15 items (Cavia porcellus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Your Input:
	APOA1	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (264 aa)
	SMPDL3A	Sphingomyelin phosphodiesterase acid like 3A. (410 aa)
	LOC100728240	Uncharacterized protein. (1366 aa)
	ABCA1	ATP binding cassette subfamily A member 1. (2200 aa)
	ZDHHC19	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (320 aa)
	ZDHHC8	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (751 aa)
	A2M	Alpha-2-macroglobulin. (1475 aa)
	PTCHD4	Patched domain containing 4. (895 aa)
	Mug1	Uncharacterized protein. (1377 aa)
	PTCHD3	Patched domain containing 3. (813 aa)
	PLEKHD1	Pleckstrin homology and coiled-coil domain containing D1. (506 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	PTCHD1	Patched domain containing 1. (888 aa)
	BMP1	Metalloendopeptidase. (986 aa)
	Prkaca	Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A2M	APOA1	ENSCPOP00000000065	ENSCPOP00000032306	Alpha-2-macroglobulin.	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	0.648
ABCA1	APOA1	ENSCPOP00000008428	ENSCPOP00000032306	ATP binding cassette subfamily A member 1.	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	0.962
ABCA1	PRKACB	ENSCPOP00000008428	ENSCPOP00000026584	ATP binding cassette subfamily A member 1.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.584
ABCA1	Prkaca	ENSCPOP00000008428	ENSCPOP00000032930	ATP binding cassette subfamily A member 1.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.582
APOA1	A2M	ENSCPOP00000032306	ENSCPOP00000000065	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	Alpha-2-macroglobulin.	0.648
APOA1	ABCA1	ENSCPOP00000032306	ENSCPOP00000008428	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	ATP binding cassette subfamily A member 1.	0.962
APOA1	BMP1	ENSCPOP00000032306	ENSCPOP00000014968	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	Metalloendopeptidase.	0.532
APOA1	LOC100728240	ENSCPOP00000032306	ENSCPOP00000009756	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	Uncharacterized protein.	0.625
APOA1	Mug1	ENSCPOP00000032306	ENSCPOP00000019371	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	Uncharacterized protein.	0.648
BMP1	APOA1	ENSCPOP00000014968	ENSCPOP00000032306	Metalloendopeptidase.	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	0.532
LOC100728240	APOA1	ENSCPOP00000009756	ENSCPOP00000032306	Uncharacterized protein.	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	0.625
Mug1	APOA1	ENSCPOP00000019371	ENSCPOP00000032306	Uncharacterized protein.	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.	0.648
PRKACB	ABCA1	ENSCPOP00000026584	ENSCPOP00000008428	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	ATP binding cassette subfamily A member 1.	0.584
PRKACB	Prkaca	ENSCPOP00000026584	ENSCPOP00000032930	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.916
Prkaca	ABCA1	ENSCPOP00000032930	ENSCPOP00000008428	Uncharacterized protein; Belongs to the protein kinase superfamily.	ATP binding cassette subfamily A member 1.	0.582
Prkaca	PRKACB	ENSCPOP00000032930	ENSCPOP00000026584	Uncharacterized protein; Belongs to the protein kinase superfamily.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.916