STRINGSTRING
PSMD8 PSMD8 PSMD7 PSMD7 PSMC5 PSMC5 PSME4 PSME4 UBA52 UBA52 PSMB8 PSMB8 PSMB1 PSMB1 PSMB6 PSMB6 PSMB9 PSMB9 SYNGAP1 SYNGAP1 RASAL3 RASAL3 PSMD13 PSMD13 PSMC4 PSMC4 CUL3 CUL3 Rps27a Rps27a NF1 NF1 PSMA8 PSMA8 PSMA5 PSMA5 PSMF1 PSMF1 RASA2 RASA2 PSMB5 PSMB5 PSMA7 PSMA7 Psmd10 Psmd10 PSMD3 PSMD3 PSMB4 PSMB4 PSMA1 PSMA1 PSMC2 PSMC2 H0VWS1_CAVPO H0VWS1_CAVPO RASAL1 RASAL1 Psmd9 Psmd9 PSMA4 PSMA4 PSMB3 PSMB3 PSMB11 PSMB11 PSMD5 PSMD5 H0WAD6_CAVPO H0WAD6_CAVPO PSMB10 PSMB10 H0WDT2_CAVPO H0WDT2_CAVPO PSMD1 PSMD1 PSMA3 PSMA3 ENSCPOP00000023065 ENSCPOP00000023065 PSME1 PSME1 PSMC3 PSMC3 PSMD2 PSMD2 RBX1 RBX1 PSMD14 PSMD14 PSMD4 PSMD4 DAB2IP DAB2IP RASAL2 RASAL2 PSMD12 PSMD12 PSMB2 PSMB2 PSMA6 PSMA6 SPRED2 SPRED2 SPRED3 SPRED3 UBB UBB PSMC1 PSMC1 Rasa4b Rasa4b ENSCPOP00000031632 ENSCPOP00000031632 CSDE1 CSDE1 PSME2 PSME2 Ubc Ubc SPRED1 SPRED1 Psma2 Psma2 PSME3 PSME3 HRAS HRAS PSMD6 PSMD6 RASA3 RASA3 PSMB7 PSMB7 RASA1 RASA1 LOC100730225 LOC100730225 PSMC6 PSMC6 PSMD11 PSMD11 NRAS NRAS KRAS KRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSME4Proteasome activator subunit 4. (1827 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
PSMB8Proteasome subunit beta. (273 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSMB9Proteasome subunit beta. (219 aa)
SYNGAP1Synaptic Ras GTPase activating protein 1. (1284 aa)
RASAL3RAS protein activator like 3. (1024 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (315 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
CUL3Cullin 3; Belongs to the cullin family. (765 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
NF1Neurofibromin 1. (2750 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
RASA2RAS p21 protein activator 2. (850 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMA7Proteasome endopeptidase complex. (248 aa)
Psmd10ANK_REP_REGION domain-containing protein. (232 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (263 aa)
PSMA1Proteasome subunit alpha type. (270 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (458 aa)
H0VWS1_CAVPOANK_REP_REGION domain-containing protein. (213 aa)
RASAL1RAS protein activator like 1. (801 aa)
Psmd9PDZ domain-containing protein. (223 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMB3Proteasome subunit beta. (207 aa)
PSMB11Proteasome subunit beta. (297 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
PSMB10Proteasome subunit beta. (273 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
ENSCPOP00000023065ANK_REP_REGION domain-containing protein. (179 aa)
PSME1Proteasome activator subunit 1. (249 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
RBX1Ring-box 1. (108 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (377 aa)
DAB2IPDAB2 interacting protein. (1193 aa)
RASAL2RAS protein activator like 2. (1280 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
SPRED2Sprouty related EVH1 domain containing 2. (413 aa)
SPRED3Sprouty related EVH1 domain containing 3. (408 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
Rasa4bUncharacterized protein. (802 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
CSDE1Cold shock domain-containing protein E1; RNA-binding protein. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain (By similarity). (779 aa)
PSME2Proteasome activator subunit 2. (239 aa)
UbcUncharacterized protein. (159 aa)
SPRED1Sprouty related EVH1 domain containing 1. (438 aa)
Psma2Proteasome subunit alpha type. (234 aa)
PSME3Proteasome activator subunit 3. (254 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
RASA3RAS p21 protein activator 3. (833 aa)
PSMB7Proteasome subunit beta. (277 aa)
RASA1RAS p21 protein activator 1. (1024 aa)
LOC100730225BTB domain-containing protein. (659 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
NRASGTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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