK. (646 aa) |
| | TAF9B | TATA-box binding protein associated factor 9b. (251 aa) |
| | HIPK3 | Homeodomain interacting protein kinase 3. (1217 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (326 aa) |
| | PHF20 | PHD finger protein 20. (1007 aa) |
| | TAF3 | TATA-box binding protein associated factor 3. (928 aa) |
| | BLM | BLM RecQ like helicase. (1405 aa) |
| | MEIOB | Meiosis specific with OB-fold. (471 aa) |
| | TAF4B | TATA-box binding protein associated factor 4b. (831 aa) |
| | PML | Promyelocytic leukemia. (849 aa) |
| | RAD17 | RAD17 checkpoint clamp loader component. (696 aa) |
| | DYRK2 | Dual specificity tyrosine phosphorylation regulated kinase 2. (601 aa) |
| | Taf7l | TAFII55_N domain-containing protein. (342 aa) |
| | SSRP1 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa) |
| | ATRIP | ATR interacting protein. (792 aa) |
| | EXO1 | Exonuclease 1. (839 aa) |
| | Prkab1 | AMPKBI domain-containing protein. (270 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (567 aa) |
| | PIP4K2C | Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (419 aa) |
| | Chek1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (439 aa) |
