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| | EPS15 | Epidermal growth factor receptor pathway substrate 15. (935 aa) |
| | CLTA | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (242 aa) |
| | EPS15L1 | Epidermal growth factor receptor pathway substrate 15 like 1. (905 aa) |
| | UBL7 | Ubiquitin like 7. (380 aa) |
| | ENSCPOP00000024297 | Uncharacterized protein. (406 aa) |
| | Tgoln2 | Uncharacterized protein. (323 aa) |
| | LOC100721922 | Uncharacterized protein; Belongs to the transferrin family. (700 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | PICALM | Phosphatidylinositol binding clathrin assembly protein. (660 aa) |
| | AP2M1 | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (435 aa) |
| | COPS8 | COP9 signalosome subunit 8. (209 aa) |
| | SYT8 | Synaptotagmin 8. (398 aa) |
| | LDLR | Low density lipoprotein receptor. (807 aa) |
| | LOC100717727 | Uncharacterized protein. (510 aa) |
| | H0WDT2_CAVPO | Ubiquitin-like domain-containing protein. (127 aa) |
| | BTC | Betacellulin. (183 aa) |
| | TOR1B | Torsin. (338 aa) |
| | H0WAD6_CAVPO | Ubiquitin-like domain-containing protein. (111 aa) |
| | SH3GL1 | SH3 domain containing GRB2 like 1, endophilin A2. (359 aa) |
| | HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (778 aa) |
| | AP2S1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (148 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (737 aa) |
| | CD3G | CD3g molecule. (181 aa) |
| | ADRB2 | Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. (418 aa) |
| | COPS4 | COP9 signalosome subunit 4. (371 aa) |
| | H0W3X9_CAVPO | Uncharacterized protein. (2048 aa) |
| | VAMP7 | Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (210 aa) |
| | EPN3 | Epsin 3. (635 aa) |
| | VAMP5 | Vesicle associated membrane protein 5. (100 aa) |
| | SLC18A3 | Solute carrier family 18 member A3. (533 aa) |
| | COPS6 | COP9 signalosome subunit 6. (325 aa) |
| | AVP | Vasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin; Belongs to the vasopressin/oxytocin family. (159 aa) |
| | SH3GL2 | SH3 domain containing GRB2 like 2, endophilin A1. (376 aa) |
| | Kiaa0319 | Uncharacterized protein. (483 aa) |
| | CHRM2 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa) |
| | VAMP4 | Vesicle associated membrane protein 4. (163 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (538 aa) |
| | ENTHD1 | ENTH domain containing 1. (601 aa) |
| | ZFYVE19 | Zinc finger FYVE-type containing 19. (390 aa) |
| | ZFYVE1 | Zinc finger FYVE-type containing 1. (777 aa) |
| | EPGN | Epithelial mitogen. (133 aa) |
| | ITSN2 | Intersectin 2. (1684 aa) |
| | UBQLN2 | Ubiquilin 2. (624 aa) |
| | IGF2R | Insulin like growth factor 2 receptor. (2473 aa) |
| | CD3D | CD3d molecule. (171 aa) |
| | SCARB2 | Scavenger receptor class B member 2; Belongs to the CD36 family. (439 aa) |
| | CFTR | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1448 aa) |
| | AVPR2 | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (368 aa) |
| | SLC2A8 | Solute carrier family 2 member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (477 aa) |
| | Cd4 | Uncharacterized protein. (523 aa) |
| | SGIP1 | SH3 domain GRB2 like endophilin interacting protein 1. (825 aa) |
| | NETO2 | Neuropilin and tolloid like 2. (520 aa) |
| | COPS5 | COP9 signalosome subunit 5. (334 aa) |
| | BMP2K | BMP2 inducible kinase. (1072 aa) |
| | AP2A2 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (937 aa) |
| | NEDD8 | NEDD8 ubiquitin like modifier. (83 aa) |
| | FCHO1 | FCH domain only 1. (892 aa) |
| | HBEGF | Heparin binding EGF like growth factor. (208 aa) |
| | Ap2b1 | AP complex subunit beta. (951 aa) |
| | SYT4 | Synaptotagmin 4. (425 aa) |
| | GRK3 | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (673 aa) |
| | TGFA | Transforming growth factor alpha. (159 aa) |
| | NETO1 | Neuropilin and tolloid like 1. (450 aa) |
| | TOR1A | Torsin. (332 aa) |
| | STAM | Signal transducing adaptor molecule. (537 aa) |
| | GPR52 | G protein-coupled receptor 52; Belongs to the G-protein coupled receptor 1 family. (263 aa) |
| | Epn1 | ENTH domain-containing protein. (54 aa) |
| | Dab2 | PID domain-containing protein. (766 aa) |
| | KIAA0319L | KIAA0319 like. (1069 aa) |
| | H0VBH1_CAVPO | Uncharacterized protein. (134 aa) |
| | UBQLN3 | Ubiquilin 3. (638 aa) |
| | AGTR1 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system (By similarity); Belongs to the G-protein coupled receptor 1 family. (359 aa) |
| | M6PR | Mannose-6-phosphate receptor, cation dependent. (278 aa) |
| | SH3KBP1 | SH3 domain containing kinase binding protein 1. (716 aa) |
| | AGFG2 | ArfGAP with FG repeats 2. (478 aa) |
| | Rps27a | Ubiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa) |
| | MCTP2 | Multiple C2 and transmembrane domain containing 2. (865 aa) |
| | COPS3 | COP9 signalosome subunit 3. (423 aa) |
| | CLTC | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa) |
| | AP2A1 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (978 aa) |
| | Vamp2 | V-SNARE coiled-coil homology domain-containing protein. (164 aa) |
| | ENSCPOP00000030527 | Uncharacterized protein. (111 aa) |
| | EREG | Epiregulin. (164 aa) |
| | UBB | Polyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa) |
| | MCTP1 | Multiple C2 and transmembrane domain containing 1. (763 aa) |
| | APOB | Apolipoprotein B. (4479 aa) |
| | SYT11 | Synaptotagmin 11. (431 aa) |
| | UBQLN1 | Ubiquilin 1. (589 aa) |
| | EPN2 | Epsin 2. (646 aa) |
| | AAK1 | AP2 associated kinase 1. (957 aa) |
| | SYT9 | Synaptotagmin 9. (487 aa) |
| | SH3GL3 | SH3 domain containing GRB2 like 3, endophilin A3. (346 aa) |
| | NECAP2 | NECAP endocytosis associated 2. (266 aa) |
| | COPS2 | COP9 signalosome subunit 2. (443 aa) |
| | SYT2 | Synaptotagmin 2. (421 aa) |
| | REPS2 | RALBP1 associated Eps domain containing 2. (561 aa) |
| | STAM2 | Signal transducing adaptor molecule 2. (519 aa) |
| | UBQLN4 | Ubiquilin 4. (593 aa) |
| | SYT1 | Synaptotagmin 1. (422 aa) |
| | GPS1 | G protein pathway suppressor 1. (487 aa) |
| | SNAP91 | Synaptosome associated protein 91. (896 aa) |
| | VAMP8 | Vesicle associated membrane protein 8. (101 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1194 aa) |
| | REPS1 | RALBP1 associated Eps domain containing 1. (787 aa) |
| | ITSN1 | Intersectin 1. (1657 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | COPS7A | COP9 signalosome subunit 7A. (275 aa) |
| | NECAP1 | NECAP endocytosis associated 1. (274 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1214 aa) |
| | ARRB1 | Arrestin beta 1. (430 aa) |
| | CBL | Cbl proto-oncogene. (894 aa) |
| | STON2 | Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family. (894 aa) |
| | FCHO2 | FCH domain only 2. (830 aa) |
| | IL7R | Interleukin 7 receptor. (461 aa) |
| | CLTB | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa) |
| | TFRC | Transferrin receptor protein 1. (765 aa) |
| | ENSCPOP00000026864 | V-SNARE coiled-coil homology domain-containing protein. (102 aa) |
| | CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin. (705 aa) |
| | VAMP3 | Vesicle associated membrane protein 3. (100 aa) |
| | AREG | Amphiregulin. (241 aa) |
| | CLTCL1 | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1676 aa) |
| | ENSCPOP00000033061 | AP complex subunit beta. (889 aa) |
| | Ston1 | Stonin-1; May be involved in the endocytic machinery. (734 aa) |
| | ARRB2 | Arrestin beta 2. (417 aa) |
| | GRK2 | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (750 aa) |
| | LOC100725073 | PID domain-containing protein. (745 aa) |
| | LMBRD2 | LMBR1 domain containing 2. (685 aa) |
| | Ubc | Uncharacterized protein. (159 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | ENSCPOP00000031632 | Ubiquitin-like domain-containing protein. (141 aa) |
| | COPS7B | COP9 signalosome subunit 7B. (264 aa) |
| | LDLRAP1 | Low density lipoprotein receptor adaptor protein 1. (308 aa) |
| | TACR1 | Substance-P receptor; This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. (407 aa) |
