(103 nodes) Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S network (Cavia porcellus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPS18	Ribosomal protein S18; Belongs to the universal ribosomal protein uS13 family. (152 aa)
	RPS28	Ribosomal protein S28. (69 aa)
	H0W359_CAVPO	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (159 aa)
	RPS9	Ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (194 aa)
	H0W0Y6_CAVPO	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (238 aa)
	H0W048_CAVPO	Uncharacterized protein; Belongs to the universal ribosomal protein uS19 family. (112 aa)
	LOC100716847	Uncharacterized protein. (80 aa)
	RPS27L	40S ribosomal protein S27. (105 aa)
	EIF4H	Eukaryotic translation initiation factor 4H. (247 aa)
	H0VXS6_CAVPO	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (124 aa)
	H0VW46_CAVPO	Ribosomal_S5_C domain-containing protein. (69 aa)
	H0VVA1_CAVPO	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (211 aa)
	Rps27	40S ribosomal protein S27. (84 aa)
	H0VV17_CAVPO	Uncharacterized protein. (142 aa)
	RPS3A	40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3. (264 aa)
	EIF3H	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (352 aa)
	RPS11	Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family. (158 aa)
	RPS17	Uncharacterized protein. (135 aa)
	LOC100731991	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (115 aa)
	PABPC1L	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (618 aa)
	RPS25	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (125 aa)
	EIF3B	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (791 aa)
	EIF3F	Eukaryotic translation initiation factor 3 subunit F; Belongs to the eIF-3 subunit F family. (325 aa)
	EIF3J	Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (261 aa)
	EIF3I	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (325 aa)
	RPS7	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
	EIF3G	Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (320 aa)
	RPSA	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...] (295 aa)
	EIF4G1	Eukaryotic translation initiation factor 4 gamma 1. (1579 aa)
	RPS4X	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (263 aa)
	EIF3E	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (445 aa)
	EIF4A1	Eukaryotic translation initiation factor 4A1; Belongs to the DEAD box helicase family. (400 aa)
	EIF4E1B	Eukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (246 aa)
	EIF3M	Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (374 aa)
	Rps6	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
	EIF3D	Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...] (582 aa)
	RPS21	40S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family. (86 aa)
	RPS8	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (208 aa)
	Eif2s3	Tr-type G domain-containing protein. (472 aa)
	RPS12	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (132 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
	RPS13	Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (132 aa)
	EIF4EBP2	Eukaryotic translation initiation factor 4E binding protein 2. (121 aa)
	RPS10-NUDT3	S10_plectin domain-containing protein. (165 aa)
	ENSCPOP00000032877	PCI domain-containing protein. (324 aa)
	LOC100730358	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (792 aa)
	EIF4EBP3	Eukaryotic translation initiation factor 4E binding protein 3. (100 aa)
	Rps24	40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family. (140 aa)
	ENSCPOP00000032553	Ribosomal_S10 domain-containing protein. (104 aa)
	EIF3E-2	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (384 aa)
	ENSCPOP00000031834	Uncharacterized protein. (73 aa)
	EIF4EBP1	Eukaryotic translation initiation factor 4E binding protein 1. (118 aa)
	ENSCPOP00000031793	Uncharacterized protein. (352 aa)
	PABPC3	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (586 aa)
	ENSCPOP00000031613	S10_plectin domain-containing protein. (151 aa)
	ENSCPOP00000031523	Uncharacterized protein. (129 aa)
	ENSCPOP00000031008	Ribosomal_S10 domain-containing protein. (116 aa)
	Eif4b	RRM domain-containing protein. (611 aa)
	ENSCPOP00000029461	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (252 aa)
	ENSCPOP00000029431	Uncharacterized protein. (111 aa)
	PABPC4L	Poly(A) binding protein cytoplasmic 4 like. (359 aa)
	RPS19	Ribosomal protein S19. (176 aa)
	ENSCPOP00000029397	Uncharacterized protein. (171 aa)
	Rps2	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (293 aa)
	EIF4A2	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family. (407 aa)
	RPS23	Ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family. (143 aa)
	ENSCPOP00000028770	Q_MOTIF domain-containing protein. (85 aa)
	Rps3	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
	ENSCPOP00000028322	RRM domain-containing protein. (576 aa)
	ENSCPOP00000028144	Q_MOTIF domain-containing protein. (93 aa)
	EIF4E	Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
	ENSCPOP00000027464	Uncharacterized protein. (216 aa)
	ENSCPOP00000026921	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (194 aa)
	EIF2S1	Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
	Rps20	Ribosomal_S10 domain-containing protein. (119 aa)
	Rps16	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family. (146 aa)
	Eif1ax	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (144 aa)
	Rps29	Uncharacterized protein. (56 aa)
	ENSCPOP00000024917	Uncharacterized protein; Belongs to the DEAD box helicase family. (315 aa)
	PABPC4	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
	ENSCPOP00000024505	Helicase C-terminal domain-containing protein. (162 aa)
	Rps15	Uncharacterized protein; Belongs to the universal ribosomal protein uS19 family. (145 aa)
	ENSCPOP00000024068	S1-like domain-containing protein. (129 aa)
	ENSCPOP00000024016	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (237 aa)
	ARL6IP1	ADP ribosylation factor like GTPase 6 interacting protein 1. (203 aa)
	Eif3l	Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (607 aa)
	LOC100729272	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (263 aa)
	EIF3A	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (1363 aa)
	EIF2S2	Eukaryotic translation initiation factor 2 subunit beta. (333 aa)
	LOC100727341	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (913 aa)
	ENSCPOP00000022264	Uncharacterized protein. (566 aa)
	RPS15A	Ribosomal protein S15a; Belongs to the universal ribosomal protein uS8 family. (130 aa)
	EIF3K	Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (218 aa)
	H0WDT2_CAVPO	Ubiquitin-like domain-containing protein. (127 aa)
	Rps26	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (115 aa)
	H0WCY6_CAVPO	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (227 aa)
	RPS5	Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (204 aa)
	H0W7V4_CAVPO	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
	H0W799_CAVPO	Uncharacterized protein. (125 aa)
	H0W774_CAVPO	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (227 aa)
	H0W740_CAVPO	Uncharacterized protein. (126 aa)
	H0W5N6_CAVPO	40S ribosomal protein S27. (84 aa)
	RPS14	Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (151 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL6IP1	EIF2S1	ENSCPOP00000024013	ENSCPOP00000026904	ADP ribosylation factor like GTPase 6 interacting protein 1.	Eukaryotic translation initiation factor 2 subunit alpha.	0.979
ARL6IP1	EIF2S2	ENSCPOP00000024013	ENSCPOP00000022815	ADP ribosylation factor like GTPase 6 interacting protein 1.	Eukaryotic translation initiation factor 2 subunit beta.	0.968
ARL6IP1	EIF3A	ENSCPOP00000024013	ENSCPOP00000023003	ADP ribosylation factor like GTPase 6 interacting protein 1.	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]	0.973
ARL6IP1	EIF3B	ENSCPOP00000024013	ENSCPOP00000011285	ADP ribosylation factor like GTPase 6 interacting protein 1.	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	0.935
ARL6IP1	EIF3D	ENSCPOP00000024013	ENSCPOP00000002302	ADP ribosylation factor like GTPase 6 interacting protein 1.	Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...]	0.973
ARL6IP1	EIF3E	ENSCPOP00000024013	ENSCPOP00000005649	ADP ribosylation factor like GTPase 6 interacting protein 1.	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.939
ARL6IP1	EIF3E-2	ENSCPOP00000024013	ENSCPOP00000032221	ADP ribosylation factor like GTPase 6 interacting protein 1.	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.939
ARL6IP1	EIF3F	ENSCPOP00000024013	ENSCPOP00000011234	ADP ribosylation factor like GTPase 6 interacting protein 1.	Eukaryotic translation initiation factor 3 subunit F; Belongs to the eIF-3 subunit F family.	0.946
ARL6IP1	EIF3G	ENSCPOP00000024013	ENSCPOP00000008407	ADP ribosylation factor like GTPase 6 interacting protein 1.	Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]	0.957
ARL6IP1	EIF3H	ENSCPOP00000024013	ENSCPOP00000013852	ADP ribosylation factor like GTPase 6 interacting protein 1.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.940
ARL6IP1	EIF3I	ENSCPOP00000024013	ENSCPOP00000010790	ADP ribosylation factor like GTPase 6 interacting protein 1.	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.963
ARL6IP1	EIF3J	ENSCPOP00000024013	ENSCPOP00000011153	ADP ribosylation factor like GTPase 6 interacting protein 1.	Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.953
ARL6IP1	EIF3K	ENSCPOP00000024013	ENSCPOP00000021406	ADP ribosylation factor like GTPase 6 interacting protein 1.	Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.966
ARL6IP1	EIF3M	ENSCPOP00000024013	ENSCPOP00000003472	ADP ribosylation factor like GTPase 6 interacting protein 1.	Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.949
ARL6IP1	EIF4A1	ENSCPOP00000024013	ENSCPOP00000004412	ADP ribosylation factor like GTPase 6 interacting protein 1.	Eukaryotic translation initiation factor 4A1; Belongs to the DEAD box helicase family.	0.674
ARL6IP1	EIF4A2	ENSCPOP00000024013	ENSCPOP00000029199	ADP ribosylation factor like GTPase 6 interacting protein 1.	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.	0.581
ARL6IP1	EIF4G1	ENSCPOP00000024013	ENSCPOP00000006613	ADP ribosylation factor like GTPase 6 interacting protein 1.	Eukaryotic translation initiation factor 4 gamma 1.	0.587
ARL6IP1	EIF4H	ENSCPOP00000024013	ENSCPOP00000015635	ADP ribosylation factor like GTPase 6 interacting protein 1.	Eukaryotic translation initiation factor 4H.	0.615
ARL6IP1	ENSCPOP00000022264	ENSCPOP00000024013	ENSCPOP00000022264	ADP ribosylation factor like GTPase 6 interacting protein 1.	Uncharacterized protein.	0.593
ARL6IP1	ENSCPOP00000024016	ENSCPOP00000024013	ENSCPOP00000024016	ADP ribosylation factor like GTPase 6 interacting protein 1.	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.	0.964