STRINGSTRING
PRKN PRKN SPATA5L1 SPATA5L1 Atxn3 Atxn3 H0WAD6_CAVPO H0WAD6_CAVPO H0WDT2_CAVPO H0WDT2_CAVPO ENSCPOP00000021625 ENSCPOP00000021625 ASPDH ASPDH RAD23B RAD23B JOSD2 JOSD2 RAD23A RAD23A JOSD1 JOSD1 UBB UBB ENSCPOP00000031632 ENSCPOP00000031632 Ubc Ubc VCP VCP UBA52 UBA52 SPATA5 SPATA5 Rps27a Rps27a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (443 aa)
SPATA5L1Spermatogenesis associated 5 like 1; Belongs to the AAA ATPase family. (634 aa)
Atxn3Josephin domain-containing protein. (351 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
ENSCPOP00000021625Josephin domain-containing protein. (177 aa)
ASPDHAspartate dehydrogenase domain containing. (284 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (409 aa)
JOSD2Josephin domain containing 2. (188 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (362 aa)
JOSD1Josephin domain containing 1. (202 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
UbcUncharacterized protein. (159 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
SPATA5Spermatogenesis associated 5. (884 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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