72 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FNTA	Farnesyltransferase, CAAX box, alpha. (377 aa)
	DFFB	DNA fragmentation factor subunit beta. (302 aa)
	PTK2	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1084 aa)
	VIM	IF rod domain-containing protein; Belongs to the intermediate filament family. (445 aa)
	APC	APC regulator of WNT signaling pathway. (2842 aa)
	H0UXS2_CAVPO	LTD domain-containing protein. (626 aa)
	BCAP29	B cell receptor associated protein 29. (241 aa)
	STK26	Serine/threonine kinase 26. (410 aa)
	ADD1	Adducin 1. (733 aa)
	HMGB2	High mobility group box 2. (211 aa)
	SH3GLB2	SH3 domain containing GRB2 like, endophilin B2. (398 aa)
	DSG1	Desmoglein 1. (889 aa)
	ENSCPOP00000032936	H15 domain-containing protein. (272 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	SH3GLB1	SH3 domain containing GRB2 like, endophilin B1. (394 aa)
	ENSCPOP00000032088	Uncharacterized protein. (191 aa)
	LMNB1	Lamin B1; Belongs to the intermediate filament family. (496 aa)
	CASP6	Caspase 6; Belongs to the peptidase C14A family. (279 aa)
	CASP8	Caspase 8; Belongs to the peptidase C14A family. (481 aa)
	ENSCPOP00000030204	Uncharacterized protein. (150 aa)
	CAPG	Capping actin protein, gelsolin like. (349 aa)
	ENSCPOP00000030006	H15 domain-containing protein. (273 aa)
	GAS2	Growth arrest specific 2. (314 aa)
	Lmnb2	Uncharacterized protein; Belongs to the intermediate filament family. (617 aa)
	Map2	Microtubule-associated protein. (559 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (705 aa)
	ENSCPOP00000026713	Uncharacterized protein. (267 aa)
	KPNB1	Karyopherin subunit beta 1. (876 aa)
	PRKCD	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
	PKP1	Plakophilin 1. (726 aa)
	LOC100717396	Uncharacterized protein. (1249 aa)
	ACIN1	Apoptotic chromatin condensation inducer 1. (1327 aa)
	HMGB3	High mobility group box 3. (202 aa)
	Hmgb1	annotation not available (215 aa)
	STK24	Serine/threonine kinase 24. (470 aa)
	Tjp2	Uncharacterized protein; Belongs to the MAGUK family. (1176 aa)
	PLEC	Plectin. (4689 aa)
	STK25	Serine/threonine kinase 25. (426 aa)
	LOC101788961	H15 domain-containing protein. (278 aa)
	H1-2	Histone cluster 1 H1 family member c. (213 aa)
	H0WAS6_CAVPO	Uncharacterized protein. (214 aa)
	APC2	APC regulator of WNT signaling pathway 2. (2086 aa)
	LOC100722191	DUF4203 domain-containing protein. (350 aa)
	H0W7U6_CAVPO	H15 domain-containing protein. (269 aa)
	H1-1	Histone cluster 1 H1 family member a. (215 aa)
	LOC100713853	Uncharacterized protein. (547 aa)
	DSG2	Desmoglein 2. (985 aa)
	LOC106027455	H15 domain-containing protein. (211 aa)
	LMNA	Lamin A/C; Belongs to the intermediate filament family. (624 aa)
	CASP10	Caspase 10; Belongs to the peptidase C14A family. (474 aa)
	DNM1L	Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
	BMX	Tyrosine-protein kinase. (655 aa)
	Hp1bp3	Uncharacterized protein. (520 aa)
	Mapt	Microtubule-associated protein. (370 aa)
	Casp3	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (165 aa)
	CDH1	Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (891 aa)
	Clspn	Uncharacterized protein. (1330 aa)
	H1-0	H1 histone family member 0. (194 aa)
	TJP1	Tight junction protein 1; Belongs to the MAGUK family. (1754 aa)
	ROCK1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
	BIRC2	Baculoviral IAP repeat containing 2. (615 aa)
	SPTAN1	Spectrin alpha, non-erythrocytic 1. (2418 aa)
	DFFA	DNA fragmentation factor subunit alpha. (331 aa)
	BCAP31	B cell receptor associated protein 31. (246 aa)
	GSN	Gelsolin. (775 aa)
	KPNA1	Importin subunit alpha; Functions in nuclear protein import. (538 aa)
	DSP	Desmoplakin. (2805 aa)
	HMGB4	High mobility group box 4. (184 aa)
	DBNL	Drebrin like. (437 aa)
	Ocln	Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (521 aa)
	SCIN	Scinderin. (715 aa)
	Casp7	Uncharacterized protein; Belongs to the peptidase C14A family. (199 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACIN1	CASP10	ENSCPOP00000025640	ENSCPOP00000014611	Apoptotic chromatin condensation inducer 1.	Caspase 10; Belongs to the peptidase C14A family.	0.512
ACIN1	CASP6	ENSCPOP00000025640	ENSCPOP00000030989	Apoptotic chromatin condensation inducer 1.	Caspase 6; Belongs to the peptidase C14A family.	0.611
ACIN1	CASP8	ENSCPOP00000025640	ENSCPOP00000030288	Apoptotic chromatin condensation inducer 1.	Caspase 8; Belongs to the peptidase C14A family.	0.512
ACIN1	Casp3	ENSCPOP00000025640	ENSCPOP00000011256	Apoptotic chromatin condensation inducer 1.	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.	0.720
ACIN1	Casp7	ENSCPOP00000025640	ENSCPOP00000004925	Apoptotic chromatin condensation inducer 1.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.634
ACIN1	DFFB	ENSCPOP00000025640	ENSCPOP00000000263	Apoptotic chromatin condensation inducer 1.	DNA fragmentation factor subunit beta.	0.517
ACIN1	ENSCPOP00000030204	ENSCPOP00000025640	ENSCPOP00000030204	Apoptotic chromatin condensation inducer 1.	Uncharacterized protein.	0.499
ACIN1	LOC100722191	ENSCPOP00000025640	ENSCPOP00000019107	Apoptotic chromatin condensation inducer 1.	DUF4203 domain-containing protein.	0.499
APC	APC2	ENSCPOP00000001434	ENSCPOP00000019601	APC regulator of WNT signaling pathway.	APC regulator of WNT signaling pathway 2.	0.860
APC	CDH1	ENSCPOP00000001434	ENSCPOP00000010882	APC regulator of WNT signaling pathway.	Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.	0.544
APC	CTNNB1	ENSCPOP00000001434	ENSCPOP00000032871	APC regulator of WNT signaling pathway.	Catenin beta 1.	0.999
APC	Casp3	ENSCPOP00000001434	ENSCPOP00000011256	APC regulator of WNT signaling pathway.	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.	0.660
APC	ENSCPOP00000030204	ENSCPOP00000001434	ENSCPOP00000030204	APC regulator of WNT signaling pathway.	Uncharacterized protein.	0.446
APC	LOC100722191	ENSCPOP00000001434	ENSCPOP00000019107	APC regulator of WNT signaling pathway.	DUF4203 domain-containing protein.	0.449
APC	ROCK1	ENSCPOP00000001434	ENSCPOP00000009405	APC regulator of WNT signaling pathway.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.417
APC2	APC	ENSCPOP00000019601	ENSCPOP00000001434	APC regulator of WNT signaling pathway 2.	APC regulator of WNT signaling pathway.	0.860
APC2	CDH1	ENSCPOP00000019601	ENSCPOP00000010882	APC regulator of WNT signaling pathway 2.	Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.	0.401
APC2	CTNNB1	ENSCPOP00000019601	ENSCPOP00000032871	APC regulator of WNT signaling pathway 2.	Catenin beta 1.	0.990
APC2	Casp3	ENSCPOP00000019601	ENSCPOP00000011256	APC regulator of WNT signaling pathway 2.	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.	0.642
APC2	ENSCPOP00000030204	ENSCPOP00000019601	ENSCPOP00000030204	APC regulator of WNT signaling pathway 2.	Uncharacterized protein.	0.446