17 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Pola2	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa)
	RFC5	Replication factor C subunit 5. (340 aa)
	POLD2	DNA polymerase delta 2, accessory subunit. (469 aa)
	POLD1	DNA polymerase. (1134 aa)
	RFC2	Replication factor C subunit 2. (352 aa)
	ATAD5	ATPase family AAA domain containing 5. (1831 aa)
	RCBTB1	RCC1 and BTB domain containing protein 1. (531 aa)
	RCBTB2	RCC1 and BTB domain containing protein 2. (551 aa)
	Pold4	Uncharacterized protein. (107 aa)
	RFC4	Replication factor C subunit 4. (363 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	RFC3	Replication factor C subunit 3. (220 aa)
	Pold3	Uncharacterized protein. (466 aa)
	RFC1	Replication factor C subunit 1. (1153 aa)
	PRIM2	DNA primase subunit 2. (432 aa)
	POLA1	DNA polymerase. (1467 aa)
	Prim1	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (419 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	PCNA	ENSCPOP00000010706	ENSCPOP00000008297	ATPase family AAA domain containing 5.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.990
ATAD5	POLA1	ENSCPOP00000010706	ENSCPOP00000001937	ATPase family AAA domain containing 5.	DNA polymerase.	0.896
ATAD5	POLD1	ENSCPOP00000010706	ENSCPOP00000021510	ATPase family AAA domain containing 5.	DNA polymerase.	0.862
ATAD5	POLD2	ENSCPOP00000010706	ENSCPOP00000018386	ATPase family AAA domain containing 5.	DNA polymerase delta 2, accessory subunit.	0.728
ATAD5	PRIM2	ENSCPOP00000010706	ENSCPOP00000003531	ATPase family AAA domain containing 5.	DNA primase subunit 2.	0.870
ATAD5	Pola2	ENSCPOP00000010706	ENSCPOP00000001676	ATPase family AAA domain containing 5.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.902
ATAD5	Pold4	ENSCPOP00000010706	ENSCPOP00000022371	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.519
ATAD5	Prim1	ENSCPOP00000010706	ENSCPOP00000014464	ATPase family AAA domain containing 5.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.845
ATAD5	RFC1	ENSCPOP00000010706	ENSCPOP00000003832	ATPase family AAA domain containing 5.	Replication factor C subunit 1.	0.760
ATAD5	RFC2	ENSCPOP00000010706	ENSCPOP00000011113	ATPase family AAA domain containing 5.	Replication factor C subunit 2.	0.991
ATAD5	RFC3	ENSCPOP00000010706	ENSCPOP00000007845	ATPase family AAA domain containing 5.	Replication factor C subunit 3.	0.997
ATAD5	RFC4	ENSCPOP00000010706	ENSCPOP00000010061	ATPase family AAA domain containing 5.	Replication factor C subunit 4.	0.998
ATAD5	RFC5	ENSCPOP00000010706	ENSCPOP00000016590	ATPase family AAA domain containing 5.	Replication factor C subunit 5.	0.996
PCNA	ATAD5	ENSCPOP00000008297	ENSCPOP00000010706	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	ATPase family AAA domain containing 5.	0.990
PCNA	POLA1	ENSCPOP00000008297	ENSCPOP00000001937	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase.	0.992
PCNA	POLD1	ENSCPOP00000008297	ENSCPOP00000021510	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase.	0.999
PCNA	POLD2	ENSCPOP00000008297	ENSCPOP00000018386	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase delta 2, accessory subunit.	0.999
PCNA	PRIM2	ENSCPOP00000008297	ENSCPOP00000003531	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA primase subunit 2.	0.982
PCNA	Pola2	ENSCPOP00000008297	ENSCPOP00000001676	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.968
PCNA	Pold3	ENSCPOP00000008297	ENSCPOP00000006376	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.996