STRINGSTRING
PSMF1 PSMF1 Prkaca Prkaca HSPB1 HSPB1 PSME3 PSME3 Psma2 Psma2 Ubc Ubc PSME2 PSME2 ENSCPOP00000031632 ENSCPOP00000031632 CDC42 CDC42 PSMC1 PSMC1 DUSP23 DUSP23 CDC14A CDC14A ENSCPOP00000030888 ENSCPOP00000030888 UBB UBB SEPTIN7 SEPTIN7 PSMA6 PSMA6 PSMB2 PSMB2 PSMD12 PSMD12 ENSCPOP00000029129 ENSCPOP00000029129 PSMD4 PSMD4 PSMD14 PSMD14 DNAJB1 DNAJB1 CDC42EP3 CDC42EP3 PRKACB PRKACB CDC42EP2 CDC42EP2 PSMD2 PSMD2 MAPK6 MAPK6 PSMC3 PSMC3 BRSK2 BRSK2 PAK3 PAK3 PSME1 PSME1 ENSCPOP00000023065 ENSCPOP00000023065 PAK2 PAK2 XPO1 XPO1 PSMA3 PSMA3 RAC1 RAC1 PSMD1 PSMD1 ETV1 ETV1 H0WDT2_CAVPO H0WDT2_CAVPO RSPH6A RSPH6A PSMB10 PSMB10 H0WAD6_CAVPO H0WAD6_CAVPO RAG1 RAG1 PSMD5 PSMD5 PSMB11 PSMB11 PSMB3 PSMB3 RAG2 RAG2 PSMA4 PSMA4 Foxo3 Foxo3 Psmd9 Psmd9 H0VWS1_CAVPO H0VWS1_CAVPO CCND3 CCND3 PSMC2 PSMC2 IGF2BP1 IGF2BP1 PSMA1 PSMA1 PSMB4 PSMB4 PSMD3 PSMD3 Psmd10 Psmd10 DNAJB5 DNAJB5 MOV10 MOV10 PSMA7 PSMA7 PSMB5 PSMB5 PSMA5 PSMA5 KALRN KALRN PSMA8 PSMA8 PSME4 PSME4 PSMC5 PSMC5 PSMD7 PSMD7 PSMD8 PSMD8 DNAJB13 DNAJB13 MAPK4 MAPK4 DNAJB4 DNAJB4 PSMD11 PSMD11 PSMC6 PSMC6 MAPKAPK5 MAPKAPK5 BRSK1 BRSK1 H0VCZ7_CAVPO H0VCZ7_CAVPO NCOA3 NCOA3 PSMB7 PSMB7 PSMD6 PSMD6 CDC14C CDC14C Rps27a Rps27a Cdk1 Cdk1 TMEM232 TMEM232 CDKN3 CDKN3 PSMC4 PSMC4 PSMD13 PSMD13 ETV4 ETV4 PSMB9 PSMB9 PSMB6 PSMB6 PSMB1 PSMB1 PSMB8 PSMB8 RSPH4A RSPH4A UBA52 UBA52 PAK1 PAK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PrkacaUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (200 aa)
PSME3Proteasome activator subunit 3. (254 aa)
Psma2Proteasome subunit alpha type. (234 aa)
UbcUncharacterized protein. (159 aa)
PSME2Proteasome activator subunit 2. (239 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
CDC42Cell division cycle 42. (191 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
DUSP23Dual specificity phosphatase 23. (150 aa)
CDC14ACell division cycle 14A. (596 aa)
ENSCPOP00000030888Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (238 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
SEPTIN7Septin 7; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (438 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
ENSCPOP00000029129Protein kinase domain-containing protein. (254 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (377 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
DNAJB1DnaJ heat shock protein family (Hsp40) member B1. (339 aa)
CDC42EP3CDC42 effector protein 3. (254 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
CDC42EP2Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family. (210 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
MAPK6Mitogen-activated protein kinase 6. (716 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
BRSK2BR serine/threonine kinase 2. (718 aa)
PAK3Non-specific serine/threonine protein kinase. (559 aa)
PSME1Proteasome activator subunit 1. (249 aa)
ENSCPOP00000023065ANK_REP_REGION domain-containing protein. (179 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
XPO1Exportin 1. (1062 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (211 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
ETV1ETS variant 1. (454 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
RSPH6ARadial spoke head 6 homolog A. (452 aa)
PSMB10Proteasome subunit beta. (273 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PSMB11Proteasome subunit beta. (297 aa)
PSMB3Proteasome subunit beta. (207 aa)
RAG2Recombination activating 2. (527 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
Foxo3Forkhead box O3. (660 aa)
Psmd9PDZ domain-containing protein. (223 aa)
H0VWS1_CAVPOANK_REP_REGION domain-containing protein. (213 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (211 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (458 aa)
IGF2BP1Insulin like growth factor 2 mRNA binding protein 1. (547 aa)
PSMA1Proteasome subunit alpha type. (270 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (263 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
Psmd10ANK_REP_REGION domain-containing protein. (232 aa)
DNAJB5DnaJ heat shock protein family (Hsp40) member B5. (382 aa)
MOV10Mov10 RISC complex RNA helicase. (1063 aa)
PSMA7Proteasome endopeptidase complex. (248 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
KALRNKalirin RhoGEF kinase. (2964 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PSME4Proteasome activator subunit 4. (1827 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
DNAJB13DnaJ heat shock protein family (Hsp40) member B13. (316 aa)
MAPK4Mitogen-activated protein kinase 4. (583 aa)
DNAJB4DnaJ heat shock protein family (Hsp40) member B4. (337 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
MAPKAPK5MAPK activated protein kinase 5. (474 aa)
BRSK1BR serine/threonine kinase 1. (763 aa)
H0VCZ7_CAVPOFork-head domain-containing protein. (548 aa)
NCOA3Nuclear receptor coactivator. (1418 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
CDC14CCell division cycle 14C. (453 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
Cdk1Protein kinase domain-containing protein. (240 aa)
TMEM232Transmembrane protein 232. (607 aa)
CDKN3Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (211 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (315 aa)
ETV4ETS variant 4. (464 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMB8Proteasome subunit beta. (273 aa)
RSPH4ARadial spoke head component 4A. (509 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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