60 items (Cavia porcellus) - STRING interaction network

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	TRIM47	Tripartite motif containing 47. (642 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
	POLK	DNA polymerase kappa. (540 aa)
	MEIOB	Meiosis specific with OB-fold. (471 aa)
	RBX1	Ring-box 1. (108 aa)
	CUL4B	Cullin 4B; Belongs to the cullin family. (936 aa)
	RPA3	Replication protein A3. (121 aa)
	DDB1	Damage specific DNA binding protein 1. (1140 aa)
	POLH	DNA polymerase eta. (712 aa)
	RCBTB2	RCC1 and BTB domain containing protein 2. (551 aa)
	RCBTB1	RCC1 and BTB domain containing protein 1. (531 aa)
	NPLOC4	NPL4 homolog, ubiquitin recognition factor. (608 aa)
	Rchy1	Uncharacterized protein. (171 aa)
	UBB	Polyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
	POLI	DNA polymerase iota. (662 aa)
	ENSCPOP00000031632	Ubiquitin-like domain-containing protein. (141 aa)
	Ubc	Uncharacterized protein. (159 aa)
	Pclaf	PAF domain-containing protein. (112 aa)
	VCP	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	UFD1	Ubiquitin recognition factor in ER associated degradation 1. (308 aa)
	RFC1	Replication factor C subunit 1. (1153 aa)
	POLE2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
	SPATA5	Spermatogenesis associated 5. (884 aa)
	USP31	Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family. (1141 aa)
	POLE3	DNA polymerase epsilon 3, accessory subunit. (147 aa)
	Pold4	Uncharacterized protein. (107 aa)
	POLE4	DNA polymerase epsilon 4, accessory subunit. (116 aa)
	POLD1	DNA polymerase. (1134 aa)
	H0WDT2_CAVPO	Ubiquitin-like domain-containing protein. (127 aa)
	LOC100720319	Uncharacterized protein. (644 aa)
	H0WAD6_CAVPO	Ubiquitin-like domain-containing protein. (111 aa)
	REV3L	REV3 like, DNA directed polymerase zeta catalytic subunit. (2940 aa)
	POLD2	DNA polymerase delta 2, accessory subunit. (469 aa)
	MAD2L2	Mitotic arrest deficient 2 like 2. (211 aa)
	ISG15	ISG15 ubiquitin like modifier. (157 aa)
	RFC5	Replication factor C subunit 5. (340 aa)
	USP1	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (764 aa)
	SPRTN	SprT-like N-terminal domain. (481 aa)
	TRIM65	Tripartite motif containing 65. (515 aa)
	DTL	Denticleless E3 ubiquitin protein ligase homolog. (734 aa)
	RAD18	RAD18 E3 ubiquitin protein ligase. (493 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2283 aa)
	TRIM25	Tripartite motif containing 25. (625 aa)
	USP10	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (780 aa)
	RFC2	Replication factor C subunit 2. (352 aa)
	REV1	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1251 aa)
	UBE2L6	Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
	Rps27a	Ubiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
	Pold3	Uncharacterized protein. (466 aa)
	CUL4A	Cullin 4A; Belongs to the cullin family. (759 aa)
	SPATA5L1	Spermatogenesis associated 5 like 1; Belongs to the AAA ATPase family. (634 aa)
	RFC3	Replication factor C subunit 3. (220 aa)
	RPA2	Replication protein A2. (270 aa)
	UBA7	Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1003 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	RFC4	Replication factor C subunit 4. (363 aa)
	ATAD5	ATPase family AAA domain containing 5. (1831 aa)
	WDR48	WD repeat domain 48. (676 aa)
	USP43	Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family. (1016 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	CUL4A	ENSCPOP00000010706	ENSCPOP00000006756	ATPase family AAA domain containing 5.	Cullin 4A; Belongs to the cullin family.	0.613
ATAD5	CUL4B	ENSCPOP00000010706	ENSCPOP00000025466	ATPase family AAA domain containing 5.	Cullin 4B; Belongs to the cullin family.	0.613
ATAD5	DDB1	ENSCPOP00000010706	ENSCPOP00000027409	ATPase family AAA domain containing 5.	Damage specific DNA binding protein 1.	0.642
ATAD5	DTL	ENSCPOP00000010706	ENSCPOP00000013487	ATPase family AAA domain containing 5.	Denticleless E3 ubiquitin protein ligase homolog.	0.869
ATAD5	ENSCPOP00000031632	ENSCPOP00000010706	ENSCPOP00000031632	ATPase family AAA domain containing 5.	Ubiquitin-like domain-containing protein.	0.599
ATAD5	H0WAD6_CAVPO	ENSCPOP00000010706	ENSCPOP00000019948	ATPase family AAA domain containing 5.	Ubiquitin-like domain-containing protein.	0.599
ATAD5	ISG15	ENSCPOP00000010706	ENSCPOP00000016683	ATPase family AAA domain containing 5.	ISG15 ubiquitin like modifier.	0.515
ATAD5	MAD2L2	ENSCPOP00000010706	ENSCPOP00000017570	ATPase family AAA domain containing 5.	Mitotic arrest deficient 2 like 2.	0.681
ATAD5	MEIOB	ENSCPOP00000010706	ENSCPOP00000001396	ATPase family AAA domain containing 5.	Meiosis specific with OB-fold.	0.863
ATAD5	PCNA	ENSCPOP00000010706	ENSCPOP00000008297	ATPase family AAA domain containing 5.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.990
ATAD5	POLD1	ENSCPOP00000010706	ENSCPOP00000021510	ATPase family AAA domain containing 5.	DNA polymerase.	0.862
ATAD5	POLD2	ENSCPOP00000010706	ENSCPOP00000018386	ATPase family AAA domain containing 5.	DNA polymerase delta 2, accessory subunit.	0.728
ATAD5	POLE	ENSCPOP00000010706	ENSCPOP00000012269	ATPase family AAA domain containing 5.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.914
ATAD5	POLE2	ENSCPOP00000010706	ENSCPOP00000003882	ATPase family AAA domain containing 5.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.848
ATAD5	POLE3	ENSCPOP00000010706	ENSCPOP00000022384	ATPase family AAA domain containing 5.	DNA polymerase epsilon 3, accessory subunit.	0.802
ATAD5	POLE4	ENSCPOP00000010706	ENSCPOP00000021626	ATPase family AAA domain containing 5.	DNA polymerase epsilon 4, accessory subunit.	0.744
ATAD5	POLH	ENSCPOP00000010706	ENSCPOP00000027597	ATPase family AAA domain containing 5.	DNA polymerase eta.	0.706
ATAD5	POLI	ENSCPOP00000010706	ENSCPOP00000030490	ATPase family AAA domain containing 5.	DNA polymerase iota.	0.662
ATAD5	POLK	ENSCPOP00000010706	ENSCPOP00000000839	ATPase family AAA domain containing 5.	DNA polymerase kappa.	0.683
ATAD5	Pclaf	ENSCPOP00000010706	ENSCPOP00000032671	ATPase family AAA domain containing 5.	PAF domain-containing protein.	0.599