11 items (Cavia porcellus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	OXCT1	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (520 aa)
	OXCT2	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (503 aa)
	ACAT1	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
	HMGCL	3-hydroxy-3-methylglutaryl-CoA lyase. (325 aa)
	BDH1	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (344 aa)
	Arl9	Uncharacterized protein. (185 aa)
	AACS	Acetoacetyl-CoA synthetase. (672 aa)
	HMGCS2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
	HMGCLL1	3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. (307 aa)
	ACSS3	Acyl-CoA synthetase short chain family member 3. (682 aa)
	BDH2	3-hydroxybutyrate dehydrogenase 2. (245 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AACS	ACAT1	ENSCPOP00000006716	ENSCPOP00000013564	Acetoacetyl-CoA synthetase.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.896
AACS	BDH1	ENSCPOP00000006716	ENSCPOP00000030175	Acetoacetyl-CoA synthetase.	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.817
AACS	BDH2	ENSCPOP00000006716	ENSCPOP00000023284	Acetoacetyl-CoA synthetase.	3-hydroxybutyrate dehydrogenase 2.	0.817
AACS	HMGCL	ENSCPOP00000006716	ENSCPOP00000007766	Acetoacetyl-CoA synthetase.	3-hydroxy-3-methylglutaryl-CoA lyase.	0.815
AACS	HMGCLL1	ENSCPOP00000006716	ENSCPOP00000005600	Acetoacetyl-CoA synthetase.	3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1.	0.817
AACS	HMGCS2	ENSCPOP00000006716	ENSCPOP00000005713	Acetoacetyl-CoA synthetase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.849
AACS	OXCT1	ENSCPOP00000006716	ENSCPOP00000021409	Acetoacetyl-CoA synthetase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.751
AACS	OXCT2	ENSCPOP00000006716	ENSCPOP00000018408	Acetoacetyl-CoA synthetase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.751
ACAT1	AACS	ENSCPOP00000013564	ENSCPOP00000006716	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acetoacetyl-CoA synthetase.	0.896
ACAT1	ACSS3	ENSCPOP00000013564	ENSCPOP00000003117	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA synthetase short chain family member 3.	0.778
ACAT1	BDH1	ENSCPOP00000013564	ENSCPOP00000030175	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.577
ACAT1	BDH2	ENSCPOP00000013564	ENSCPOP00000023284	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxybutyrate dehydrogenase 2.	0.607
ACAT1	HMGCL	ENSCPOP00000013564	ENSCPOP00000007766	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl-CoA lyase.	0.954
ACAT1	HMGCLL1	ENSCPOP00000013564	ENSCPOP00000005600	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1.	0.847
ACAT1	HMGCS2	ENSCPOP00000013564	ENSCPOP00000005713	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.993
ACAT1	OXCT1	ENSCPOP00000013564	ENSCPOP00000021409	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.930
ACAT1	OXCT2	ENSCPOP00000013564	ENSCPOP00000018408	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.930
ACSS3	ACAT1	ENSCPOP00000003117	ENSCPOP00000013564	Acyl-CoA synthetase short chain family member 3.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.778
ACSS3	BDH2	ENSCPOP00000003117	ENSCPOP00000023284	Acyl-CoA synthetase short chain family member 3.	3-hydroxybutyrate dehydrogenase 2.	0.449
ACSS3	HMGCL	ENSCPOP00000003117	ENSCPOP00000007766	Acyl-CoA synthetase short chain family member 3.	3-hydroxy-3-methylglutaryl-CoA lyase.	0.662