STRINGSTRING
PSMD13 PSMD13 PSME3 PSME3 Psma2 Psma2 Ubc Ubc PSME2 PSME2 Spib Spib ENSCPOP00000031632 ENSCPOP00000031632 PSMC1 PSMC1 UBB UBB PSMA6 PSMA6 PSMB2 PSMB2 LMO2 LMO2 TCF3 TCF3 PSMD12 PSMD12 TP73 TP73 PSMD4 PSMD4 PSMD14 PSMD14 LMO3 LMO3 PSMD2 PSMD2 PSMC3 PSMC3 CCNH CCNH PSME1 PSME1 ENSCPOP00000023065 ENSCPOP00000023065 PSMA3 PSMA3 LDB2 LDB2 PSMD1 PSMD1 H0WDT2_CAVPO H0WDT2_CAVPO PSMB10 PSMB10 H0WAD6_CAVPO H0WAD6_CAVPO PSMD5 PSMD5 PSMB11 PSMB11 PSMB3 PSMB3 LMO1 LMO1 PSMA4 PSMA4 Psmd9 Psmd9 H0VWS1_CAVPO H0VWS1_CAVPO SPI1 SPI1 PSMC2 PSMC2 PSMA1 PSMA1 PSMB4 PSMB4 PSMD3 PSMD3 Psmd10 Psmd10 CDK7 CDK7 MYB MYB MNAT1 MNAT1 PSMA7 PSMA7 PSMB5 PSMB5 ITCH ITCH PSMF1 PSMF1 PSMA5 PSMA5 PSMA8 PSMA8 PSME4 PSME4 PSMC5 PSMC5 PSMD7 PSMD7 PSMD8 PSMD8 H0VHS7_CAVPO H0VHS7_CAVPO LDB1 LDB1 GATA2 GATA2 PSMD11 PSMD11 PSMC6 PSMC6 GATA3 GATA3 PSMB7 PSMB7 GATA1 GATA1 PSMD6 PSMD6 Rps27a Rps27a Kmt2a Kmt2a PSMC4 PSMC4 TAL1 TAL1 PSMB9 PSMB9 PSMB6 PSMB6 PSMB1 PSMB1 PSMB8 PSMB8 UBA52 UBA52
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD13Proteasome 26S subunit, non-ATPase 13. (315 aa)
PSME3Proteasome activator subunit 3. (254 aa)
Psma2Proteasome subunit alpha type. (234 aa)
UbcUncharacterized protein. (159 aa)
PSME2Proteasome activator subunit 2. (239 aa)
SpibETS domain-containing protein. (263 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMB2Proteasome subunit beta. (201 aa)
LMO2LIM domain only 2. (232 aa)
TCF3Transcription factor 3. (648 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (641 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (377 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
LMO3LIM domain only 3. (147 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
PSME1Proteasome activator subunit 1. (249 aa)
ENSCPOP00000023065ANK_REP_REGION domain-containing protein. (179 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
LDB2LIM domain binding 2. (390 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
PSMB10Proteasome subunit beta. (273 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PSMB11Proteasome subunit beta. (297 aa)
PSMB3Proteasome subunit beta. (207 aa)
LMO1LIM domain only 1. (158 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
Psmd9PDZ domain-containing protein. (223 aa)
H0VWS1_CAVPOANK_REP_REGION domain-containing protein. (213 aa)
SPI1Spi-1 proto-oncogene. (258 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (458 aa)
PSMA1Proteasome subunit alpha type. (270 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (263 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
Psmd10ANK_REP_REGION domain-containing protein. (232 aa)
CDK7Cyclin dependent kinase 7. (335 aa)
MYBMYB proto-oncogene, transcription factor. (743 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
PSMA7Proteasome endopeptidase complex. (248 aa)
PSMB5Proteasome subunit beta. (263 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PSME4Proteasome activator subunit 4. (1827 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
H0VHS7_CAVPOUncharacterized protein. (85 aa)
LDB1LIM domain binding 1. (401 aa)
GATA2GATA binding protein 2. (374 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
GATA3GATA binding protein 3. (443 aa)
PSMB7Proteasome subunit beta. (277 aa)
GATA1GATA binding protein 1. (401 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
Kmt2aHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (2938 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (191 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMB8Proteasome subunit beta. (273 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.