STRINGSTRING
VWA5B1 VWA5B1 ACTL6A ACTL6A Ubc Ubc ENSCPOP00000031632 ENSCPOP00000031632 COPS7B COPS7B CETN3 CETN3 UBB UBB WBP1 WBP1 RAD23A RAD23A DDB1 DDB1 INO80C INO80C CUL4B CUL4B RBX1 RBX1 RAD23B RAD23B ENSCPOP00000024428 ENSCPOP00000024428 COPS8 COPS8 ENSCPOP00000022087 ENSCPOP00000022087 H0WDT2_CAVPO H0WDT2_CAVPO VWA5B2 VWA5B2 H0WAD6_CAVPO H0WAD6_CAVPO H0W9J0_CAVPO H0W9J0_CAVPO PARP2 PARP2 COPS4 COPS4 Yy1 Yy1 COPS6 COPS6 Parp1 Parp1 PARP3 PARP3 DDB2 DDB2 Ino80b Ino80b Cetn2 Cetn2 INO80E INO80E COPS5 COPS5 ACTR5 ACTR5 TFPT TFPT INO80 INO80 MCRS1 MCRS1 H0VI45_CAVPO H0VI45_CAVPO RUVBL1 RUVBL1 CUL4A CUL4A ACTR8 ACTR8 XPC XPC Rps27a Rps27a COPS3 COPS3 VWA5A VWA5A COPS2 COPS2 RPAP3 RPAP3 WDR76 WDR76 GPS1 GPS1 NFRKB NFRKB UBA52 UBA52 COPS7A COPS7A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VWA5B1Von Willebrand factor A domain containing 5B1. (1203 aa)
ACTL6AActin like 6A; Belongs to the actin family. (429 aa)
UbcUncharacterized protein. (159 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
COPS7BCOP9 signalosome subunit 7B. (264 aa)
CETN3Centrin 3. (163 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
WBP1WW domain binding protein 1. (303 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (362 aa)
DDB1Damage specific DNA binding protein 1. (1140 aa)
INO80CINO80 complex subunit C. (192 aa)
CUL4BCullin 4B; Belongs to the cullin family. (936 aa)
RBX1Ring-box 1. (108 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (409 aa)
ENSCPOP00000024428PARP-type domain-containing protein. (104 aa)
COPS8COP9 signalosome subunit 8. (209 aa)
ENSCPOP00000022087Uncharacterized protein. (161 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
VWA5B2Von Willebrand factor A domain containing 5B2. (1204 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
H0W9J0_CAVPOUncharacterized protein. (147 aa)
PARP2Poly [ADP-ribose] polymerase. (536 aa)
COPS4COP9 signalosome subunit 4. (371 aa)
Yy1Uncharacterized protein. (195 aa)
COPS6COP9 signalosome subunit 6. (325 aa)
Parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1011 aa)
PARP3Poly [ADP-ribose] polymerase. (533 aa)
DDB2Damage specific DNA binding protein 2. (289 aa)
Ino80bPAPA-1 domain-containing protein. (373 aa)
Cetn2Uncharacterized protein. (172 aa)
INO80EINO80 complex subunit E. (244 aa)
COPS5COP9 signalosome subunit 5. (334 aa)
ACTR5Actin related protein 5; Belongs to the actin family. (602 aa)
TFPTTCF3 fusion partner. (257 aa)
INO80INO80 complex ATPase subunit. (1558 aa)
MCRS1Microspherule protein 1. (462 aa)
H0VI45_CAVPOzf-C3Hc3H domain-containing protein. (414 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
CUL4ACullin 4A; Belongs to the cullin family. (759 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (923 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
COPS3COP9 signalosome subunit 3. (423 aa)
VWA5AVon Willebrand factor A domain containing 5A. (798 aa)
COPS2COP9 signalosome subunit 2. (443 aa)
RPAP3RNA polymerase II associated protein 3. (665 aa)
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (623 aa)
GPS1G protein pathway suppressor 1. (487 aa)
NFRKBNuclear factor related to kappaB binding protein. (1298 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
COPS7ACOP9 signalosome subunit 7A. (275 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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