STRINGSTRING
PPP2CB PPP2CB HRAS HRAS STYX STYX DUSP8 DUSP8 MOB2 MOB2 Ubc Ubc CSDE1 CSDE1 BRAF BRAF ENSCPOP00000031632 ENSCPOP00000031632 UBB UBB DUSP16 DUSP16 SSH1 SSH1 DUSP1 DUSP1 DUSP4 DUSP4 SSH2 SSH2 PPP2R5E PPP2R5E DUSP22 DUSP22 DUSP19 DUSP19 PPP2R1B PPP2R1B YWHAB YWHAB PPP2CA PPP2CA DUSP9 DUSP9 PPP2R5C PPP2R5C FNBP4 FNBP4 UBA52 UBA52 KSR1 KSR1 RAF1 RAF1 DUSP12 DUSP12 PPP4R1 PPP4R1 PTPN7 PTPN7 MAP2K1 MAP2K1 MAPK3 MAPK3 DUSP6 DUSP6 PPP2R5A PPP2R5A PPP5C PPP5C Pebp1 Pebp1 BRAP BRAP PEBP4 PEBP4 H0WDT2_CAVPO H0WDT2_CAVPO H0WAD6_CAVPO H0WAD6_CAVPO DUSP28 DUSP28 H0W160_CAVPO H0W160_CAVPO DUSP5 DUSP5 DUSP2 DUSP2 PPP2R5B PPP2R5B MAP2K2 MAP2K2 RELCH RELCH MAPK12 MAPK12 PPP4R4 PPP4R4 DUSP10 DUSP10 ARAF ARAF MAPK1 MAPK1 PAQR3 PAQR3 PPP2R5D PPP2R5D KRAS KRAS NRAS NRAS PTPN3 PTPN3 Dusp15 Dusp15 SSH3 SSH3 LOC100734047 LOC100734047 DUSP7 DUSP7 Rps27a Rps27a PTPRR PTPRR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP2CBSerine/threonine-protein phosphatase. (308 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
STYXSerine/threonine/tyrosine interacting protein. (223 aa)
DUSP8Dual specificity phosphatase 8. (609 aa)
MOB2MOB kinase activator 2. (265 aa)
UbcUncharacterized protein. (159 aa)
CSDE1Cold shock domain-containing protein E1; RNA-binding protein. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain (By similarity). (779 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (738 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
DUSP16Dual specificity phosphatase 16. (662 aa)
SSH1Slingshot protein phosphatase 1. (1053 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (368 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (393 aa)
SSH2Slingshot protein phosphatase 2. (1444 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
DUSP22Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (172 aa)
DUSP19Dual specificity phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (229 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (696 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
DUSP9Dual specificity phosphatase 9. (265 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (589 aa)
FNBP4Formin binding protein 4. (1044 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
KSR1Kinase suppressor of ras 1. (879 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
DUSP12Dual specificity phosphatase 12. (338 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (942 aa)
PTPN7Protein tyrosine phosphatase non-receptor type 7. (360 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (487 aa)
PPP5CSerine/threonine-protein phosphatase. (533 aa)
Pebp1Uncharacterized protein. (187 aa)
BRAPBRCA1 associated protein. (592 aa)
PEBP4Phosphatidylethanolamine binding protein 4. (209 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
DUSP28Dual specificity phosphatase 28. (178 aa)
H0W160_CAVPOUncharacterized protein. (589 aa)
DUSP5Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (375 aa)
DUSP2Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (363 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1097 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (832 aa)
DUSP10Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (608 aa)
MAPK1Mitogen-activated protein kinase. (325 aa)
PAQR3Progestin and adipoQ receptor family member 3. (310 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (594 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
NRASGTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa)
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (912 aa)
Dusp15Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (236 aa)
SSH3Slingshot protein phosphatase 3. (652 aa)
LOC100734047Uncharacterized protein. (567 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
PTPRRProtein tyrosine phosphatase receptor type R. (657 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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