STRINGSTRING
Rbbp4 Rbbp4 BRD7 BRD7 AKT3 AKT3 PIP4K2C PIP4K2C FOXP4 FOXP4 CHD3 CHD3 AIRE AIRE MBD3 MBD3 H0W6R4_CAVPO H0W6R4_CAVPO CHD5 CHD5 PIP4P1 PIP4P1 MAP2K6 MAP2K6 PIP4P2 PIP4P2 PIN1 PIN1 Ing1 Ing1 RBBP7 RBBP7 AKT1 AKT1 ENSCPOP00000026334 ENSCPOP00000026334 MEAF6 MEAF6 GATAD2A GATAD2A TP53 TP53 ENSCPOP00000030815 ENSCPOP00000030815 AKT2 AKT2 ING5 ING5 BRD9 BRD9 BRD1 BRD1 EP300 EP300 PIP4K2B PIP4K2B PIP4K2A PIP4K2A HDAC1 HDAC1 Chd4 Chd4 BRPF1 BRPF1 BRPF3 BRPF3 GATAD2B GATAD2B PML PML KAT6A KAT6A ING2 ING2 MTA2 MTA2 HDAC2 HDAC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Rbbp4WD_REPEATS_REGION domain-containing protein. (425 aa)
BRD7Bromodomain containing 7. (642 aa)
AKT3AKT serine/threonine kinase 3. (470 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (419 aa)
FOXP4Forkhead box P4. (677 aa)
CHD3Chromodomain helicase DNA binding protein 3. (2003 aa)
AIREAutoimmune regulator. (540 aa)
MBD3Methyl-CpG binding domain protein 3. (290 aa)
H0W6R4_CAVPOWD_REPEATS_REGION domain-containing protein. (418 aa)
CHD5Chromodomain helicase DNA binding protein 5. (1927 aa)
PIP4P1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
PIP4P2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (166 aa)
Ing1Inhibitor of growth protein. (266 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (469 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ENSCPOP00000026334WD_REPEATS_REGION domain-containing protein. (385 aa)
MEAF6MYST/Esa1 associated factor 6. (171 aa)
GATAD2AGATA zinc finger domain containing 2A. (640 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (423 aa)
ENSCPOP00000030815CAF1C_H4-bd domain-containing protein. (54 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ING5Inhibitor of growth protein. (213 aa)
BRD9Bromodomain containing 9. (597 aa)
BRD1Bromodomain containing 1. (1189 aa)
EP300E1A binding protein p300. (2425 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (362 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (398 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
Chd4Uncharacterized protein. (1900 aa)
BRPF1Bromodomain and PHD finger containing 1. (1213 aa)
BRPF3Bromodomain and PHD finger containing 3. (1208 aa)
GATAD2BGATA zinc finger domain containing 2B. (593 aa)
PMLPromyelocytic leukemia. (849 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2011 aa)
ING2Inhibitor of growth protein. (280 aa)
MTA2Metastasis associated 1 family member 2. (668 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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