STRINGSTRING
LOC100731150 LOC100731150 KANK4 KANK4 GTF2A1L GTF2A1L HIST3H3 HIST3H3 POLR2G POLR2G TBP TBP LOC106027456 LOC106027456 POLR2K POLR2K KDM1A KDM1A ENSCPOP00000030090 ENSCPOP00000030090 GTF2F2 GTF2F2 POLR2F POLR2F GTF2A2 GTF2A2 PTGES3 PTGES3 ENSCPOP00000029297 ENSCPOP00000029297 C11orf88 C11orf88 POLR2H POLR2H ENSCPOP00000026646 ENSCPOP00000026646 ENSCPOP00000026400 ENSCPOP00000026400 LOC100713990 LOC100713990 NRIP1 NRIP1 EBAG9 EBAG9 POLR2B POLR2B POLR2L POLR2L LOC100728325 LOC100728325 H2BC18 H2BC18 CXXC5 CXXC5 ENSCPOP00000024615 ENSCPOP00000024615 ENSCPOP00000024383 ENSCPOP00000024383 HIST2H2BE HIST2H2BE ENSCPOP00000024347 ENSCPOP00000024347 ENSCPOP00000024311 ENSCPOP00000024311 LOC100733876 LOC100733876 ENSCPOP00000024251 ENSCPOP00000024251 ENSCPOP00000024231 ENSCPOP00000024231 H3-3A H3-3A Pgr Pgr ENSCPOP00000023894 ENSCPOP00000023894 NCOA1 NCOA1 CARM1 CARM1 KANK1 KANK1 LOC100717510 LOC100717510 LOC100725824 LOC100725824 KAT5 KAT5 ZC3H12C ZC3H12C LOC100735825 LOC100735825 LOC100735546 LOC100735546 PRMT1 PRMT1 H3F3B H3F3B LOC100735042 LOC100735042 LOC111756490 LOC111756490 TLE3 TLE3 SP1 SP1 GREB1L GREB1L LOC100730459 LOC100730459 LOC100732911 LOC100732911 ENSCPOP00000029061 ENSCPOP00000029061 ZC3H12A ZC3H12A H0VHS7_CAVPO H0VHS7_CAVPO Cdk9 Cdk9 H0VDT0_CAVPO H0VDT0_CAVPO GATA3 GATA3 ESR1 ESR1 TRPS1 TRPS1 NCOA3 NCOA3 DDX5 DDX5 GREB1 GREB1 PRMT8 PRMT8 EP300 EP300 POLR2C POLR2C LOC100728920 LOC100728920 ZNF217 ZNF217 KANK2 KANK2 JUND JUND FOSB FOSB POLR2A POLR2A ZC3H12D ZC3H12D MYB MYB MOV10 MOV10 H2BC1 H2BC1 GTF2F1 GTF2F1 USF2 USF2 POLR2I POLR2I USF1 USF1 HSP90AB1 HSP90AB1 Cited1 Cited1 GTF2A1 GTF2A1 CHD1 CHD1 POLR2D POLR2D FKBP4 FKBP4 Hsp90aa1 Hsp90aa1 POLR2E POLR2E Polr2j Polr2j CCNT1 CCNT1 TBPL1 TBPL1 ENSCPOP00000028672 ENSCPOP00000028672 ERBB4 ERBB4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100731150annotation not available (103 aa)
KANK4KN motif and ankyrin repeat domains 4. (859 aa)
GTF2A1LGeneral transcription factor IIA subunit 1 like. (468 aa)
HIST3H3Histone cluster 3 H3. (128 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
TBPTATA-box binding protein. (321 aa)
LOC106027456annotation not available (126 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (865 aa)
ENSCPOP00000030090annotation not available (126 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
PTGES3Prostaglandin E synthase 3. (160 aa)
ENSCPOP00000029297annotation not available (103 aa)
C11orf88Chromosome 11 open reading frame 88. (168 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
ENSCPOP00000026646annotation not available (126 aa)
ENSCPOP00000026400annotation not available (125 aa)
LOC100713990Histone H2B; Belongs to the histone H2B family. (126 aa)
NRIP1Nuclear receptor interacting protein 1. (1157 aa)
EBAG9Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. (213 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
LOC100728325annotation not available (103 aa)
H2BC18Histone H2B; Belongs to the histone H2B family. (126 aa)
CXXC5CXXC finger protein 5. (317 aa)
ENSCPOP00000024615Bromo domain-containing protein. (84 aa)
ENSCPOP00000024383annotation not available (126 aa)
HIST2H2BEHistone H2B; Belongs to the histone H2B family. (126 aa)
ENSCPOP00000024347annotation not available (103 aa)
ENSCPOP00000024311annotation not available (126 aa)
LOC100733876annotation not available (103 aa)
ENSCPOP00000024251ANK_REP_REGION domain-containing protein. (179 aa)
ENSCPOP00000024231annotation not available (136 aa)
H3-3AH3.3 histone A. (136 aa)
PgrUncharacterized protein. (428 aa)
ENSCPOP00000023894annotation not available (126 aa)
NCOA1Nuclear receptor coactivator. (1442 aa)
CARM1Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (641 aa)
KANK1KN motif and ankyrin repeat domains 1. (1353 aa)
LOC100717510Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100725824HATPase_c domain-containing protein. (695 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (541 aa)
ZC3H12CZinc finger CCCH-type containing 12C. (886 aa)
LOC100735825Histone H3; Belongs to the histone H3 family. (136 aa)
LOC100735546Histone H2B; Belongs to the histone H2B family. (126 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
H3F3BHistone H3; Belongs to the histone H3 family. (136 aa)
LOC100735042Histone domain-containing protein; Belongs to the histone H2B family. (125 aa)
LOC111756490Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
TLE3TLE family member 3, transcriptional corepressor. (769 aa)
SP1Sp1 transcription factor. (786 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1884 aa)
LOC100730459Uncharacterized protein. (280 aa)
LOC100732911P-type domain-containing protein. (56 aa)
ENSCPOP00000029061annotation not available (126 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (550 aa)
H0VHS7_CAVPOUncharacterized protein. (85 aa)
Cdk9Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (372 aa)
H0VDT0_CAVPOProtein kinase domain-containing protein. (337 aa)
GATA3GATA binding protein 3. (443 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (596 aa)
TRPS1Transcriptional repressor GATA binding 1. (1285 aa)
NCOA3Nuclear receptor coactivator. (1418 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
GREB1Uncharacterized protein. (1882 aa)
PRMT8Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (376 aa)
EP300E1A binding protein p300. (2425 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
LOC100728920Histone domain-containing protein; Belongs to the histone H2B family. (128 aa)
ZNF217Zinc finger protein 217. (914 aa)
KANK2KN motif and ankyrin repeat domains 2. (841 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (320 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (340 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1833 aa)
ZC3H12DZinc finger CCCH-type containing 12D. (464 aa)
MYBMYB proto-oncogene, transcription factor. (743 aa)
MOV10Mov10 RISC complex RNA helicase. (1063 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (522 aa)
USF2Upstream transcription factor 2, c-fos interacting. (360 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
USF1Upstream transcription factor 1. (310 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (723 aa)
Cited1Uncharacterized protein. (61 aa)
GTF2A1General transcription factor IIA subunit 1. (377 aa)
CHD1Chromodomain helicase DNA binding protein 1. (1666 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
FKBP4Peptidylprolyl isomerase. (458 aa)
Hsp90aa1Heat shock protein 90 alpha family class A member 1. (733 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
Polr2jRNA polymerase II subunit J. (117 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (727 aa)
TBPL1TATA-box binding protein like 1. (179 aa)
ENSCPOP00000028672annotation not available (136 aa)
ERBB4Receptor protein-tyrosine kinase. (1263 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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