STRINGSTRING
H0W9U2_CAVPO H0W9U2_CAVPO Ccnd2 Ccnd2 H0W160_CAVPO H0W160_CAVPO CUL1 CUL1 CDKN2A CDKN2A CCND3 CCND3 PPP2R2A PPP2R2A RELCH RELCH CDK7 CDK7 JAK2 JAK2 MNAT1 MNAT1 PPP4R4 PPP4R4 TFDP1 TFDP1 Ccne2 Ccne2 Skp2 Skp2 FNDC3B FNDC3B LYN LYN E2F4 E2F4 CDK2 CDK2 E2F2 E2F2 RB1 RB1 LOC100734047 LOC100734047 PTK6 PTK6 RBL2 RBL2 Rps27a Rps27a PPP2CB PPP2CB SKP1 SKP1 CCNE1 CCNE1 PPP2R3C PPP2R3C FNDC3A FNDC3A PPP2R2B PPP2R2B PPP2R3A PPP2R3A PPP4R1 PPP4R1 RBL1 RBL1 CDKN2B CDKN2B UBA52 UBA52 FNBP4 FNBP4 CDKN2D CDKN2D E2F3 E2F3 CDKN2C CDKN2C CCND1 CCND1 E2F1 E2F1 CDKN1A CDKN1A PPP2R1B PPP2R1B PPP2CA PPP2CA CCNH CCNH TFDP2 TFDP2 CDK4 CDK4 LOC100733575 LOC100733575 H0WDT2_CAVPO H0WDT2_CAVPO H0WAD6_CAVPO H0WAD6_CAVPO ENSCPOP00000031632 ENSCPOP00000031632 CDK6 CDK6 ENSCPOP00000030705 ENSCPOP00000030705 CDKN1B CDKN1B ENSCPOP00000032613 ENSCPOP00000032613 Ubc Ubc ENSCPOP00000030079 ENSCPOP00000030079 UBB UBB CKS1B CKS1B ENSCPOP00000029251 ENSCPOP00000029251 CKS2 CKS2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H0W9U2_CAVPOUncharacterized protein. (143 aa)
Ccnd2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (288 aa)
H0W160_CAVPOUncharacterized protein. (589 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
CDKN2ACyclin dependent kinase inhibitor 2A. (134 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (211 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (448 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1097 aa)
CDK7Cyclin dependent kinase 7. (335 aa)
JAK2Tyrosine-protein kinase. (1035 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (832 aa)
TFDP1Transcription factor. (411 aa)
Ccne2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (405 aa)
Skp2F-box domain-containing protein. (424 aa)
FNDC3BFibronectin type III domain containing 3B. (1101 aa)
LYNTyrosine-protein kinase. (512 aa)
E2F4E2F transcription factor 4. (411 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
E2F2E2F transcription factor 2. (431 aa)
RB1RB transcriptional corepressor 1. (840 aa)
LOC100734047Uncharacterized protein. (567 aa)
PTK6Tyrosine-protein kinase. (451 aa)
RBL2RB transcriptional corepressor like 2. (1095 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
PPP2CBSerine/threonine-protein phosphatase. (308 aa)
SKP1S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...] (162 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (410 aa)
PPP2R3CProtein phosphatase 2 regulatory subunit B''gamma. (453 aa)
FNDC3AFibronectin type III domain containing 3A. (1172 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (446 aa)
PPP2R3AProtein phosphatase 2 regulatory subunit B''alpha. (1122 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (942 aa)
RBL1RB transcriptional corepressor like 1. (1051 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (131 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
FNBP4Formin binding protein 4. (1044 aa)
CDKN2DCyclin dependent kinase inhibitor 2D. (166 aa)
E2F3E2F transcription factor 3. (457 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (168 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
E2F1E2F transcription factor 1. (389 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (169 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (696 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
TFDP2Transcription factor. (446 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
LOC100733575Uncharacterized protein. (295 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
ENSCPOP00000030705CYCLIN domain-containing protein; Belongs to the cyclin family. (341 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
ENSCPOP00000032613F-box domain-containing protein. (390 aa)
UbcUncharacterized protein. (159 aa)
ENSCPOP00000030079Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (70 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
ENSCPOP00000029251Uncharacterized protein; Belongs to the SKP1 family. (147 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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